Therapy News and Research

RSS

Simple dietary supplement may provide new approach to boost CAR T cell cancer-fighting power

A simple dietary supplement may provide a new approach to boost CAR T cell function, according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

9 Dec 2024

Breakthrough treatment improves survival rates for children with B-ALL

Just days before his fourth birthday, Santiago was diagnosed with B-cell acute lymphoblastic leukemia (B-ALL), the most common cancer in children.

9 Dec 2024

Early bilateral oophorectomy linked to increased Alzheimer's disease risk

Women with early bilateral oophorectomy face higher Alzheimer's risk, especially with APOE4 allele; education and hormone therapy may offer resilience.

9 Dec 2024

Depression genes amplify women's heart disease risk

Study reveals a sex-specific link between genetic risks for psychiatric disorders and cardiovascular diseases (CVDs), with women showing a higher risk of atrial fibrillation, coronary artery disease, and heart failure linked to genetic predisposition to major depression. Menopause and modifiable factors like BMI and smoking amplify these risks.

8 Dec 2024

Filgotinib offers new promise for managing Crohn’s disease

Filgotinib, a JAK1 preferential inhibitor, shows promise as an effective and well-tolerated maintenance therapy for Crohn's disease, achieving clinical and endoscopic remission in phase 3 trials. The findings highlight its potential as a novel therapeutic option for difficult-to-treat patients.

8 Dec 2024

$1.5 million grant supports alternatives to opioids initiative at University Hospitals

A grant of nearly $1.5 million from the Department of Health and Human Services through its Substance Abuse and Mental Health Services Administration (SAMHSA) will enable University Hospitals Cleveland Medical Center to develop and implement an Alternatives to Opioids (ALTO) program within its Emergency Department (ED).

6 Dec 2024

New insights into the mechanisms of "Niemann-Pick type C" in children

In the journal "Science Translational Medicine", scientists from DZNE and LMU Hospital report on new insights into the mechanisms of "Niemann-Pick type C" (NPC), a rare neurodegenerative disease associated with dementia that can manifest as early as childhood.

6 Dec 2024

Dual-antibody therapy shows promise in treating metastatic colorectal cancer

Metastatic colorectal cancer (mCRC) remains a daunting challenge, especially after first-line treatments fail.

6 Dec 2024

New technology guides immune cells to fight brain cancer and multiple sclerosis

Researchers have found a way to program immune cells to attack glioblastoma and treat the inflammation of multiple sclerosis in mice.

6 Dec 2024

MDMA's potential to improve therapeutic outcomes in military neurorehabilitation

A UCLA Health analysis of MDMA-assisted therapy research suggests that the drug could improve outcomes of treatment of a wider range of trauma-related conditions experienced by military personnel beyond the current focus on post-traumatic stress disorder (PTSD) by increasing a collaborative and trusting relationship between a client and therapist.

6 Dec 2024

Antidepressant use linked to persistent genital sensitivity loss

The use of antidepressants is associated with sexual side effects including reduced genital sensitivity that persists after stopping the medication, a new Simon Fraser University study finds.

6 Dec 2024

Psilocybin helps reduce depression in clinicians amid COVID-19 crisis

Psilocybin-assisted psychotherapy resulted in significant reductions in depression among clinicians who provided front-line COVID-19 care in 2020 and 2021.

5 Dec 2024

EZH2 inhibitors enhance effectiveness of cancer immunotherapies

An emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of some cancer immunotherapies, according to a preclinical study led by Weill Cornell Medicine lymphoma researchers.

5 Dec 2024

Early ovarian removal and APOE4 increase Alzheimer's risk in women

New research published by a team of researchers from the University of Toronto in collaboration with colleagues from the University of Alberta has found that women who have had both ovaries surgically removed before the age of 50 and carry a variant of the apolipoprotein gene, the APOE4 allele, are at high risk of late-life Alzheimer disease (AD). Use of hormone therapy mitigates this risk.

5 Dec 2024

Scientists link proteins to Alzheimer’s through cutting-edge genetic method

Researchers have developed MR-SPI, a novel method integrated with AlphaFold3, to identify causal protein biomarkers and predict their 3D structural changes in Alzheimer’s disease. This breakthrough offers insights into disease mechanisms and potential therapeutic targets.

5 Dec 2024

Dupilumab improves symptoms of atopic dermatitis in children with co-existing conditions

Research at National Jewish Health and other institutions has shown that the biologic dupilumab improves signs and symptoms of moderate-to-severe atopic dermatitis (eczema) in young children whether or not they have another inflammatory condition, such as asthma, allergic rhinitis or food allergies.

5 Dec 2024