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FDA-approved Alzheimer's drug induces torpor-like state in tadpoles

Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University report that they were able to successfully put tadpoles of Xenopus laevis frogs into a hibernation-like torpor state using donepezil (DNP), a drug approved by the FDA to treat Alzheimer’s.

27 Aug 2024

Feds killed plan to curb Medicare Advantage overbilling after industry opposition

A decade ago, federal officials drafted a plan to discourage Medicare Advantage health insurers from overcharging the government by billions of dollars — only to abruptly back off amid an "uproar" from the industry, newly released court filings show.

27 Aug 2024

Semaglutide shown to cut major adverse cardiovascular events in heart failure patients

Semaglutide shows promise in reducing cardiovascular risks in obese patients with heart failure, improving outcomes in a recent large-scale clinical trial.

27 Aug 2024

Dengue increases risk of heart and neurological complications compared to COVID-19

People who caught dengue and recovered are more likely to face long-term health complications about a year later compared to those who contracted COVID-19, according to the findings of a nationwide study led by Nanyang Technological University, Singapore (NTU Singapore).

27 Aug 2024

Study warns of high Medicare costs for semaglutide even with restrictive CVD definition

If Medicare Part D narrowly defines cardiovascular disease, the majority of patients would remain ineligible while new federal spending could still exceed $10 billion

27 Aug 2024

Grandparental education predicts grandchildren's biological age

Eating well, exercising and attending regular doctor appointments can support a long healthy life, but a new study identified one possible factor beyond our control: whether you had a grandparent who went to college. The study, from researchers at Drexel University and colleagues from the University of California and the University of North Carolina, was recently published in the journal Social Science and Medicine.

27 Aug 2024

Exclusive breastfeeding aids postpartum weight loss

A KK Women's and Children's Hospital (KKH) study[1] on breastfeeding practices revealed that among the women who exclusively breastfed, those with high body mass index[2] (BMI) before pregnancy lost more weight than women with a healthy BMI pre-pregnancy.

27 Aug 2024

Increased mental health risks in patients with brain aneurysms

Among people who had aneurysms (weakened areas in brain blood vessels), the risk of developing a mental health condition was higher than among peers without an aneurysm.

26 Aug 2024

Brief periods of light-intensity exercise can boost children's cerebral blood flow

Cognitive functions, also known as intellectual functions, encompass thinking, understanding, memory, language, computation, and judgment, and are performed in the cerebrum.

26 Aug 2024

Almost half of FDA-approved medical AI devices lack clinical validation data

Artificial intelligence (AI) has practically limitless applications in healthcare, ranging from auto-drafting patient messages in MyChart to optimizing organ transplantation and improving tumor removal accuracy.

26 Aug 2024

Many parents want guidance on preventing hereditary health conditions in children

Among things many families don't wish to pass down to their children and grandchildren: medical issues.

26 Aug 2024

Children and adolescents experience unique long COVID symptoms

A study characterizes childhood long COVID, revealing distinct symptoms in children and adolescents, highlighting the need for tailored diagnostic approaches.

26 Aug 2024

Gut microbe metabolite found to modulate heart disease risk through β2-adrenergic receptors

Study identifies phenylacetylglutamine (PAGln), a gut microbiome metabolite, as a novel allosteric modulator of β2-adrenergic receptors, offering insights into its role in cardiovascular disease (CVD) risk.

26 Aug 2024

Engineered human cardiac tissue reveals how lupus autoantibodies damage the heart

Study demonstrates that autoantibodies in systemic lupus erythematosus (SLE) patients contribute to myocardial injury by binding to and impairing stressed cardiac cells, offering insights into potential therapeutic targets.

25 Aug 2024

Strength training triggers key mechanisms for cellular waste clearance

The elimination of damaged cell components is essential for the maintenance of the body's tissues and organs.

23 Aug 2024

Study reveals negative health consequences of sleep disruption for overweight individuals

New research from Oregon Health & Science University reveals negative health consequences for people who are overweight and ignore their body's signals to sleep at night, with specific differences between men and women.

23 Aug 2024

Defective ZNRF3 gene causes opposing brain sizes and potential tumor risk

A gene called ZNRF3, known to be involved in cancer, also messes with the mind. The human brain relies on two copies of this gene to build a right-sized brain. If one of the copies is defective, the brain will be either too small or too large - known as mirror effect -, leading to various neurological symptoms.

23 Aug 2024

Study reveals bidirectional relationship between diabetes complications and mental health disorders

Heart attack, stroke, nerve damage. These are just some of the complications for which millions of Americans with diabetes are at greater risk.

23 Aug 2024

New evidence supports the effectiveness of thiazides for kidney stone prevention

Higher thiazide doses are associated with greater reductions in urine calcium, which in turn correlate with fewer symptomatic kidney stone events, according to a Vanderbilt University Medical Center (VUMC) study published in JAMA Network Open.

23 Aug 2024

Exploring the impact of thyroid hormone on brain function

Thyroid hormone plays a key role in regulating a range of physiologic functions, including metabolism, temperature, heart rate, and growth. It accomplishes this impressive array of activities by interacting with almost every organ system in the body. Yet despite a long history of research on how thyroid hormone influences different organs, its effects on arguably the most crucial organ - the brain - have remained shrouded in mystery.

23 Aug 2024

Heart News and Research

FDA-approved Alzheimer's drug induces torpor-like state in tadpoles

Feds killed plan to curb Medicare Advantage overbilling after industry opposition

Semaglutide shown to cut major adverse cardiovascular events in heart failure patients

Dengue increases risk of heart and neurological complications compared to COVID-19

Study warns of high Medicare costs for semaglutide even with restrictive CVD definition

Grandparental education predicts grandchildren's biological age

Exclusive breastfeeding aids postpartum weight loss

Increased mental health risks in patients with brain aneurysms

Brief periods of light-intensity exercise can boost children's cerebral blood flow

Almost half of FDA-approved medical AI devices lack clinical validation data

Many parents want guidance on preventing hereditary health conditions in children

Children and adolescents experience unique long COVID symptoms

Gut microbe metabolite found to modulate heart disease risk through β2-adrenergic receptors

Engineered human cardiac tissue reveals how lupus autoantibodies damage the heart

Strength training triggers key mechanisms for cellular waste clearance

Study reveals negative health consequences of sleep disruption for overweight individuals

Defective ZNRF3 gene causes opposing brain sizes and potential tumor risk

Study reveals bidirectional relationship between diabetes complications and mental health disorders

New evidence supports the effectiveness of thiazides for kidney stone prevention

Exploring the impact of thyroid hormone on brain function

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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