Tumor News and Research

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Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Immune checkpoint inhibitors (ICIs) are widely sought after for the treatment of different types of cancers. Unfortunately, only 20–30% patients with cancer respond to ICI treatment.

29 Mar 2023

Synthetic hydrogel-based lymphoma tumor model paves way for personalized cancer therapies

In recent years, innovative cancer drugs that target specific molecular drivers of the disease have been embraced as the treatment of choice for many types of cancer.

29 Mar 2023

Mouse avatars could help design more effective and personalized therapies for multiple myeloma

An international group of researchers, led by Dr. José Ángel Martínez-Climent at the Cima University of Navarra, has created mouse avatars of patients with multiple myeloma to study and develop personalized treatments against this blood cancer, the second most frequent hematological cancer and incurable in most cases.

29 Mar 2023

Drugs to activate STING could help prevent cancer metastasis

A team of scientists at the Sloan Kettering Institute have identified the STING cellular signaling pathway as a key player in keeping dormant cancer cells from progressing into aggressive tumors months, or even years, after they've escaped from a primary tumor.

29 Mar 2023

Advanced pancreatic cancer model more accurately depicts PDAC tumor progression

Pancreatic ductal adenocarcinoma (PDAC), is highly aggressive and lethal. It is the most prevalent type of pancreatic cancer, making up 90% of cases; it also has a high rate of metastasis, with an average five-year survival rate of less than 10%.

29 Mar 2023

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

Researchers compared the effects of consuming red-fleshed apples and white-fleshed among healthy adults.

29 Mar 2023

Clockwork in cancer: the importance of the circadian rhythm in the formation and progression of tumors

Researchers reviewed the importance of the circadian rhythm in the formation and progression of tumors.

29 Mar 2023

How do viral infections cause autoimmune diseases?

Researchers describe the pathological mechanisms of virus-induced autoimmune diseases.

28 Mar 2023

Capsaicin and its health benefits

Researchers examine the health benefits associated with capsaicin, with a particular focus on how this compound impacts cognition and cardiovascular health.

28 Mar 2023

3D cell culture system tests how inhibiting fibroblast activities can help treat lung cancer

Fibroblasts build and maintain the extracellular matrix, or physical scaffolding for cells, in the connective tissues within the body.

28 Mar 2023

Chemotherapy plus immunotherapy improves outcomes in patients with advanced endometrial cancer

Endometrial cancer, which makes up about 90% of uterine cancers, will be diagnosed in more than 65,000 people in the United States this year.

28 Mar 2023

Notorious oncogene plays a direct role in disguising growing cancers from the immune system

Cancer-associated genes called oncogenes are well known to stimulate cell growth and division — causing tumors to balloon and spread.

28 Mar 2023

Newly found strategy used by metastasized tumors may explain why some promising immunotherapies fail

Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.

28 Mar 2023

Using a selective dye to label macrophages associated with cancer progression

M1 and M2 are activated macrophages that protect our immune system and maintain homeostasis.

28 Mar 2023

CD9-positive exosomes inhibit the growth of malignant melanoma, study suggests

Malignant melanoma is a relatively aggressive type of skin cancer. When detected early, it is usually treatable by surgical resection only, but metastases develop often spreading to distant areas.

28 Mar 2023

Pneumolysin toxin holds promise for developing therapies against Streptococcus pneumoniae

In a recent study published in the journal PLoS ONE, researchers in Spain performed a systematic review of pneumolysin (PLY) toxin as a molecular target to develop novel therapeutics against Streptococcus pneumoniae.

27 Mar 2023

Breast tumors of women from different racial groups have diverse cellular, microbial and genomic features

The breast tumors of Asian, Black and white women have very different cellular, microbial and genomic features that could potentially be used to personalize care or predict disease progression, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center.

27 Mar 2023

Targeting the STING pathway with a combination strategy promotes antitumor activity

Immunotherapies have greatly improved the outcomes of many patients with melanoma. But there is still a need for new approaches for the subset of patients who do not respond well to this type of therapy.

27 Mar 2023

Enhancing the effectiveness of immunization against certain cancers

In addition to an antigen, many vaccines also contain substances, called adjuvants, which stimulate the immune system.

27 Mar 2023

Ask the Expert: 7 Questions about Colorectal Cancer & Non-invasive Fecal DNA Testing

In this interview, NewsMedical speaks with Dr. Yuying Wang, R&D Director (Oncology), from BGI Genomics, about colorectal cancer and the development and application of COLOTECT® 1.0, a non-invasive fecal DNA test for the detection of colorectal cancer and pre-cancerous lesions.

From BGI Genomics 27 Mar 2023

Tumor News and Research

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Synthetic hydrogel-based lymphoma tumor model paves way for personalized cancer therapies

Mouse avatars could help design more effective and personalized therapies for multiple myeloma

Drugs to activate STING could help prevent cancer metastasis

Advanced pancreatic cancer model more accurately depicts PDAC tumor progression

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

Clockwork in cancer: the importance of the circadian rhythm in the formation and progression of tumors

How do viral infections cause autoimmune diseases?

Capsaicin and its health benefits

3D cell culture system tests how inhibiting fibroblast activities can help treat lung cancer

Chemotherapy plus immunotherapy improves outcomes in patients with advanced endometrial cancer

Notorious oncogene plays a direct role in disguising growing cancers from the immune system

Newly found strategy used by metastasized tumors may explain why some promising immunotherapies fail

Using a selective dye to label macrophages associated with cancer progression

CD9-positive exosomes inhibit the growth of malignant melanoma, study suggests

Pneumolysin toxin holds promise for developing therapies against Streptococcus pneumoniae

Breast tumors of women from different racial groups have diverse cellular, microbial and genomic features

Targeting the STING pathway with a combination strategy promotes antitumor activity

Enhancing the effectiveness of immunization against certain cancers

Ask the Expert: 7 Questions about Colorectal Cancer & Non-invasive Fecal DNA Testing

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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