Genome News and Research

RSS

Study finds SARS-CoV-2 infection caused significant changes in the levels of stress associated small RNAs

In this study, researchers described the effect of significant changes of small RNAs in the post-transcriptional regulatory network.

13 Jan 2022

Ultra-rapid genome sequencing technology can detect rare genetic diseases in eight hours

A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators was used to diagnose rare genetic diseases in an average of eight hours - a feat that's nearly unheard of in standard clinical care.

13 Jan 2022

The unique T cell response elicited by SARS-CoV-2 during a primary immune response by infection and vaccination

The distinctive characteristics of the T cell response generated by SARS-CoV-2 infection and vaccination and the relationship to CCCoVs and VOC was explored in a review published in Frontiers in Medicine.

13 Jan 2022

The Native Antigen Company Expands Range of Norovirus-Like Particles

The Native Antigen Company today announced the expansion of its norovirus-like particle range, with the addition of six new reagents.

From The Native Antigen Company 13 Jan 2022

The zoonotic potential of epidemic porcine deltacoronavirus

The present state of knowledge about the genesis, evolution, cross-species transmission, and zoonotic potential of PDCoV is the subject of a review published in the journal Pathogens, which was conducted in a combined effort by researchers from Heilongjiang Bayi Agricultural University and Ohio State University.

13 Jan 2022

Dynamics of hospital-acquired SARS-CoV-2 infection in a geriatric setting

Researchers investigated the extent of nosocomial SARS-CoV-2 infection among elderly patients and healthcare workers in a geriatric hospital.

12 Jan 2022

New method for monitoring circulating SARS-CoV-2 variants and detecting new ones

To understand and act early and appropriately to emerging variants of concern, researchers have explored the possibility of having a variant-agnostic detection assay.

12 Jan 2022

MAPK4 may play a key role in triple-negative breast cancer

Scientific evidence supporting the involvement of the enzyme MAPK4 in cancer growth and resistance to certain therapies has been growing quickly.

12 Jan 2022

AI-driven solution predicts RNA and DNA binding sites to accelerate rational drug discovery

The iMolecule group from Skoltech has developed an artificial intelligence-driven solution that uses data on the structure of RNA or DNA molecules to identify sites on them where interaction with potential drug candidates can occur.

11 Jan 2022

Study opens up prospects for using virotherapy to treat central nervous system tumors

In a study conducted at the University of São Paulo's Human Genome and Stem Cell Research Center (HUG-CELL) in Brazil, serial systemic injections of zika virus into mice with brain tumors destroyed the cancer without causing neurological damage or injuring other organs, and increased the animals' survival rate.

11 Jan 2022

VarLOCK approach for rapid detection of SARS-CoV-2 variants of concern and wastewater monitoring

A recent study discussed the expansion of the SARS-CoV-2 CRISPR-Cas detection technology (SHERLOCK) into Variant-specific SHERLOCK (VarLOCK) assays to accurately differentiate between the newly emerging SARS-CoV-2 variants of concern.

11 Jan 2022

Study reveals genomic regions that could help understand obesity

A new study has helped to shine light on the genetic pathways underlying obesity. The findings could help develop more personalized ways to help people maintain a healthy weight.

11 Jan 2022

COVID-19 symptoms found to vary in different immune contexts

In a new study, researchers studied the kinetics of host response to SARS-CoV-2 infection in a Syrian hamster model, tracking disease pathology, viral loads, antibody responses, and inflammatory cytokine production in multiple organs.

11 Jan 2022

Analyzing the evolution of SARS-CoV-2 RNA polymerase in humans

In a new study, researchers examined the impact of mutations on the structural thermodynamic stability (structural stability) of SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) through free energy computation.

11 Jan 2022

Single-step RT-PCR for SARS-CoV-2 Omicron variant detection in respiratory samples

A new preprint describes a single-step molecular diagnostic test for the presence of SARS-CoV-2 infection caused by the Omicron variant that is behind the unprecedented rise in cases over the last few weeks.

11 Jan 2022

Newly developed risk scores can help identify childhood obesity risk

Newly developed risk scores synthesize genetic information into an easy-to-interpret metric that could help clinicians identify young children most at risk of developing obesity.

10 Jan 2022

Researchers illuminate the molecular landscape and clinical features of rare kidney cancer

Translocation renal cell carcinoma (tRCC) is a rare and aggressive form of kidney cancer. It accounts for about 5 percent of all renal cell carcinomas in adults and about 50 percent in children.

10 Jan 2022

SARS-CoV-2 spike engagement of ACE2 shown to prime S2′ site cleavage and fusion initiation

In a new study, researchers used a cell-cell fusion assay to extract potentially cleaved spike protein products from syncytia in order to explore the functional and biochemical characteristics of spike (S) protein when it engages its receptor ACE2 in living cells.

10 Jan 2022

New lab-on-a-chip platform for detecting SARS-CoV-2 in resource-limited settings

A recent study shows how a novel and integrated lab-on-a-chip platform can represent a rapid, affordable, and exact molecular diagnostic tool for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The paper is currently available for free on the medRxiv* preprint server while it undergoes peer review.

9 Jan 2022

Emerging SARS-CoV-2 B.1.619 and B.1.620 variants in South Korea

Researchers investigate the spread and transmission ability of SARS-CoV-2 lineages B.1.619 and B.1.620 in South Korea.

9 Jan 2022

Genome News and Research

Study finds SARS-CoV-2 infection caused significant changes in the levels of stress associated small RNAs

Ultra-rapid genome sequencing technology can detect rare genetic diseases in eight hours

The unique T cell response elicited by SARS-CoV-2 during a primary immune response by infection and vaccination

The Native Antigen Company Expands Range of Norovirus-Like Particles

The zoonotic potential of epidemic porcine deltacoronavirus

Dynamics of hospital-acquired SARS-CoV-2 infection in a geriatric setting

New method for monitoring circulating SARS-CoV-2 variants and detecting new ones

MAPK4 may play a key role in triple-negative breast cancer

AI-driven solution predicts RNA and DNA binding sites to accelerate rational drug discovery

Study opens up prospects for using virotherapy to treat central nervous system tumors

VarLOCK approach for rapid detection of SARS-CoV-2 variants of concern and wastewater monitoring

Study reveals genomic regions that could help understand obesity

COVID-19 symptoms found to vary in different immune contexts

Analyzing the evolution of SARS-CoV-2 RNA polymerase in humans

Single-step RT-PCR for SARS-CoV-2 Omicron variant detection in respiratory samples

Newly developed risk scores can help identify childhood obesity risk

Researchers illuminate the molecular landscape and clinical features of rare kidney cancer

SARS-CoV-2 spike engagement of ACE2 shown to prime S2′ site cleavage and fusion initiation

New lab-on-a-chip platform for detecting SARS-CoV-2 in resource-limited settings

Emerging SARS-CoV-2 B.1.619 and B.1.620 variants in South Korea

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

Latest News