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Modeling emergence and dynamics of new COVID-19 variants in the UK

Computer simulations describe global features observed in the daily number of cases and can be applied to any country of interest.

3 Dec 2021

Study documents and visualizes hearing loss-associated genes in the inner ear

Researchers from Uppsala University have been able to document and visualise hearing loss-associated genes in the human inner ear, in a unique collaboration study between otosurgeons and geneticists.

2 Dec 2021

SARS-CoV-2 evolution in animals could provide insights on the mutability of COVID-19

When animals catch COVID-19 from humans, new SARS-CoV-2 variants can arise. To evaluate this phenomenon, an interdisciplinary team at the College of Veterinary Medicine and Biomedical Sciences systematically analyzed mutation types occurring in the virus after infection of cats, dogs, ferrets, and hamsters.

2 Dec 2021

Men with inherited gene mutation have high risk of aggressive prostate cancer

Men who inherit mutations in a gene called TP53 have a high risk of developing aggressive prostate cancer, a multicenter research team in the United States has found.

2 Dec 2021

Researchers introduce new method for observing cell interactions

Researchers created a system that allows scientists to ‘log’ a cell’s reactions to external stimuli within the cell’s genetic material.

2 Dec 2021

New bioinformatics method for viral sgRNA analysis

A recent study discusses a bioinformatics method to help identify and explore sgRNAs uncovered in next-generation sequencing data.

2 Dec 2021

Large study of plasma proteome unravels its genetic determinants and relationship with human disease

In a study published today in Nature Genetics, scientists at deCODE genetics , a subsidiary of the pharmaceutical company Amgen, demonstrate how measuring the levels of a large number of proteins in plasma at population scale when combined with data on sequence diversity and RNA expression dramatically increases insights into human diseases and other phenotypes.

2 Dec 2021

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

A new study has focussed on assessing the Mpro mutants of newly emerged SARS-CoV-2 variants.

2 Dec 2021

Novel approach to estimate transmission advantage of SARS-CoV-2 variants in real-time

A new study retrospectively estimates the effective transmission advantage of the Alpha variant as compared to other non-VOC lineages.

1 Dec 2021

Plant-derived virus-like particle vaccines against SARS-CoV-2

In a review published in Biotechnology Letters, the authors discuss plant-derived VLP-based vaccines.

1 Dec 2021

Novel nanopore technique for annotation of SARS-CoV-2 capping sites and understanding sgRNA structure

New research examined SARS-CoV-2 transcripts in order to understand how it expresses its gene products in the infected host.

1 Dec 2021

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

With the world still in the grip of a devastating pandemic, it's hard to imagine viruses as something other than hostile enemies to be vanquished.

30 Nov 2021

Scientists identify a new therapeutic target for HIV

Scientists in Montreal and London have identified the key role played by transcription factorRORC2 in HIV infection: the molecule attaches itself to parts of the virus's genome yet doesn't prevent it from replicating.

30 Nov 2021

Host and in vitro genomic variability of SARS-CoV-2 and its variants

Researchers from the University of Sydney investigate the genomic variability of SARS-CoV-2 within the host and in vitro.

30 Nov 2021

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

A new paper deals with the identification of an antiviral compound that could help in developing additional drugs to help fight COVID-19.

30 Nov 2021

Researchers dissect the shared genetic architecture of suicide attempts and psychiatric disorders

In the largest genetic study of suicide attempts to date, researchers have identified a region of the genome on chromosome 7 containing DNA variations that increase the risk that a person will attempt suicide.

30 Nov 2021

Targeted measures to prevent the spread of Omicron variant take effect from 30 November 2021

Targeted measures to prevent the spread of the new COVID-19 Omicron variant take effect from 4am today [Tuesday 30 November].

29 Nov 2021

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Researchers study human single nucleotide variants (SNVs) using machine learning to identify amino acid changes that alter kinase-bound sequence motifs.

29 Nov 2021

An update of what is currently known about Omicron

On 26 November 2021, WHO designated the variant B.1.1.529 a variant of concern, named Omicron, on the advice of WHO's Technical Advisory Group on Virus Evolution (TAG-VE).

29 Nov 2021

UC San Diego's Scott Lippman to launch and lead NCI-sponsored PreCancer Genome Atlas

Scott Lippman, MD, will launch and lead the PreCancer Genome Atlas, a National Cancer Institute (NCI)-sponsored effort to map in time and space all of the molecular, cellular and structural characteristics of premalignant lesions and how they evolve into invasive cancers.

29 Nov 2021

Genome News and Research

Modeling emergence and dynamics of new COVID-19 variants in the UK

Study documents and visualizes hearing loss-associated genes in the inner ear

SARS-CoV-2 evolution in animals could provide insights on the mutability of COVID-19

Men with inherited gene mutation have high risk of aggressive prostate cancer

Researchers introduce new method for observing cell interactions

New bioinformatics method for viral sgRNA analysis

Large study of plasma proteome unravels its genetic determinants and relationship with human disease

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

Novel approach to estimate transmission advantage of SARS-CoV-2 variants in real-time

Plant-derived virus-like particle vaccines against SARS-CoV-2

Novel nanopore technique for annotation of SARS-CoV-2 capping sites and understanding sgRNA structure

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

Scientists identify a new therapeutic target for HIV

Host and in vitro genomic variability of SARS-CoV-2 and its variants

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

Researchers dissect the shared genetic architecture of suicide attempts and psychiatric disorders

Targeted measures to prevent the spread of Omicron variant take effect from 30 November 2021

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

An update of what is currently known about Omicron

UC San Diego's Scott Lippman to launch and lead NCI-sponsored PreCancer Genome Atlas

Genetics & Genomics - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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