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Insights into antibiotic resistance and virulence of Bordetella hinzii

Announcing a new article publication for Zoonoses journal. This study was aimed at analyzing the pathogenic characteristics of Bordetella hinzii (B. hinzii), and elucidating its antibiotic resistance mechanisms, virulence gene distribution, and vaccine development potential.

23 Jul 2025

Deep-sea bacterial compound triggers pyroptosis to fight cancer

Promoting pyroptosis-an inflammatory form of programmed cell death-has become a promising treatment strategy for cancer.

23 Jul 2025

Probiotic bacteria found to reshape cell behavior in vitro

This study reveals how probiotic bacteria directly influence brain cell function, highlighting gut-brain communication and potential therapeutic applications.

23 Jul 2025

Blocking a single gene disrupts vitamin D metabolism and cancer pathways in new cell study

Researchers identified SDR42E1 as a key regulator of vitamin D absorption and sterol metabolism in colorectal cancer cells. Disruption of this enzyme altered cancer-related pathways and cell viability, highlighting its potential as a therapeutic target.

21 Jul 2025

Muscle-derived vesicles heal damaged cells and reverse disease in new study

Researchers discovered that mitochondria-rich extracellular vesicles (Ti-mitoEVs) from skeletal muscle can deliver healthy mitochondria to damaged cells, restoring energy and promoting tissue repair in mice. The approach reversed acute muscle injury and chronic kidney disease, offering a promising new regenerative therapy.

21 Jul 2025

Novel polysaccharide from Albizzia julibrissin shows promise against pancreatic cancer

Albizzia julibrissin is a widely distributed plant in China. Its dried stem bark has been used in traditional oriental medicine to treat insomnia, diuresis, sthenia, ascaricide, and confusion.

21 Jul 2025

AI reshapes ARDS care by predicting risk, guiding ventilation, and personalizing treatment

Artificial intelligence and machine learning are transforming acute respiratory distress syndrome (ARDS) management, enabling earlier detection, precision risk stratification, and tailored therapies. Emerging AI techniques promise to improve outcomes, but real-world clinical validation and integration remain critical challenges.

21 Jul 2025

AI turns old diabetes drug Halicin into a potent weapon against superbugs

Researchers found that Halicin, an AI-identified drug, effectively inhibited most multidrug-resistant bacteria except Pseudomonas aeruginosa. The study highlights Halicin’s broad-spectrum antibacterial potential and the transformative role of artificial intelligence in antibiotic discovery.

20 Jul 2025

Lipoxygenase emerges as a promising antiviral agent against severe fever with thrombocytopenia syndrome

Severe fever with thrombocytopenia syndrome (SFTS) was reported in Asia, with a fatality rate that can reach as high as 50%.

18 Jul 2025

From chemistry to life: Building synthetic cells with metabolism

At some point during the evolution of life on Earth, inorganic matter became organic, nonliving matter became living. How this happened is one of humankind's greatest mysteries.

17 Jul 2025

How can super-resolution technology help study neurotransmission?

Discover how super-resolution technology can be used to sudy neurotransmission at inhibitory synapses.

From Bruker Nano Surfaces and Metrology 17 Jul 2025

Mapping the metabolic journey of blood stem cells

Researchers from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and ETH Zürich have created the first integrated map detailing the metabolic and molecular changes in human blood stem cells as they age, specialize, or turn cancerous.

15 Jul 2025

Person-focused approach explains distinct autism genetic subtypes

Research identifies four autism classes driven by different genes, enhancing understanding of ASD's genetic complexity and improving diagnostic approaches.

15 Jul 2025

Genetic secrets of Spanish flu revealed through century-old sample

Researchers from the universities of Basel and Zurich have used a historical specimen from UZH's Medical Collection to decode the genome of the virus responsible for the 1918-1920 influenza pandemic in Switzerland.

14 Jul 2025

New nanobody-liposome combo stops lung cancer growth and delivers targeted chemotherapy

Researchers engineered a nanobody-conjugated liposome (A5-LNP-DOX) that targets CD155 and delivers doxorubicin directly to lung adenocarcinoma cells, dramatically suppressing tumor growth in preclinical models. This approach not only inhibited cancer cell migration and invasion but also showed strong potential for safer, more precise lung cancer therapy.

14 Jul 2025

Dual targeting of lipid kinases offers hope against emerging viruses

Lipid kinases are enzymes that play a critical role in both cell signalling and membrane trafficking by phosphorylating lipid molecules in the body.

14 Jul 2025

Cheese and milk in Italy show alarming levels of microplastic contamination

Researchers found microplastics in nearly all Italian supermarket milk, fresh cheese, and ripened cheese samples, with ripened cheese containing the highest levels. The study highlights how dairy processing and packaging steps increase microplastic contamination in common foods.

13 Jul 2025