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Researchers uncover cellular resistance mechanisms to BRAF inhibitors in melanoma

Melanoma is one of the most aggressive types of skin cancer, but recent advances in targeted therapies have improved the prognosis for many patients. Unfortunately, for some patients these positive outcomes are not long lasting, due to the development of drug resistance and tumor recurrence.

15 Apr 2019

Duration of thrombectomies proves crucial in success of the procedure

The "Stroke Belt" refers to the swath of states in the Southeast where rates of stroke death are high, and according to the Department of Health and Environmental Control, South Carolina comes in at number six for the nation's highest rates of stroke death.

15 Apr 2019

Hospital ICU patients with non-brain-related injuries may have undetected cognitive deficits

A new study led by Western University and Lawson Health Research Institute has found that most patients entering hospital intensive care units (ICU) for non-brain-related injuries or ailments also suffer from some level of related cognitive dysfunction that currently goes undetected in most cases.

12 Apr 2019

New technique uses UV and red light to decontaminate organs before transplantation

A new technique for the decontamination of organs before transplantation using ultraviolet and red light irradiation has been developed by Brazilian and Canadian researchers and is described in an article published in the journal Nature Communications.

12 Apr 2019

The two-hit model can lead to better understanding of heart failure

Nearly half of current hospital admissions for heart failure are caused by a type of the disease with no treatment options. Cardiology researchers at UT Southwestern Medical Center are changing that reality with a fresh approach, recently published in Nature.

12 Apr 2019

Stimulating parvalbumin-containing cells causes surprising changes in blood volume, flow

Alzheimer's disease and schizophrenia are some of the most common brain disorders and have been associated with problems in cells that contain a type of protein, called parvalbumin.

10 Apr 2019

Testing how well wastewater disinfection methods affect antibiotic resistance genes

Each year at least 2 million Americans are infected with bacteria that cannot be treated with antibiotics, and at least 23,000 of these people die, according to the Centers for Disease Control.

9 Apr 2019

Biologists analyze available methods of targeted drug delivery to malignant tumors

A team of biologists from Sechenov First Moscow State Medical University and Lobachevsky University analyzed available methods of targeted drug delivery to malignant tumors.

9 Apr 2019

Cellular protein could take on role of restriction factor for hepatitis B virus

Hepatitis B is a viral liver infection that can lead to acute or chronic conditions. Although there is a vaccine that offers protection against the virus, current treatments which prevent the virus from replicating are not curative for infected individuals.

8 Apr 2019

Scientists solve mystery of how bacterial nanowires conduct electricity

Scientists have made a surprising discovery about how strange bacteria that live in soil and sediment can conduct electricity.

5 Apr 2019

Developing imaging techniques for early detection of eye and brain diseases

The eyes may be the window to the soul, but to scientists, they are also the window to the brain. In particular, the retina, a delicate light-sensing neural network with specialized cells at the back of the eyeball, is linked directly to the brain via the optic nerve and is considered by some to be part of the brain itself.

4 Apr 2019

Researchers use metal-free catalyst to synthesize ketone from aldehyde

Ketones are important organic compounds found in a variety of pharmaceuticals, agrochemicals, and natural products.

4 Apr 2019

Finding homeless patients a place to heal

After they amputated the second toe on John Trumbla's right foot last summer, doctors sent him to a nursing home because he still needed medical care — but not necessarily a hospital bed.

3 Apr 2019

Researchers explore better treatments for irritated tendons

When tendons get irritated it can lead to a serious condition called tendinosis -- a common class of sports and workplace injuries -- which is also common in older individuals. It can take many weeks of rest for tendon irritation to heal, with no treatments, save short-term steroid injections and surgery, followed by more rest.

3 Apr 2019

Photoacoustic microscopy helps scientists to better scrutinize cancer cells

Devising the best treatment for a patient with cancer requires doctors to know something about the traits of the cancer from which the patient is suffering.

2 Apr 2019

Study reveals new strategy to combat antibiotic resistance

A new strategy to combat antibiotic resistance has emerged from a study led by researchers at Baylor College of Medicine. Published in the journal Molecular Cell, the report reveals for the first time how bacteria evolve mutations that confer antibiotic resistance and that this process can be inhibited with FDA-approved drug edaravone.

2 Apr 2019

Maternal smoking and pre-eclampsia may affect fertility of offspring

Low levels of oxygen in the womb - which can be caused by smoking or conditions such as pre-eclampsia - may cause problems with fertility later in life, a study carried out in rats suggests.

29 Mar 2019

Physical activity more critical to maintain weight loss than diet, study reveals

A new study from the University of Colorado Anschutz Health and Wellness Center (AHWC) at the CU Anschutz Medical Campus revealed physical activity does more to maintain substantial weight loss than diet.

29 Mar 2019

Breakthrough study could lead to new treatments for sickle cell disease

In a breakthrough study of sickle cell disease, biomedical engineers in the University of Minnesota College of Science and Engineering have revealed that the building blocks of the disease are much less efficient at organizing than previously thought.

29 Mar 2019

Fetal exposure to nicotine linked with SIDS and cardiac arrhythmias in newborns

Fetal exposure to tobacco smoke in utero is associated with sudden infant death syndrome (SIDS) and cardiac arrhythmias in newborns. In a novel study in rabbits, investigators provide the first evidence linking fetal exposure to nicotine to long-term alterations of the cardiac sodium current.

29 Mar 2019

Oxygen News and Research

Researchers uncover cellular resistance mechanisms to BRAF inhibitors in melanoma

Duration of thrombectomies proves crucial in success of the procedure

Hospital ICU patients with non-brain-related injuries may have undetected cognitive deficits

New technique uses UV and red light to decontaminate organs before transplantation

The two-hit model can lead to better understanding of heart failure

Stimulating parvalbumin-containing cells causes surprising changes in blood volume, flow

Testing how well wastewater disinfection methods affect antibiotic resistance genes

Biologists analyze available methods of targeted drug delivery to malignant tumors

Cellular protein could take on role of restriction factor for hepatitis B virus

Scientists solve mystery of how bacterial nanowires conduct electricity

Developing imaging techniques for early detection of eye and brain diseases

Researchers use metal-free catalyst to synthesize ketone from aldehyde

Finding homeless patients a place to heal

Researchers explore better treatments for irritated tendons

Photoacoustic microscopy helps scientists to better scrutinize cancer cells

Study reveals new strategy to combat antibiotic resistance

Maternal smoking and pre-eclampsia may affect fertility of offspring

Physical activity more critical to maintain weight loss than diet, study reveals

Breakthrough study could lead to new treatments for sickle cell disease

Fetal exposure to nicotine linked with SIDS and cardiac arrhythmias in newborns

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