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Advancements and clinical translation of intelligent nanodrugs for breast cancer treatment

A comprehensive review in "Biofunct. Mater." meticulously details the most recent advancements and clinical translation of intelligent nanodrugs for breast cancer treatment.

24 Oct 2025

New York Regional Diabetes Research Center established with $10.8 million NIH grant

Albert Einstein College of Medicine has received a five-year, $10.8 million grant from the National Institutes of Health (NIH) to create the New York Regional Diabetes Research Center (NYR-DRC), a newly expanded multi-institutional center co-led with the Icahn School of Medicine at Mount Sinai and Weill Cornell Medicine.

23 Oct 2025

New noninvasive device measures brain blood flow using laser speckle technology

Measuring blood flow in the brain is critical for responding to a range of neurological problems, including stroke, traumatic brain injury (TBI) and vascular dementia.

21 Oct 2025

Genetic inflammatory signature defines depression subtypes and treatment response

Researchers led by Prof. Alessandro Serretti at Kore University of Enna have identified a genetic inflammatory signature that defines specific depression subtypes and influences how patients respond to antidepressant medications, according to new peer-reviewed research published today in Genomic Psychiatry.

21 Oct 2025

Exercise can mitigate depression-like behaviors induced by high-fat, high-sugar diets

Researchers led by Professor Yvonne Nolan at University College Cork have identified specific metabolic pathways through which exercise counteracts the negative behavioral effects of consuming a Western-style cafeteria diet.

21 Oct 2025

Researchers discover how a brain circuit allows eating despite anxiety

How do mammals manage to eat in situations that cause anxiety, step into exposed spaces, or slow down when anxiety drives them to keep moving? A new study pinpoints a leptin-sensitive circuit in the lateral hypothalamus that helps to overcome anxiety to perform essential behaviors such as exploring, feeding, and limiting maladaptive hyperactivity.

21 Oct 2025

Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage

Chronic alcohol use accelerates Alzheimer’s disease (AD) progression by intensifying oxidative stress, neuroinflammation, and amyloid-tau pathology through shared molecular pathways. The review highlights emerging therapies, targeting TLR4, GSK-3β, and metabolic dysfunction, that may mitigate alcohol-induced neurodegeneration.

20 Oct 2025

New technology enables fast and durable 3D-printed dental crowns

University of Texas at Dallas researchers have developed a technology that enables same-day, 3D-printed dental restorations made of zirconia, the gold-standard material for permanent dental work.

16 Oct 2025

CRISPR therapy shows promise against influenza in human lung chips

The Influenza A virus (IAV) has been the cause of six major flu pandemics, responsible for 50 to 100 million deaths globally.

15 Oct 2025

New AI system connects hidden clues in medical records to transform diagnosis

Doctors often must make critical decisions in minutes, relying on incomplete information. While electronic health records contain vast amounts of patient data, much of it remains difficult to interpret quickly-especially for patients with rare diseases or unusual symptoms.

15 Oct 2025

New insights into MDMA therapy for PTSD and beyond

A comprehensive peer-reviewed invited review published today in Psychedelics by Dr. Kenji Hashimoto and colleagues (Dr. Mingming Zhao and Dr. Jianjun Yang) synthesizes the evolving landscape of MDMA-assisted psychotherapy, examining robust clinical evidence in treatment-resistant posttraumatic stress disorder while identifying promising applications in autism spectrum disorder, eating disorders, and existential distress

14 Oct 2025

Breakthrough AI method redefines how doctors analyze medical images

When doctors analyze a medical scan of an organ or area in the body, each part of the image has to be assigned an anatomical label. If the brain is under scrutiny for instance, its different parts have to be labeled as such, pixel by pixel: cerebral cortex, brain stem, cerebellum, etc.

14 Oct 2025

Western diet fuels IBD by derailing the microbiome - can precision nutrition turn the tide?

This review examines how Western dietary patterns, high in ultra-processed foods, salt, and unhealthy fats, disrupt gut microbiota, impair immune regulation, and contribute to the global rise of inflammatory bowel disease (IBD). It highlights systems biology and nutritional epidemiology as essential tools to develop personalised dietary strategies and shift IBD care from treatment to prevention.

12 Oct 2025

Multimodal nanocarriers offer targeted solutions for tumor treatment

Cancer remains a leading cause of global morbidity and mortality. Traditional therapies like chemotherapy and radiotherapy are often limited by their lack of specificity, leading to systemic toxicity and the emergence of drug resistance.

10 Oct 2025

Slow speech improves rhythm control in people with ALS

Speech rhythm, a key attribute of natural languages that directly influences the effectiveness and efficiency of communication, is often compromised in people with neurodegenerative diseases such as Amyotrophic Lateral Sclerosis, or ALS.

10 Oct 2025

Decoding the signaling networks and metabolic dysregulation underlying sepsis

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction.

10 Oct 2025

Advances in nanomaterials revolutionize therapy for myocardial ischemia-reperfusion injury

Ischemic heart disease is the leading cause of death globally, causing approximately 9 million deaths annually.

10 Oct 2025

Multimodal AI brings a new dimension to cardiovascular medicine

Although artificial intelligence has already shown promise in cardiovascular medicine, most existing tools analyze only one type of data—such as electrocardiograms or cardiac images—limiting their clinical utility.

10 Oct 2025

Nanoparticle vaccine shows promise in preventing multiple cancers in mice

A study led by University of Massachusetts Amherst researchers demonstrates that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic and triple-negative breast cancer in mice.

9 Oct 2025

The ISSCR releases new resource to accelerate the development of PSC-derived therapies

The International Society for Stem Cell Research (ISSCR) is proud to announce the release of Best Practices for the Development of Pluripotent Stem Cell-Derived Cellular Therapies, a comprehensive, interactive new resource designed to accelerate the translation of human pluripotent stem cell (PSC)-derived therapies into clinical trials and commercial use.

9 Oct 2025

Translation News and Research

Advancements and clinical translation of intelligent nanodrugs for breast cancer treatment

New York Regional Diabetes Research Center established with $10.8 million NIH grant

New noninvasive device measures brain blood flow using laser speckle technology

Genetic inflammatory signature defines depression subtypes and treatment response

Exercise can mitigate depression-like behaviors induced by high-fat, high-sugar diets

Researchers discover how a brain circuit allows eating despite anxiety

Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage

New technology enables fast and durable 3D-printed dental crowns

CRISPR therapy shows promise against influenza in human lung chips

New AI system connects hidden clues in medical records to transform diagnosis

New insights into MDMA therapy for PTSD and beyond

Breakthrough AI method redefines how doctors analyze medical images

Western diet fuels IBD by derailing the microbiome - can precision nutrition turn the tide?

Multimodal nanocarriers offer targeted solutions for tumor treatment

Slow speech improves rhythm control in people with ALS

Decoding the signaling networks and metabolic dysregulation underlying sepsis

Advances in nanomaterials revolutionize therapy for myocardial ischemia-reperfusion injury

Multimodal AI brings a new dimension to cardiovascular medicine

Nanoparticle vaccine shows promise in preventing multiple cancers in mice

The ISSCR releases new resource to accelerate the development of PSC-derived therapies

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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