Aging News and Research

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Physical activity inhibits the production of insulin

When a fruit fly starts walking or flying, its insulin-producing cells are immediately inhibited. This could be one explanation for why exercise promotes health.

4 Jan 2023

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Numerous studies have shown health benefits of time-restricted eating including increase in life span in laboratory studies, making practices like intermittent fasting a hot topic in the wellness industry.

3 Jan 2023

Salk scientists show how a microprotein can increase appetite in mice

Obesity and metabolic diseases, such as diabetes, are extremely common in the United States. Tiny proteins called microproteins have long been overlooked in research, but new evidence demonstrates that they have an important role in metabolism.

3 Jan 2023

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 24, entitled, "Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers."

3 Jan 2023

Keeping hydrated can reduce aging and extend disease-free life

In a recent study published in the journal eBioMedicine, researchers assessed the association between hydration and aging.

3 Jan 2023

Weighing risks of a major surgery: 7 questions older Americans should ask their surgeon

Larry McMahon, who turns 80 this month, is weighing whether to undergo a major surgery. Over the past five years, his back pain has intensified. Physical therapy, muscle relaxants, and injections aren't offering relief.

3 Jan 2023

Insulin-like peptide 3 may be a predictor of hypogonadism and age-associated morbidity in older males

Researchers evaluated whether insulin-like peptide 3 (INSL3) could predict hypogonadism and age-associated morbidity in older males.

3 Jan 2023

Researchers use engineered proteins to record histories of cellular events

As cells perform their everyday functions, they turn on a variety of genes and cellular pathways. MIT engineers have now coaxed cells to inscribe the history of these events in a long protein chain that can be imaged using a light microscope.

2 Jan 2023

Good hydration may slow down aging and prolong disease-free life

Adults who stay well-hydrated appear to be healthier, develop fewer chronic conditions, such as heart and lung disease, and live longer than those who may not get sufficient fluids, according to a National Institutes of Health study published in eBioMedicine.

2 Jan 2023

Novel experimental approach slows physical decline and extends the lives of roundworms

Scientists in aging research today report a novel experimental approach that slowed the rate of physical decline and lengthened the lives of roundworms commonly used in biological studies, C. elgans.

30 Dec 2022

DNAm measures of biological aging linked with neuropsychologically-validated cognitive decline in midlife

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 23, entitled, "DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife."

30 Dec 2022

Unraveling the biology of senescent cells and healthy aging

Multiple researchers at the Jackson Laboratory are taking part in an ambitious research program spanning several top research institutions to study senescent cells.

29 Dec 2022

New test detects biomarker of Alzheimer's disease neurodegeneration in blood samples

A group of neuroscientists led by a University of Pittsburgh School of Medicine researcher developed a test to detect a novel marker of Alzheimer's disease neurodegeneration in a blood sample. A study on their results was published today in Brain.

28 Dec 2022

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Insilico Medicine ("Insilico"), a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced that the company's drug discovery team has nominated a preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy utilizing its end-to-end Pharma.AI platform.

27 Dec 2022

Researchers discover a protein linked with the onset of anthracycline-associated cardiac toxicity

Anthracyclines are a class of chemotherapies effective in treating many forms of cancer, including leukemias, lymphomas and breast cancer.

27 Dec 2022

PTSD, TBI, and a genetic variant show strong links with Alzheimer's Disease and related dementias

The medical community has never researched the simultaneous impact of post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), and genetic risk factors in a large cohort … until now.

22 Dec 2022

3D neutron tomography reveals water diffusion across the bone material

What keeps bones able to remodel themselves and stay healthy? A team from Charité Berlin has discovered clues to the key function of non-collagen protein compounds and how they help bone cells react to external load.

22 Dec 2022

Centene, under siege in America, moved into Britain’s National Health Service

In the final days of 2020, the U.S. health insurer Centene made a swift incursion into Britain's prized National Health Service, one of the world's largest employers.

22 Dec 2022

New methods can advance the development of rapid diagnostics for many infectious diseases

Two companion studies report new artificial intelligence approaches for identification of molecular "fingerprints" for specific infections. The methods, used here to derive a fingerprint for COVID-19, can advance the development of rapid diagnostics for many infectious diseases.

21 Dec 2022

Study reveals why human lymph nodes lose their function with age

A new study from researchers at Uppsala University presents novel findings on why human lymph nodes lose their function with age and the consequences for the effectiveness of our immune system. The article has been published in The Journal of Pathology.

21 Dec 2022

Aging News and Research

Physical activity inhibits the production of insulin

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Salk scientists show how a microprotein can increase appetite in mice

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

Keeping hydrated can reduce aging and extend disease-free life

Weighing risks of a major surgery: 7 questions older Americans should ask their surgeon

Insulin-like peptide 3 may be a predictor of hypogonadism and age-associated morbidity in older males

Researchers use engineered proteins to record histories of cellular events

Good hydration may slow down aging and prolong disease-free life

Novel experimental approach slows physical decline and extends the lives of roundworms

DNAm measures of biological aging linked with neuropsychologically-validated cognitive decline in midlife

Unraveling the biology of senescent cells and healthy aging

New test detects biomarker of Alzheimer's disease neurodegeneration in blood samples

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Researchers discover a protein linked with the onset of anthracycline-associated cardiac toxicity

PTSD, TBI, and a genetic variant show strong links with Alzheimer's Disease and related dementias

3D neutron tomography reveals water diffusion across the bone material

Centene, under siege in America, moved into Britain’s National Health Service

New methods can advance the development of rapid diagnostics for many infectious diseases

Study reveals why human lymph nodes lose their function with age

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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