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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

COVID-19 during pregnancy may induce fetal immune response even in the absence of placental infection

SARS-CoV-2 infection during pregnancy may cause inflammatory immune responses in the fetus, even if the virus does not infect the placenta, according to a small National Institutes of Health study.

18 Jan 2022

New perspective on SARS-CoV-2 breakthrough infections and booster shot restoration of vaccine efficacy

A recent article published in the journal Science explains how SARS-CoV-2 variants can bypass vaccine-induced immune defenses. However, immunity is restorable with a booster shot. The paper's authors outlined the importance of a booster shot in maintaining immunity and preventing severe infection.

18 Jan 2022

Chinese scientists reveal key role of lysosome cell death regulator in lung tumor survival

Chinese scientists recently reported the key role of histone acetylation-regulated long noncoding RNA termed as lysosome cell death regulator (LCDR) in tumor survival, providing a potential diagnostic and therapeutic target for lung cancer.

18 Jan 2022

Analyzing disease severity of SARS-CoV-2 Omicron variant using RNA dependent RNA polymerase target delay

In a new study, a team of researchers compared the severity of the SARS-CoV-2 Omicron variant to the Delta variant using the PCR proxy marker of RNA dependent RNA polymerase target delay.

18 Jan 2022

Exploring the viral dynamics of SARS-CoV-2 Omicron variant

In a new study, researchers posted findings in which they investigated the viral dynamics of the SARS-CoV-2 Omicron variant.

18 Jan 2022

Direct effect of SARS-CoV-2 on the kidney

Researchers infected human-induced pluripotent-stem-cell (iPSC)-derived kidney organoids with SARS-CoV-2 to study the virus's direct effect on the kidney.

18 Jan 2022

SARS-CoV-2 protein biosensor employing colloidal quantum dots-modified electrode

An all-solid-state SARS-CoV-2 protein biosensor using lead sulfide colloidal quantum dots--modified electrode is demonstrated in this study by a group of researchers from several institutions.

18 Jan 2022

Applications of bioconjugated nanomaterials in SARS-CoV-2 diagnostics

In this study, the researchers not only elucidate the recent bioconjugated nanomaterials for targeted diagnosis of SARS-CoV-2, but they also provide the rationale behind these developments by discussing the mechanisms and approaches.

18 Jan 2022

Sniffer dogs detect long COVID after 1.5 years

Researchers used sniffer dogs to test the presence of SARS-CoV-2 infection in axillary sweat samples of long COVID-19 patients.

17 Jan 2022

Study suggests vaccinated Omicron cases are unlikely to shed infectious virus 10 days after diagnosis or symptom onset

Researchers have been investigating the Omicron epidemic in Japan and have recently released an early report on the infectious period of the disease.

17 Jan 2022

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

17 Jan 2022

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

A new paper discusses the appearance of quasi-species in a single host with prolonged infection, with different rates of infectivity and sensitivity to neutralization by antibodies elicited by the Pfizer vaccine or those present in convalescent plasma.

17 Jan 2022

Monitoring rodents for SARS-CoV-2 and other coronaviruses, Hong Kong

A new study published in the Centers for Disease Control and Prevention’s Emerging Infectious Diseases journal has hypothesized that locations with positive SARS-CoV-2 in sewage could be used as potential surveillance targets to analyze if pestiferous urban rodents shed SARS-CoV-2 into the environment.

16 Jan 2022

SARS-CoV-2 Omicron has similar infectious viral load to Delta

Researchers compare SARS-CoV-2 pre-variants of concern strains to the Delta and Omicron VOCs.

16 Jan 2022

Asymptomatic COVID-19 patients less infectious than symptomatic patients

Researchers investigate the progression of infection in students and employees who tested positive for SARS-CoV-2 at Boston University.

16 Jan 2022

Study reveals factors responsible for increased risk of aerosol transmission for SARS-CoV-2 Delta and Omicron

A new study describes the expected distribution of viral emission of COVID-19 by an infected population of people who were either silent, speaking softly, or loudly, to determine factors influencing risks of viral transmission.

14 Jan 2022

Similarities and dissimilarities in immune responses and metabolism in SARS-CoV-2 and HIV-1 infections

A new study, posted to the bioRxiv* preprint server, has developed a single-cell atlas that presents the shared and distinct immune responses and metabolism following SARS-CoV-2 and HIV-1 infections.

13 Jan 2022

BNT162b2 COVID vaccine 94% effective against adolescent hospitalization

A recent study revealed the effectiveness of 93% for the BNT162b2 vaccine against COVID-19 hospitalization among adolescents (12 to 18 years). This study included 179 patients at 19 sites in 16 states. The same group of researchers have extended their analysis to 31 locations in 23 states across the U.S. and recruited 266 more patients who had been hospitalized with SARS-CoV-2 infection.

13 Jan 2022

Investigating the presence of human rRNA in the SARS-CoV-2 genome

In a new study, a team of researchers investigated the existence of SARS-CoV-2-host chimeric RNA and described two novel human-derived genomic insertions present in the circulating variants of SARS-CoV-2.

13 Jan 2022

Plasma SARS-CoV-2 viral RNA as a valuable biomarker for SARS-CoV-2 infection in the lungs

Researchers recently evaluated respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA (vRNA) levels in longitudinal samples collected simultaneously from mechanically ventilated coronavirus disease 2019 (COVID-19) patients and analyzed their connections and relationships with clinical outcomes.

13 Jan 2022

RNA News and Research

Further Reading

COVID-19 during pregnancy may induce fetal immune response even in the absence of placental infection

New perspective on SARS-CoV-2 breakthrough infections and booster shot restoration of vaccine efficacy

Chinese scientists reveal key role of lysosome cell death regulator in lung tumor survival

Analyzing disease severity of SARS-CoV-2 Omicron variant using RNA dependent RNA polymerase target delay

Exploring the viral dynamics of SARS-CoV-2 Omicron variant

Direct effect of SARS-CoV-2 on the kidney

SARS-CoV-2 protein biosensor employing colloidal quantum dots-modified electrode

Applications of bioconjugated nanomaterials in SARS-CoV-2 diagnostics

Sniffer dogs detect long COVID after 1.5 years

Study suggests vaccinated Omicron cases are unlikely to shed infectious virus 10 days after diagnosis or symptom onset

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

Monitoring rodents for SARS-CoV-2 and other coronaviruses, Hong Kong

SARS-CoV-2 Omicron has similar infectious viral load to Delta

Asymptomatic COVID-19 patients less infectious than symptomatic patients

Study reveals factors responsible for increased risk of aerosol transmission for SARS-CoV-2 Delta and Omicron

Similarities and dissimilarities in immune responses and metabolism in SARS-CoV-2 and HIV-1 infections

BNT162b2 COVID vaccine 94% effective against adolescent hospitalization

Investigating the presence of human rRNA in the SARS-CoV-2 genome

Plasma SARS-CoV-2 viral RNA as a valuable biomarker for SARS-CoV-2 infection in the lungs

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