Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Researchers reverse Alzheimer's symptoms in flies by restoring epigenetic balance

Researchers from Drexel University reversed symptoms of Alzheimer's disease in fruit flies by restoring the balance between two epigenetic enzymes that regulate gene expression, a study shows.

15 May 2018

NIH researchers develop new tool to better understand brain disorders

A new tool developed by researchers at the National Institutes of Health has determined, for the first time, how two distinct sets of neurons in the mouse brain work together to control movement.

14 May 2018

Gene variant may be linked to worse psychiatric symptoms in TBI patients

A variant of the APOE gene may be linked to worse psychiatric symptoms in people who have had a traumatic brain injury, found a Veterans Affairs San Diego Healthcare System study. Study participants with both the gene variant and at least one TBI had more severe symptoms of PTSD, anxiety, and depression than comparison participants.

14 May 2018

Scientists uncover genome variation linked to increased risk of developing Alzheimer's

An article published in Nature Medicine with the collaboration of the research group of Dr. Manel Esteller, director of the Epigenetics and Cancer Biology Program of the Bellvitge Biomedical Research Institute, ICREA Researcher and Professor of Genetics of the University of Barcelona, and Drs. Dave Monk and Isidre Ferrer, from the same center, shows that the inheritance of small changes in DNA alters the expression of the PM20D1 gene and is associated with an increased risk of developing Alzheimer's disease.

14 May 2018

New study to explore link between diet, intestinal microbiota and cognitive decline

Are abnormal intestinal microorganisms a risk factor for developing cognitive impairment? Researchers at Rush University Medical Center are trying to answer that question with a new study that will explore how the intestinal microbiota – the bacteria in the intestine –influence the progression of cognitive decline and the development of Alzheimer's disease.

14 May 2018

New model based on combination of GANs with reinforcement learning for drug discovery

Insilico Medicine, a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for target identification, drug discovery and aging research announces the publication of a new research paper in Molecular Pharmaceutics journal titled "Adversarial Threshold Neural Computer for Molecular De Novo Design".

10 May 2018

New Facebook app provides much-needed support to unpaid caregivers of Alzheimer's patients

Researchers at IUPUI have developed a Facebook app that, a study shows, offers a way to provide much-needed support to unpaid caregivers of people with Alzheimer's disease.

10 May 2018

Researchers devise neuronal cookbook for turning skin cells into different types of neurons

Scientists at The Scripps Research Institute have devised what they call a "neuronal cookbook" for turning skin cells into different types of neurons.

10 May 2018

Study: Different strains of same protein may contribute to different Parkinson's-related brain disorders

Different Parkinson's-related brain disorders, called synucleionpathies, are characterized by misfolded proteins embedded in cells.

10 May 2018

Researchers find link between depression and memory problems, brain aging

Depression in older adults may be linked to memory problems, according to a study published in the May 9, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology.

9 May 2018

Johns Hopkins researchers identify protein clumps in diseased hearts

Similar to how protein clumps build up in the brain in people with some neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, protein clumps appear to accumulate in the diseased hearts of mice and people with heart failure, according to a team led by Johns Hopkins University researchers.

9 May 2018

Scientists use X-ray laser to gain insights into structure of Alzheimer's proteins

A new experimental method permits the X-ray analysis of amyloids, a class of large, filamentous biomolecules which are an important hallmark of diseases such as Alzheimer's and Parkinson's.

9 May 2018

Study adds robust evidence to higher prevalence of Alzheimer's among women than men

The APOE gene, the strongest genetic risk factor for Alzheimer's disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer's Center.

8 May 2018

Scientists successfully test anti-alcoholism drug in animal models

Scientists at The University of Texas at Austin have successfully tested in animals a drug that, they say, may one day help block the withdrawal symptoms and cravings that incessantly coax people with alcoholism to drink.

4 May 2018

Astrocyte-targeted treatment may help alleviate symptoms of Alzheimer’s disease

A study by scientists of the German Center for Neurodegenerative Diseases points to a novel potential approach against Alzheimer's disease.

4 May 2018

Frequent saunas may have beneficial effects on vascular health

Taking frequent saunas may be linked to a lower risk of stroke, according to a study published in the May 2, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology.

3 May 2018

UCLA researchers report promising drug strategy to block tau transmission

Alzheimer's disease destroys brain cells in part by promoting the formation of insoluble clumps that contain a protein called tau.

3 May 2018

Study opens the way for potential new dementia treatments with existing drugs

A new research study by scientists in Australia and the US provides an explanation for why clinical trials of drugs reducing proteins in the brain that were thought to cause dementia and Alzheimer's have failed. The study has opened the way for potential new treatments with existing drugs.

2 May 2018

Research team uncovers link between circadian clock and aggression center in the brain

Each year around many people worldwide are diagnosed with a form of dementia. Alzheimer's disease is one of them. The disease manifests itself in memory difficulties in particular, but can also result in personality changes and mood swings.

2 May 2018

Potential new treatments for dementia and Alzheimer’s Disease

A study published has uncovered why clinical drug trials reducing proteins associated with the onset of Alzheimer’s Disease and dementia have been unsuccessful.

2 May 2018

Alzheimer's Disease News and Research

Further Reading

Researchers reverse Alzheimer's symptoms in flies by restoring epigenetic balance

NIH researchers develop new tool to better understand brain disorders

Gene variant may be linked to worse psychiatric symptoms in TBI patients

Scientists uncover genome variation linked to increased risk of developing Alzheimer's

New study to explore link between diet, intestinal microbiota and cognitive decline

New model based on combination of GANs with reinforcement learning for drug discovery

New Facebook app provides much-needed support to unpaid caregivers of Alzheimer's patients

Researchers devise neuronal cookbook for turning skin cells into different types of neurons

Study: Different strains of same protein may contribute to different Parkinson's-related brain disorders

Researchers find link between depression and memory problems, brain aging

Johns Hopkins researchers identify protein clumps in diseased hearts

Scientists use X-ray laser to gain insights into structure of Alzheimer's proteins

Study adds robust evidence to higher prevalence of Alzheimer's among women than men

Scientists successfully test anti-alcoholism drug in animal models

Astrocyte-targeted treatment may help alleviate symptoms of Alzheimer’s disease

Frequent saunas may have beneficial effects on vascular health

UCLA researchers report promising drug strategy to block tau transmission

Study opens the way for potential new dementia treatments with existing drugs

Research team uncovers link between circadian clock and aggression center in the brain

Potential new treatments for dementia and Alzheimer’s Disease

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