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Novel compound amplifies naloxone's power to reverse overdoses

In a Stanford Medicine-led study, researchers combed through billions of compounds to find one that could enhance naloxone’s ability to fend off more potent opioids, with promising results in mice.

4 Jul 2024

Study suggests gastric bypass can reduce cardiovascular disease risk, irrespective of weight loss

Researchers investigated whether Roux-en-Y gastric bypass reduces cardiovascular risk factors independent of calorie restriction and weight loss.

4 Jul 2024

Repurposing cancer drug to prevent organ damage in infectious diseases

Twelve years ago, cancer researchers at University of California San Diego identified a molecule that helps cancer cells survive by shuttling damaging inflammatory cells into tumor tissue.

3 Jul 2024

Single-cell profiling of lateral septum neurons reveals LSEsr1's role in METH addiction

Recently, a research team led by Dr. ZHU Yingjie from the Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences has published a study in Neuron, the study presents a comprehensive transcriptional profile of the lateral septum (LS) at the single-cell level, elucidating the spatial distribution of its major neuronal types.

3 Jul 2024

Monocyte signature predicts dexamethasone response in severe COVID-19 patients

Dexamethasone is one of the most important drugs in the treatment of severe COVID-19, but patients respond very differently to the therapy.

3 Jul 2024

Researchers identify potential drugs that make naloxone more potent and longer lasting

The ongoing opioid epidemic in the U.S. kills tens of thousands of people every year. Naloxone, sold under the brand name Narcan, has saved countless lives by reversing opioid overdoses.

3 Jul 2024

New research highlights potential of antimicrobial peptide mixtures to inhibit drug resistance

Antibiotics are a cornerstone of modern medicine. They are regularly used to treat bacterial infections or as a prophylactic measure during surgery to prevent infection.

3 Jul 2024

Protein nanocages: A promising frontier in mRNA therapeutics

In recent years, messenger RNA (mRNA) has emerged as a promising avenue for accurate and potent therapeutic interventions. Unlike DNA drugs, mRNA can express genetic information without the risk of integrating into the host genome.

3 Jul 2024

KFF Health News' 'What the Health?': SCOTUS term wraps with a bang

It was a busy year for health-related cases at the Supreme Court. Among other issues, the justices grappled with two abortion cases, a separate case touching on the opioid epidemic, and a case challenging whether localities can bar homeless people from sleeping in public spaces.

3 Jul 2024

Research could help drug developers improve the safety profiles of medications

Research from the University of British Columbia, MIT, and the University of Michigan could help drug developers improve the safety profiles of medications and reduce side effects.

3 Jul 2024

Lack of affordability tops older Americans’ list of health care worries

What weighs most heavily on older adults' minds when it comes to health care?

3 Jul 2024

Decoding the significance of subnormal liver enzyme activity

Liver diseases are commonly diagnosed using serum enzyme assays, particularly for aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT), and 5'-nucleotidase (5'-NT).

3 Jul 2024

Ribosomes and ZAK protein spur the cell's initial response to UV radiation damage

In a recent study, researchers at Johns Hopkins Medicine suggest the cell's messenger RNA (mRNA) - the major translator and regulator of genetic material - along with a critical protein called ZAK, spur the cell's initial response to UV radiation damage and play a critical role in whether the cell lives or dies.

2 Jul 2024

SRI’s novel injectable formulation aims to provide a better option to fight malaria

SRI today announced that researchers are developing a new treatment that aims to provide a better option to fight malaria, particularly for people in low-income and rural regions.

2 Jul 2024

Antimicrobial peptide mixtures: A viable approach to long-lasting antibiotic treatments

A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather than a single peptide, making these mixtures a viable strategy for developing new antibiotic treatments.

2 Jul 2024

GCARDTI: Advancing drug-target interaction prediction with hybrid graph learning

The identification of drug-target Interactions (DTIs) represents a pivotal link in the process of drug development and design.

2 Jul 2024

Welch Foundation funds UTA’s research into creating new materials for effective drug delivery

With a $300,000 grant, the Welch Foundation is supporting University of Texas at Arlington research into creating new materials to safely and effectively deliver medications to treat diseases such as cancer.

2 Jul 2024

Study finds promising new target for the treatment of Alzheimer's disease

A class of proteins that regulates cell repair and enhances cell growth-signaling systems could be a promising new target for the treatment of Alzheimer's and other neurodegenerative diseases, according to a new study led by researchers at Penn State.

2 Jul 2024

Understanding non-drinking days may inform alcohol prevention strategies

Understanding the reasons why young adults choose not to drink on certain days may inform prevention and intervention programs aimed at reducing the harms associated with alcohol consequences.

2 Jul 2024

Visible light technique simplifies synthesis of key pharmaceutical building blocks

University of Michigan chemists have discovered a way to use visible light to synthesize a class of compounds particularly well suited for use in pharmaceuticals.

2 Jul 2024

Drugs News and Research

Novel compound amplifies naloxone's power to reverse overdoses

Study suggests gastric bypass can reduce cardiovascular disease risk, irrespective of weight loss

Repurposing cancer drug to prevent organ damage in infectious diseases

Single-cell profiling of lateral septum neurons reveals LSEsr1's role in METH addiction

Monocyte signature predicts dexamethasone response in severe COVID-19 patients

Researchers identify potential drugs that make naloxone more potent and longer lasting

New research highlights potential of antimicrobial peptide mixtures to inhibit drug resistance

Protein nanocages: A promising frontier in mRNA therapeutics

KFF Health News' 'What the Health?': SCOTUS term wraps with a bang

Research could help drug developers improve the safety profiles of medications

Lack of affordability tops older Americans’ list of health care worries

Decoding the significance of subnormal liver enzyme activity

Ribosomes and ZAK protein spur the cell's initial response to UV radiation damage

SRI’s novel injectable formulation aims to provide a better option to fight malaria

Antimicrobial peptide mixtures: A viable approach to long-lasting antibiotic treatments

GCARDTI: Advancing drug-target interaction prediction with hybrid graph learning

Welch Foundation funds UTA’s research into creating new materials for effective drug delivery

Study finds promising new target for the treatment of Alzheimer's disease

Understanding non-drinking days may inform alcohol prevention strategies

Visible light technique simplifies synthesis of key pharmaceutical building blocks

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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