Tetanus News and Research

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Tetanus is a severe, frequently fatal disease caused by an exotoxin produced by Clostridium tetani, a bacterium that is found in the environment. Tetanus is not transmitted from person to person. Rather, Clostridium tetani enters the body through an open wound, including lacerations, abrasions and puncture wounds. The toxin causes neuromuscular dysfunction, with rigidity and spasms of skeletal muscles. The muscle spasms usually start in the jaw (which is why the disease is sometimes called "lockjaw") and neck and may spread to many other muscles, leading to generalized paralysis.

Merck announces FDA approval for GARDASIL against HPV-related anal cancer

Merck, known as MSD outside the United States and Canada, announced today that the U.S. Food and Drug Administration (FDA) has approved GARDASIL® [Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant] for the prevention of anal cancer caused by human papillomavirus (HPV) types 16 and 18 and for the prevention of anal intraepithelial neoplasia (AIN) grades 1, 2 and 3 (anal dysplasias and precancerous lesions) caused by HPV types 6, 11, 16 and 18, in males and females 9 through 26 years of age.

23 Dec 2010

Sanofi Pasteur commences phase II clinical study of vaccine for Clostridium difficile infection prevention

Sanofi Pasteur, the vaccines division of sanofi-aventis Group, announced today that it has started its phase II clinical study of a vaccine for primary prevention of Clostridium difficile infection (CDI). The trial starting in the United States is focused on evaluating prevention of the first episode of CDI in at-risk individuals, which includes adults with imminent hospitalization or current or impending residence in a long-term care or rehabilitation facility.

30 Nov 2010

GAVI says pentavalent vaccine price to fall, but $3.7B still needed to vaccinate children in developing countries

The average price of a vaccine that protects children against five diseases is expected to "drop to $2.58 next year compared to the current average price of $2.97," the GAVI Alliance said Friday, Reuters reports. The group credits the expected price decline, which "represents a decrease of 30 percent over the last seven years," in part to an "increased demand for the pentavalent, or five-in-one vaccine," according to the news service (Kelland, 11/26).

30 Nov 2010

Merck announces FDA Advisory Committee approval of GARDASIL for anal cancer and AIN treatment

Merck announced today that the U.S. Food and Drug Administration's (FDA) Vaccines and Related Biological Products Advisory Committee has advised that the data presented support an indication for GARDASIL® [Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant] for the prevention of anal cancer and anal intraepithelial neoplasia (AIN) in both males and females 9 through 26 years of age.

18 Nov 2010

Researchers develop new vaccine delivery system for rotavirus infection

Researchers have developed a promising new approach to vaccination for rotavirus, a common cause of severe diarrheal disease that is responsible for approximately 500,000 deaths among children in the developing world every year.

16 Nov 2010

Vaccinations do not increase risk of RA

Common adult vaccinations are not associated with an increased risk of developing rheumatoid arthritis, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Atlanta.

9 Nov 2010

Recent releases in Global Health

Global Fund Will Make 'Every Possible Effort' To Raise Additional Resources: Although pledges to the Global Fund to Fight AIDS, Tuberculosis and Malaria at its recent replenishment meeting did not meet "the lowest estimate of demand," the Fund "will make every possible effort to raise the additional resources that we expect countries to request in the years ahead" through new donor recruitment and "innovative financing approaches," writes Executive Director Michael Kazatchkine in a Lancet comment

30 Oct 2010

University of Padua Professor wins Paul Ehrlich and Ludwig Darmstaedter Prize

Frankfurt am Main. The chemist and biologist Professor Cesare Montecucco, 62, of the Department of Biomedical Research at the University of Padua, Italy, has won the 100,000 euro Paul Ehrlich and Ludwig Darmstaedter Prize 2011 for his contribution to research in the field of bacterial diseases, including tetanus, botulism, anthrax and Helicobacter pylori associated diseases.

27 Oct 2010

Today's Op-Eds: Critiques of 'Obamacare,' Skyrocketing brand name drug prices, pay-for-performance

People are less negative about some of the specifics than they are about the package as a whole. But does this imply that those who understand the law like it better. Despite their political views, the well-informed share a strong opposition to the new law.

18 Oct 2010

Study finds vaccination rates in decline for children covered by private health plans

A new report shows that vaccination rates among two-year-olds covered by private insurance plans dipped by almost four percentage points last year." At the same time, vaccination rates for children covered by Medicaid were edging up by less than 1%.

15 Oct 2010

High Court to hear vaccine case

The New York Times: A Supreme Court case scheduled for today will examine whether the 1986 National Childhood Vaccine Injury Act should protect manufacturers from "virtually all product liability lawsuits."

13 Oct 2010

Vaccine lawsuits – Justices divided

The US Supreme Court is seemingly divided over the lawsuits on childhood vaccines. The Justices acquiesced that the Congress has done its bit to shield vaccine-makers from suits by the few who have had an adverse reaction to a vaccine approved by the Food and Drug Administration. Now the matter revolves around whether those hurt by vaccines have the right to sue manufacturers if they can prove that a safer version was available.

12 Oct 2010

New approach method could simplify study and treatment of human diseases

Therapeutic antibodies can be an efficient alternative when common drugs do not work anymore. However, antibodies obtained from blood of animals such as mice could not be used: The human immune system recognizes them as foreign and rejects them.

6 Oct 2010

Data shows Take Care Clinics’ quality of care exceeds national benchmarks

Take Care Health Systems, a wholly-owned subsidiary of Walgreens and the nation's largest and most comprehensive manager of convenient care clinics and worksite health and wellness centers, today announced that an analysis of de-identified data collected through the company's electronic medical record (EMR) system by the Jefferson School of Population Health showed that the quality of care delivered in Take Care Clinics for treatment of pharyngitis (inflammation of the throat) and upper respiratory infections (URI) meets or exceeds the quality of the care delivered in other settings.

5 Oct 2010

Outbreak of whooping cough mirrors challenges in developing world, global health official says

The outbreak of whooping cough in Texas, California, and other states this year underscores the critical importance of widespread vaccination coverage, both locally as well as around the world, said a leading global health official attending conferences on world affairs and immunization in Fort Worth this week.

29 Sep 2010

Eastmont Community Center launches new adolescent immunization awareness initiative

Eastmont Community Center responded today to alarmingly low whooping cough and meningococcal meningitis immunization rates among Latino adolescents by launching a new adolescent immunization awareness initiative. The grassroots campaign aims to educate local Latino families about free or low-cost vaccines available to help protect children against these and other infectious diseases.

24 Sep 2010

Whooping cough on the rise in California

Whooping cough is on the rise in California and the number infected has reached a 55-year high, including nine infant deaths, eight of them Hispanics. There have been more than 4,000 confirmed, probable or suspected cases this year, the most reported since 1955.

19 Sep 2010

Walgreens pharmacists in California offer immunizations that protect against pertussis

With the state of California on pace for the worst epidemic of pertussis, or whooping cough, in nearly five decades, officials from the Centers for Disease Control and Prevention as well as the California Department of Public Health continue to strongly encourage vaccination to help increase immunity and stop the spread of the disease for all Californians.

18 Sep 2010

Reuters examines conditional cash transfer programs in Latin America

Reuters examines a program providing cash incentives to "more than 2.6 million Colombians, mostly women with young children living in extreme poverty" in exchange for their participation in "health workshops" and their commitment to ensuring their children receive "regular medical check-ups," receive immunizations and "attend school at least 80 percent of the time."

16 Sep 2010

Doctors demonstrate the true impact of vaccination

With Children Back in School, Doctors Clear up Confusion and Demonstrate the True Impact of Vaccination