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New NIH-funded project aims to turn rare HIV cures into broadly applicable immunotherapy

Nearly 20 years ago, a man named Timothy Ray Brown who was living with HIV and cancer, underwent two courses of stem cell transplantation to treat his acute myeloid leukemia.

28 Aug 2025

Routine eye exams may help detect Alzheimer’s years before symptoms appear

Within the next few years, doctors may be able to spot signs of Alzheimer's disease and other dementias using routine eye exams well before symptoms appear, a new study suggests.

27 Aug 2025

Regenerative strategy offers hope for women with pelvic organ prolapse

Pelvic organ prolapse (POP) is a disorder that primarily affects older women who have experienced multiple vaginal childbirths.

27 Aug 2025

New research reveals why blood clotting malfunctions in inflammatory bowel disease

Inflammatory bowel disease, in which the immune system attacks the gut, is a painful chronic condition that affects three million Americans. Rates of IBD are rising, and there's currently no cure. IBD can also be deadly: up to 8% of people with the disease develop blood clots, which can lead to heart attack and stroke.

25 Aug 2025

ATOX1 drives hepatocellular carcinoma progression through c-Myb and PI3K/AKT activation

Despite advancements in diagnostic and therapeutic strategies, hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality.

22 Aug 2025

New formulation of chemotherapy drug opens doors to advanced cancer treatment options

University of Arizona researchers devised a new method to deliver cancer chemotherapy drugs to pancreatic and breast cancer tumors more effectively and with less damage to healthy tissues than standard forms of chemotherapy.

21 Aug 2025

Hyperactivity in reticular thalamic nucleus drives autism-like behaviors in mice

Stanford Medicine scientists investigating the neurological underpinnings of autism spectrum disorder have found that hyperactivity in a specific brain region could drive behaviors commonly associated with the disorder.

20 Aug 2025

Ciliary Hedgehog signaling controls the fate of fat precursor cells

Too much fat can be unhealthy: how fat cells, so-called adipocytes, develop, is crucial for the function of the fat tissue.

20 Aug 2025

Somatic mutations drive vascular aging and muscle weakness over time

Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over time can affect aging.

20 Aug 2025

SNAP25 identified as key to sour taste perception and cell survival

The tongue contains numerous taste buds-tiny sensory organs responsible for detecting taste. Taste buds consist of specialized cells that translate chemical stimuli into neural signals.

19 Aug 2025

Impaired blood flow alters immunity and fuels tumor progression

Cutting off blood flow can prematurely age the bone marrow, weakening the immune system's ability to fight cancer, according to a new study from NYU Langone Health.

19 Aug 2025

Researchers investigate how citrus bioflavonoid naringin could reduce inflammation and heart risk

Researchers reviewed 62 studies on naringin, a citrus flavonoid, and found strong preclinical evidence for its cardioprotective effects, including improved endothelial function, reduced oxidative stress, and protection against myocardial injury.

18 Aug 2025

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain tissues.

18 Aug 2025

Respiratory viruses awaken dormant breast cancer cells and raise relapse risk

Respiratory viruses such as influenza and COVID-19 can reactivate dormant breast cancer cells in the lungs, raising the risk of metastasis. The process is driven by IL-6–induced cell changes and immune suppression, with the highest recurrence risk soon after infection.

14 Aug 2025

Artificial intelligence enables discovery of novel compounds to fight drug-resistant bacteria

With help from artificial intelligence, MIT researchers have designed novel antibiotics that can combat two hard-to-treat infections: drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA).

14 Aug 2025

Gene editing restores hearing and balance in adult mice with DFNA41 deafness

Zheng-Yi Chen, DPhil, associate scientist at the Eaton-Peabody Laboratories, and Ines and Fredrick Yeatts Chair in Otolaryngology, at Mass Eye and Ear, is the senior and co-corresponding author of a paper published in the Journal of Clinical Investigation, "Single Dose Genome Editing Therapy Rescues Auditory and Vestibular Functions in Adult Mice with DFNA41 Deafness."

14 Aug 2025

Microbes found to play a key role in shaping early brain development

New research from Michigan State University finds that microbes play an important role in shaping early brain development, specifically in a key brain region that controls stress, social behavior, and vital body functions.

13 Aug 2025

New mouse model reveals key role of osteocytes in osteogenesis imperfecta

Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to be abnormal, leading to an increased risk of fractures.

13 Aug 2025

Old Parkinson's medication offers new hope for tuberculosis treatment

A medication developed in the 1950s to treat Parkinson's disease may offer a powerful new tool in the fight against tuberculosis (TB), according to new research from the University of British Columbia.

12 Aug 2025

Natural gut molecule reverses liver damage and repairs gut lining

UC Davis Health researchers have discovered that a natural molecule made by gut bacteria can reverse liver damage and repair the gut lining after aflatoxin exposure.

12 Aug 2025

Mouse Model News and Research

New NIH-funded project aims to turn rare HIV cures into broadly applicable immunotherapy

Routine eye exams may help detect Alzheimer’s years before symptoms appear

Regenerative strategy offers hope for women with pelvic organ prolapse

New research reveals why blood clotting malfunctions in inflammatory bowel disease

ATOX1 drives hepatocellular carcinoma progression through c-Myb and PI3K/AKT activation

New formulation of chemotherapy drug opens doors to advanced cancer treatment options

Hyperactivity in reticular thalamic nucleus drives autism-like behaviors in mice

Ciliary Hedgehog signaling controls the fate of fat precursor cells

Somatic mutations drive vascular aging and muscle weakness over time

SNAP25 identified as key to sour taste perception and cell survival

Impaired blood flow alters immunity and fuels tumor progression

Researchers investigate how citrus bioflavonoid naringin could reduce inflammation and heart risk

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

Respiratory viruses awaken dormant breast cancer cells and raise relapse risk

Artificial intelligence enables discovery of novel compounds to fight drug-resistant bacteria

Gene editing restores hearing and balance in adult mice with DFNA41 deafness

Microbes found to play a key role in shaping early brain development

New mouse model reveals key role of osteocytes in osteogenesis imperfecta

Old Parkinson's medication offers new hope for tuberculosis treatment

Natural gut molecule reverses liver damage and repairs gut lining

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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