Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Brazilian scientists examine how benzopyrene can cause cancer

Benzo[a]pyrene is a potent carcinogen and mutagen present in cigarette smoke, automotive exhaust, burnt wood fumes, barbecued and smoked meat etc.

23 Oct 2017

Researchers discover new regulatory role for protein that links diet and disease

A team of researchers from Case Western Reserve University School of Medicine have discovered how uncontrolled vitamin A metabolism in the gut can cause harmful inflammation.

23 Oct 2017

Queen's University Belfast leads new research to better understand biology of prostate cancer

Queen's University Belfast has led the world's largest research study using a diagnostic test developed by Almac Diagnostics, to better understand the biology of prostate cancer tumors, which could lead to a transformation in how prostate cancer is diagnosed and treated.

23 Oct 2017

Gene circuit can be used to switch on inside cancer cells and stimulate immune attack, study suggests

A new study, conducted by researchers at MIT, suggests that a recently developed synthetic gene circuit can stimulate the immune system to kill cancer cells when it identifies indications of the cancer. The gene circuit will only stimulate a therapeutic response when it identifies two particular cancer markers.

20 Oct 2017

Better post-weaning diet can reverse potential consequences of early-life high-fat exposure

Research has shown that a mother's diet during pregnancy, particularly one that is high-fat, may program her baby for future risk of certain diseases such as diabetes. A new study from nutrition researchers at the University of Illinois shows that switching the offspring to a new diet--a low-fat diet, in this case--can reverse that programming.

20 Oct 2017

New study describes how gene-environment interaction leads to congenital heart defects

Infants of mothers with diabetes have a three- to five-fold increased risk of congenital heart defects. Such developmental defects are likely caused by a combination of genetic and environmental factors.

19 Oct 2017

New RNA switch achieves gene activation thousands of times better than nature

If scientists could precisely regulate gene expression, they could turn off the genes responsible for illness and disease and turn on those that enhance health and the immune system.

19 Oct 2017

Novel gene expression signature assay could help enhance lymphoma management

Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer and the most frequently diagnosed non-Hodgkin lymphoma worldwide (nearly 40% of cases). Recent advancements indicate that both the prognosis and choice of treatment of DLBCL may depend on identifying its molecular subtype.

17 Oct 2017

Dietary combination transforms lethal breast cancers into highly treatable form

Researchers at the University of Alabama at Birmingham have found a dietary combination that transforms the most lethal of all breast cancers into a highly treatable breast cancer.

17 Oct 2017

Scientists discover new non-genetic cause of resistance to anti-cancer therapies

The targeted anti-cancer therapies cetuximab and panitumumab are mainstays of treatment for advanced colorectal cancer, the second leading cause of cancer-related deaths in the United States.

16 Oct 2017

Findings reveal how seizures can have lasting detrimental effects on memory

Although it's been clear that seizures are linked to memory loss and other cognitive deficits in patients with Alzheimer's disease, how this happens has been puzzling. In a study published in the journal Nature Medicine, a team of researchers reveals a mechanism that can explain how even relatively infrequent seizures can lead to long-lasting cognitive deficits in animal models.

16 Oct 2017

New study maps human genome to healthy tissue functions and disease processes

Our genomes help to determine who we are - the countless variations between individuals that encode the complexity of tissues and functions throughout the body.

13 Oct 2017

TGen awarded $2.5 million SU2C grant to test new method of treating pancreatic cancer

Stand Up To Cancer has awarded a $2.5 million SU2C CatalystR grant to the Translational Genomics Research Institute to investigate a revolutionary new method of treating pancreatic cancer, one of the most aggressive of all cancers.

13 Oct 2017

Specific regions of silenced DNA help define cell's identity, study suggests

The fundamental mechanisms governing how cells form an identity such as becoming a muscle cell or a nerve cell are not fully understood. Multiple diseases, including cancer, have been linked to cells going down the wrong developmental path during maturation.

13 Oct 2017

Salk scientists receive $2.5 million funding to conduct pancreatic cancer clinical study

Salk Professor and HHMI Investigator Ronald Evans has been awarded $2.5 million by Stand Up 2 Cancer (SU2C) as part of a multi-institution team to conduct clinical studies to open up a new avenue for immunotherapy in the treatment of pancreatic cancer.

12 Oct 2017

New computer program identifies different cell types based on gene expression patterns

"How many different cell types are there in a human body? And how do these differences develop? Nobody really knows," says Professor Stein Aerts from KU Leuven and VIB, Belgium. But thanks to a new method developed by his team, that may be about to change.

10 Oct 2017

Penn Medicine professor receives New Innovator Award from NIH

Hao Wu, PhD, an assistant professor of Genetics in the Perelman School of Medicine at the University of Pennsylvania has received a New Innovator Award from the National Institutes of Health. These awards provide each recipient $1.5 million over five years to pursue high-risk, high-reward investigations that could have implications for human health.

9 Oct 2017

Researchers develop new diagnostic and prognosis method for early detection of liver cancer

An international team of researchers at University of California San Diego School of Medicine and Moores Cancer Center, with colleagues at Sun Yet-sun University Cancer Center and other collaborating institutions, have developed a new diagnostic and prognosis method for early detection of hepatocellular carcinoma (HCC), based on a simple blood sample containing circulating tumor DNA.

9 Oct 2017

Change in epigenetic gene regulation by imprinting can trigger preeclampsia, study shows

Preeclampsia is the most dangerous form of hypertension during a pregnancy and can be fatal for both mother and child. Though it is known to originate in the placenta, the root causes remain largely a mystery.

6 Oct 2017

Researchers uncover promising targets for development of drugs against leishmaniasis

Brazilian researchers at the University of São Paulo's Bioscience Institute (IB-USP) are starting to unravel the molecular mechanisms by which the parasite that causes cutaneous leishmaniasis manages to circumvent the host organism's defenses and infect new cells.

5 Oct 2017

Gene Expression News and Research

Further Reading

Brazilian scientists examine how benzopyrene can cause cancer

Researchers discover new regulatory role for protein that links diet and disease

Queen's University Belfast leads new research to better understand biology of prostate cancer

Gene circuit can be used to switch on inside cancer cells and stimulate immune attack, study suggests

Better post-weaning diet can reverse potential consequences of early-life high-fat exposure

New study describes how gene-environment interaction leads to congenital heart defects

New RNA switch achieves gene activation thousands of times better than nature

Novel gene expression signature assay could help enhance lymphoma management

Dietary combination transforms lethal breast cancers into highly treatable form

Scientists discover new non-genetic cause of resistance to anti-cancer therapies

Findings reveal how seizures can have lasting detrimental effects on memory

New study maps human genome to healthy tissue functions and disease processes

TGen awarded $2.5 million SU2C grant to test new method of treating pancreatic cancer

Specific regions of silenced DNA help define cell's identity, study suggests

Salk scientists receive $2.5 million funding to conduct pancreatic cancer clinical study

New computer program identifies different cell types based on gene expression patterns

Penn Medicine professor receives New Innovator Award from NIH

Researchers develop new diagnostic and prognosis method for early detection of liver cancer

Change in epigenetic gene regulation by imprinting can trigger preeclampsia, study shows

Researchers uncover promising targets for development of drugs against leishmaniasis

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