Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

New genetic marker linked to higher risk of premenopausal breast cancer

University of Alberta researchers have added a new genetic marker to the breast cancer map, helping to expand the list of genetic mutations clinicians can watch for in cancer screenings.

20 Jun 2019

Scientists identify early signs of Parkinson’s disease years before symptoms develop

Scientists have identified the earliest signs of Parkinson’s disease in the brain up to 20 years before patients present with any symptoms.

20 Jun 2019

New blood test offers more precise diagnostics of ovarian cancer

The majority of women who undergo surgery for suspected ovarian cancer do not have cancer. A novel blood test developed by researchers at Uppsala University and the Sahlgrenska Academy, University of Gothenburg, in Sweden, now offers the possibility of more precise diagnostics without the need for surgery.

20 Jun 2019

Investigational drug for treatment of sickle cell disease shows early promise in clinical trials

An investigational drug for the treatment of sickle cell disease is showing early promise in clinical trials for impacting biomarkers of the disease in patients, reported UConn School of Medicine researchers at the European Hematology Association Congress in Amsterdam this week.

20 Jun 2019

Healthy blood vessels could help stave off cognitive decline

High blood pressure may affect conditions such as Alzheimer’s disease by interfering with the brain’s waste management system, according to new research in rats published in JNeurosci. Maintaining blood vessel health could therefore help stave off cognitive decline.

From Society for Neuroscience 19 Jun 2019

Sleep patterns can predict Alzheimer’s pathology later in life

Sleep patterns can predict the accumulation of Alzheimer’s pathology proteins later in life, according to a new study of older men and women published in JNeurosci. These findings could lead to new sleep-based early diagnosis and prevention measures in the treatment of Alzheimer’s disease.

From Society for Neuroscience 19 Jun 2019

Scientists develop new class of drugs to treat hereditary kidney disease

Scientists from the University of Sheffield are part of an international collaboration to develop a new class of drugs to treat a common genetic kidney disease which is a major cause of kidney failure.

18 Jun 2019

Novel lung map reveals new cells responsible for asthma

Researchers working on the Human Cell Atlas initiative have produced a detailed map of the human lungs that could lead to new treatments for asthma.

18 Jun 2019

Up to 80% of metastatic colorectal cancers spread to far areas before diagnoses

Up to 80% of metastatic colorectal cancers are likely to have spread to distant locations in the body before the original tumor has exceeded the size of a poppy seed, according to a study of nearly 3,000 patients by researchers at the Stanford University School of Medicine.

18 Jun 2019

Use of molecular biomarkers shows promise in early detection of endometrial cancer

The use of molecular biomarkers in minimally invasive sampling opens a promising perspective for the early detection of endometrial cancer.

18 Jun 2019

Scientists identify two genes that may play a role in prostate enlargement

For aging men, prostate enlargement is almost as common as graying hair, and yet scientists know very little about why the prostate increases in size or how the process occurs on a molecular level.

17 Jun 2019

Researchers develop new 3D tissue imaging technique to study disease at cellular level

To diagnose and treat diseases like cancer, scientists and doctors must understand how cells respond to different medical conditions and treatments.

14 Jun 2019

Experimental antiviral drug cures mice infected with deadly tick-borne virus

Only a few cases of the newly discovered Bourbon virus have been reported, and two of them ended in death, partly because no specific treatments are available for the tick-borne illness.

14 Jun 2019

First clinical test could enable personalized prognosis for triple-negative breast cancer patients

A personalized prognosis for patients diagnosed with triple-negative breast cancer was the goal of a new study by Katherine Varley, PhD, researcher at Huntsman Cancer Institute and assistant professor of oncological sciences at the University of Utah.

13 Jun 2019

New 'virtual biopsy' device developed to detect skin tumors

Using sound vibrations and pulses of near-infrared light, a Rutgers University scientist has developed a new "virtual biopsy" device that can quickly determine a skin lesion's depth and potential malignancy without using a scalpel.

13 Jun 2019

Apolipoproten E appears to be new potential druggable target for Alzheimer's

Apolipoproten E is a major genetic risk factor for the development of Alzheimer's disease, yet the protein tends to be understudied as a potential druggable target for the mind-robbing neurodegenerative disease.

13 Jun 2019

UCLA physicians find more effective method for detecting prostate cancer

Each year, 1 million men in the U.S. undergo biopsies to determine whether they have prostate cancer. The biopsy procedure traditionally has been guided by ultrasound imaging, but this method cannot clearly display the location of tumors in the prostate gland.

12 Jun 2019

Biomarker correlates with prostate cancer aggressiveness and predicts metastasis to bone

Mortality due to prostate cancer is usually related to its likelihood to metastasize, especially to bone. Prognostic biomarkers are urgently needed to predict disease aggression so that appropriate treatment can be selected.

12 Jun 2019

Singapore researchers find that a third of eczema apps do not comply with international guidelines

A third (34 per cent) of eczema management mobile applications provide information that does not agree with international treatment and condition guidelines, a study led by Nanyang Technological University, Singapore has found.

11 Jun 2019

AI technique helps produce high quality CT images at lower dosages

A team of bioengineers at Rensselaer Polytechnic Institute, with funding from the National Institute of Biomedical Imaging and Bioengineering, have developed an artificial intelligence technique that uses image post-processing to rapidly convert low-dose computed tomography scans to images of superior quality, compared to low-dose scans that do not use the AI technique.

11 Jun 2019