Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

New liquid biopsy detects early cancers through epigenetic instability

Researchers at the Johns Hopkins Kimmel Cancer Center have developed a novel liquid biopsy approach to identify early-stage cancers by measuring the random variation in DNA methylation patterns, rather than the absolute level of those patterns as in other liquid biopsies.

2 Feb 2026

King’s researchers help transform UK mental health research infrastructure

King’s researchers will help transform mental health data, clinical trials and industry partnerships as part of the UK Government’s Mental Health Goals programme.

30 Jan 2026

Researchers develop blood test to find pancreatic ductal adenocarcinoma

National Institutes of Health (NIH)-supported investigators have developed a blood test to find pancreatic ductal adenocarcinoma, one of the deadliest forms of cancer.

30 Jan 2026

Research uncovers why certain brain cells are more resilient to tau protein buildup

New research by UCLA Health and UC San Francisco has uncovered why certain brain cells are more resilient than others to the buildup of a toxic protein that is a hallmark of Alzheimer's disease and related dementias, potentially leading to new targets for therapies or treatments.

30 Jan 2026

Aptamer-based wearables revolutionize continuous health tracking

Continuous monitoring of biomarkers is essential for early disease detection, treatment evaluation, and personalized health management, yet most clinical tests rely on invasive, single-point blood sampling. Recent advances in aptamer-based wearable electrochemical sensors offer a promising alternative by enabling real-time, continuous tracking of physiological signals directly in or on the body.

30 Jan 2026

Neighborhood disadvantage accelerates biological aging through emotional distress

While scientists have long known that living in a disadvantaged neighborhood is associated with biological symptoms of accelerated aging, emotional distress accounts for a significant portion of these effects, researchers found in a recent study.

29 Jan 2026

Soluble E-cadherin drives brain metastasis in aggressive inflammatory breast cancer

Researchers at The University of Texas MD Anderson Cancer Center have identified a targetable driver of brain metastases in patients with aggressive inflammatory breast cancer.

28 Jan 2026

Four-biomarker blood panel enhances the detection of pancreatic ductal adenocarcinoma

A four-biomarker blood panel of aminopeptidase N (ANPEP), polymeric immunoglobulin receptor (PIGR), CA19-9, and thrombospondin-2 (THBS2) enhanced the detection of pancreatic ductal adenocarcinoma (PDAC) compared to measuring CA19-9 levels alone.

28 Jan 2026

Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy

Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why some cancer patients benefit from immunotherapy while others do not.

27 Jan 2026

Vortex Biotech opens new state-of-the-art laboratory at Manchester Science Park

Vortex Biotech Holdings Limited has announced the opening of its advanced laboratory facilities at Manchester Science Park.

27 Jan 2026

Multi-fluid microRNA signals as markers of endometriosis

Researchers uncover distinct microRNA profiles in bodily fluids, offering insights into noninvasive diagnostic markers for endometriosis and its complexities.

27 Jan 2026

Blood protein albumin identified as key defense against deadly black fungus

A new international study published in Nature has identified albumin, the most abundant protein in human blood, as a powerful and previously unrecognized defense against mucormycosis, a rare but often fatal fungal infection.

27 Jan 2026

Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, particularly in regions with high hepatitis B virus prevalence.

24 Jan 2026

New assessment framework improves evaluation of cutaneous chronic graft-versus-host disease

An international task force of medical experts recently proposed major revisions to the way doctors measure treatment success for a common–and often severe–skin complication of stem cell transplantation.

24 Jan 2026

Blood-based epigenetic signatures enable early risk assessment in prediabetes

Prediabetes is an extremely heterogeneous metabolic disorder. Scientists from several partner institutes of the German Center for Diabetes Research (DZD) have now used artificial intelligence (AI) to identify epigenetic markers that indicate an elevated risk of complications.

24 Jan 2026

Cigarette compound exposure drives sorafenib resistance in hepatocellular carcinoma

A research team led by Professor Yuan Li at Nanjing Medical University published a research paper entitled "A Cigarette Compound-Induced Tumor Microenvironment Promotes Sorafenib Resistance in Hepatocellular Carcinoma via the 14-3-3η-Modified Tumor-Associated Proteome" in the Chinese Medical Journal.

23 Jan 2026