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MV130 immunotherapy boosts natural and vaccine-induced SARS-CoV-2 immunity in mice

A new mouse study found that intranasal administration of MV130 protected against severe acute respiratory syndrome coronavirus 2.

13 Dec 2021

A method to eliminate mutants in the furin cleavage site of SARS-CoV-2 in Calu-3 cells

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12 Dec 2021

Autonomous genome annotation of SARS-CoV-2 genes, proteins and domains

In a new research paper, a group of scientists from various institutions offers a semi-supervised custom pipeline for annotating all SARS-CoV-2 genes, proteins, and functional domains.

12 Dec 2021

A pandemic-scale phylogenetic analysis tool

Researchers develop a phylogenetic package that incorporated several pandemic-specific optimization and parallelization techniques.

12 Dec 2021

A new rapid and inexpensive PCR method to detect SARS-CoV-2 Omicron variant

A new study reports a method using four PCR tests to distinguish infection with the Omicron variant from that caused by other variants.

12 Dec 2021

First locally acquired infection of Omicron variant confirmed in San Diego

Officials at the San Diego County Health and Human Services Agency, working in collaboration with scientists at University of California San Diego and Scripps Research, have announced the second confirmed case — and first locally acquired infection — of the Omicron variant of SARS-CoV-2, the virus that causes COVID-19.

12 Dec 2021

Novel immunotherapy shows promise for children, young adults with recurrent AML

An immunotherapy harnessing the immune system's "natural killer" cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return.

12 Dec 2021

TP53 mutations in men may predispose to aggressive prostate cancer

Men who have mutations in a gene called TP53 have a high risk of developing aggressive prostate cancer, a multicenter research team in the United States has found.

11 Dec 2021

Viruses do not lead to new antibiotic resistance, can be our allies in defeating pathogenic bacteria

Viruses may sometimes be our enemies, but they can also be our allies. When our medicines are no longer effective, viruses can be valuable partners in defeating pathogenic bacteria.

10 Dec 2021

Assessing the risk of Omicron variant transmission by travelers from South Africa

A new study led by a multinational team of researchers studied the risk of importation of the Omicron variant by travelers from South Africa.

9 Dec 2021

Evolution of the SARS-CoV-2 omicron variant

Study shows that the omicron variant shares a common ancestry with the VOI lambda and has evolved mainly because of non-synonymous mutations.

9 Dec 2021

Mass-spectrometry and PCR testing identifies various targets related to SARS-CoV-2 VOCs

New research posted to the medRxiv* preprint server suggests that the Agena MassARRAY SARS-CoV-2 Panel PCR test effectively detects a variety of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants.

9 Dec 2021

Researchers identify a molecular culprit for COVID-19's seasonal nature

Not to pile on, but winter is coming and the COVID-19 pandemic is about to get worse. Not necessarily because of omicron – scientists are still working that one out – but because there’s more evidence than ever that COVID-19 is a seasonal disease.

8 Dec 2021

AlphaFold AI predicts SARS-CoV-2 omicron variant might not evade antibody neutralization

In a new study, scientists have computationally predicted the structure of the Omicron spike RBD from available sequences and explored the dynamics of antigen-antibody interactions.

8 Dec 2021

Diverse genome sequences generate a polygenic risk score to predict heart disease risk

In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease.

8 Dec 2021

Interactions between RNA viruses and human RNA-binding proteins

During the virus's attempt to use the host cell to replicate, host proteins interact heavily with the viral genome. Researchers have been investigating these interactions.

8 Dec 2021

Equilibrium simulation of SARS-CoV-2 spike protein highlights its global conformational characteristics

A team of researchers set out to build a full-length, membrane-embedded spike to study its conformational dynamics at the atomic level using molecular dynamics simulations to understand better how this important component of the virus machinery works.

8 Dec 2021

Study analyzes the contribution of AI to cancer patient care and vaccine design

Artificial Intelligence/Machine Learning (AI/ML) is the development of computer systems that are able to perform tasks that would normally require human intelligence. AI/ML is used by people every day, for example, while using smart home devices or digital voice assistants.

8 Dec 2021

Epigenetic clocks have potential as biomarkers of COVID-19 vaccine responses

New findings have important implications for research into the impact of COVID-19 and the mRNA vaccination on epigenetic aging in the immune system.

7 Dec 2021

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

A recent review looks at the molecular design of pH-sensitive cationic lipids and their applications for various tissues and cell types.

7 Dec 2021

Genome News and Research

MV130 immunotherapy boosts natural and vaccine-induced SARS-CoV-2 immunity in mice

A method to eliminate mutants in the furin cleavage site of SARS-CoV-2 in Calu-3 cells

Autonomous genome annotation of SARS-CoV-2 genes, proteins and domains

A pandemic-scale phylogenetic analysis tool

A new rapid and inexpensive PCR method to detect SARS-CoV-2 Omicron variant

First locally acquired infection of Omicron variant confirmed in San Diego

Novel immunotherapy shows promise for children, young adults with recurrent AML

TP53 mutations in men may predispose to aggressive prostate cancer

Viruses do not lead to new antibiotic resistance, can be our allies in defeating pathogenic bacteria

Assessing the risk of Omicron variant transmission by travelers from South Africa

Evolution of the SARS-CoV-2 omicron variant

Mass-spectrometry and PCR testing identifies various targets related to SARS-CoV-2 VOCs

Researchers identify a molecular culprit for COVID-19's seasonal nature

AlphaFold AI predicts SARS-CoV-2 omicron variant might not evade antibody neutralization

Diverse genome sequences generate a polygenic risk score to predict heart disease risk

Interactions between RNA viruses and human RNA-binding proteins

Equilibrium simulation of SARS-CoV-2 spike protein highlights its global conformational characteristics

Study analyzes the contribution of AI to cancer patient care and vaccine design

Epigenetic clocks have potential as biomarkers of COVID-19 vaccine responses

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

Genetics & Genomics - Second Edition eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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