Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

UC San Diego researchers identify new therapeutic approach to kill cancer cells

Epithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer therapies and to become highly metastatic.

22 Aug 2019

Research explains why many psychiatric drugs that work in the lab don’t work in people

Current drug development for neuropsychiatric disorders is in crisis, say experts. More than 90 percent of all drugs that are developed for illnesses like schizophrenia, depression, Alzheimer’s disease (AD), or the brain tumor glioblastoma complete successful trials in mice but then come to a grinding halt in human trials, wasting billions of dollars in drug research. This is partly because of obvious behavioral differences between the two species.

22 Aug 2019

UCI study finds link between brain immune cells and Alzheimer's disease development

Scientists from the University of California, Irvine School of Biological Sciences have discovered how to forestall Alzheimer's disease in a laboratory setting, a finding that could one day help in devising targeted drugs that prevent it.

21 Aug 2019

Swallowable balloon device for early detection of Barrett's esophagus receives FDA 510K clearance

Investigators at Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center developed the test for early detection of Barrett's esophagus that offers promise for preventing deaths from esophageal adenocarcinoma.

21 Aug 2019

Scientists identify specific gene that plays key role in several psychiatric conditions

Scientists have identified a specific gene they believe could be a key player in the changes in brain structure seen in several psychiatric conditions, such as schizophrenia and autism.

21 Aug 2019

New lab-on-a-chip could help development of novel anti-clotting therapies

A tiny lab the size of a postage stamp could be the next big thing in the search for safer anti-clotting drugs to prevent heart attacks and strokes.

21 Aug 2019

Changes to mitochondria drive inflammation in type 2 diabetes, not glucose

To date, the underlying causes of inflammation in obesity and type 2 diabetes mellitus have been poorly understood, which has hampered efforts to develop treatments to prevent complications from a disease that is the third leading cause of death in the United States.

21 Aug 2019

Middle-life hypertension may shrink the brain in later life

A long-running study which ha been following up people into their seventies concludes that high blood pressure between the age of 36 and 53 years is associated with brain pathology such as white matter lesions and brain shrinkage in later life. To prevent this, blood pressure should be monitored beginning at or before 40 years, suggest the researchers.

21 Aug 2019

Investigating organ crosstalk leads to a better understanding of sepsis

Sepsis, a complex systemic response to infection leading to organ failure, is generally studied at the level of individual organs; this research has hinted at altered metabolic changes.

20 Aug 2019

Study: Blocking inflammatory pathway could prevent melanoma brain metastasis

Brain metastases are among the deadliest tumor metastases, with a median survival period of less than one year, and the incidence of brain metastasis is rising.

20 Aug 2019

SLU researchers receive $2.1 million to find non-addictive pain medications

Neuropathic pain affects between 15 and 20 million people in the U.S. This type of pain can occur after injuries to the nervous system due to trauma, disease or exposure to neurotoxins, including after chemotherapy.

19 Aug 2019

Researchers identify new transmembrane protein as chloride ion channel

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems.

14 Aug 2019

Beta amyloid structure mapped in new Alzheimer’s research

In search of a possible cure for Alzheimer’s disease (AD), scientists have found out the molecular structure of a type of protein called beta amyloid that accumulates within brain cells, eventually killing them. This could help understand how to prevent these abnormal proteins from forming, leading to a cure or treatment for this killer disease.

13 Aug 2019

Researchers describe histological features of urinary obstruction in humans for the first time

A research group from the Medical University of Vienna has successfully described the histological features of urinary obstruction in humans the first time.

13 Aug 2019

Study highlights how high fat diet affects one component of gut immune system

Researchers have discovered how our choice of diet can weaken our gut immune system and lead to the development of diabetes.

13 Aug 2019

Researchers identify alternate chemistry that could account for Alzheimer's pathologies

Alzheimer's disease, the most common cause of dementia among the elderly, is characterized by plaques and tangles in the brain, with most efforts at finding a cure focused on these abnormal structures.

13 Aug 2019

SU2C Dream Team to develop new drug combination to stop spread of breast cancer

At a press conference at McGill University today, Stand Up To Cancer Canada, the Canadian Cancer Society, and the Canadian Institutes of Health Research announced the launch of the SU2C Canada Metastatic Breast Cancer Dream Team to pursue the development of a new drug combination that may help stop the spread of breast cancer to other organs of the body.

13 Aug 2019