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Genomic sequences from all over the world help fight SARS-CoV-2

As the COVID-19 pandemic rages across the world, killing hundreds of thousands and infecting over 4.1 million, researchers are racing against time to understand the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 genome has now been sequenced in many different regions of the world, and researchers are collaborating by sharing information to better understand the make-up and mutations that the virus has undergone.

11 May 2020

Regeneron and CCPM collaborate to advance human genetics, precision medicine

Regeneron Pharmaceuticals, Inc. and the Colorado Center for Personalized Medicine at the University of Colorado Anschutz Medical Campus today announced a large-scale research collaboration designed to advance the field of human genetics and precision medicine through the sharing of 450,000 DNA samples and corresponding health records from de-identified, consented patient participants in the expansive UCHealth system.

11 May 2020

Scientists create German COVID-19 OMICS Initiative to accelerate research

How does the new coronavirus (SARS-CoV-2) change its genetic information? What other infections occur in patients with COVID-19? Are there genetic risk factors that favor an infection? Numerous genome researchers are pooling their expertise and sequencing infrastructure to make a scientific contribution to manage the COVID-19 pandemic.

9 May 2020

Genomics Medicine Ireland supports scientists participating in global COVID-19 research efforts

Genomics Medicine Ireland announced this week that it is supporting scientists in Ireland who are participating in global research efforts into COVID-19 coronavirus which has so far killed over 200,000 people across the world.

8 May 2020

Researchers identify transcription factor that preserves the genomic integrity of germline

The germline is the cell lineage of an organism that passes on its genetic material to its progeny. Genetic damage to the germline can cause developmental defects and even death of that same progeny.

7 May 2020

Samplix introduces comprehensive service program to grant laboratory access to Xdrop technology

Today, Samplix launched its comprehensive service program to grant any laboratory access to the advantages of Xdrop™ technology.

7 May 2020

AI-enabled precision medicine may increase survival rate of patients with COVID-19-related sepsis

Data scientists from UK-headquartered AI precision medicine company, PrecisionLife, have used the Company’s proprietary AI enabled precision medicine platform to identify 59 repurposing drug candidates that could be used to develop new therapeutic strategies to increase the survival rate of patients who develop sepsis while suffering from severe COVID-19.

7 May 2020

Study discovers inhibition of SARS-CoV-2 entry priming protein by approved drug

The COVID-19 pandemic caused by the severe acute respiratory syndrome -coronavirus 2 (SARS-CoV-2) has spread to most of the world, causing millions of cases and hundreds of thousands of deaths. A new study published on the preprint server bioRxiv* shows that a protease inhibitor drug already approved by the Food and Drug Administration (FDA) could inhibit viral entry.

6 May 2020

How do betacoronaviruses evolve?

Researchers have worked on the evolution of the pathogenic strains of the betacoronaviruses including the SARS CoV-2 that has caused the COVID-19 pandemic.

6 May 2020

Spillover of more bat coronaviruses likely due to destruction of wildlife habitats

A new study available on the preprint server bioRxiv used phylogenetic analysis to demonstrate how certain groups of bats harbor multiple coronavirus lineages that are not readily transmitted across different bat taxa. However, the researchers caution that another novel human coronavirus outbreak originating from bats is imminent due to the destruction of wildlife habitats.

6 May 2020

Combination therapy trial to understand the biology, spread, treatment of COVID-19

The HonorHealth Research Institute and HonorHealth announced today the successful enrollment on a novel combination of atovaquone and azithromycin in patients with moderate-to-severe COVID-19 infection.

6 May 2020

New study shows the importance of genetic testing in people with solid tumor cancers

A new Cleveland Clinic study demonstrates the importance of genetics evaluation and genetic testing for children, adolescents and young adults with solid tumor cancers

6 May 2020

SARS-CoV-2 genome shows mutation hotspots and type-specific distribution

Now, a new study published on the preprint server bioRxiv reports on a large scale analysis of SARS-CoV-2 genomes and reveals a clonal geo-distribution and rich genetic variations.

5 May 2020

New therapeutic possibilities for treating intellectual disability in Down syndrome

A team of researchers has studied the neural basis of intellectual disability in mice with Down syndrome and has discovered that the neural networks of brain circuits relevant to memory and learning are over-activated and that the connectivity of these circuits is poor.

5 May 2020

Patients recently recovered from COVID-19 produce virus-specific antibodies

Most newly discharged patients who recently recovered from COVID-19 produce virus-specific antibodies and T cells, suggests a study published on May 3rd in the journal Immunity, but the responses of different patients are not all the same.

5 May 2020

Researchers discover new gene involved in regulating the body's cholesterol

Precision medicine has the potential to tailor treatments to a patient's unique genetic sequence. But achieving this precision -- or developing new drugs -- requires knowing which genes are involved in disease.

4 May 2020

MU researcher finds four antiviral drugs effective in inhibiting novel coronavirus

Now, a researcher at the University of Missouri has found that four antiviral drugs, including remdesivir, a drug originally developed to treat Ebola, are effective in inhibiting the replication of the coronavirus causing COVID-19.

4 May 2020

Research detects a more dangerous SARS-CoV-2 mutation

A new study published on the preprint server bioRxiv in May 2020 reports the setting up of a system to help track new mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is behind the current COVID-19 pandemic. This will help analyze mutations to find and track the spread of those that are most likely to increase the pathogenicity of the virus, either by making it easier to transmit or by enhancing its resistance to treatment.

4 May 2020

Nanostimulators can amp up stem cells' regenerative powers for muscle repair

In regenerative medicine, an ideal treatment for patients whose muscles are damaged from lack of oxygen would be to invigorate them with an injection of their own stem cells.

3 May 2020

DNA damage and inaccurate repair mechanisms jointly cause mutational signatures

Researchers at EMBL's European Bioinformatics Institute, the University of Dundee and the Wellcome Sanger Institute analysed over 2700 genomes from C. elegans worms in order to better understand the causes of mutations.

2 May 2020

Genomic News and Research

Genomic sequences from all over the world help fight SARS-CoV-2

Regeneron and CCPM collaborate to advance human genetics, precision medicine

Scientists create German COVID-19 OMICS Initiative to accelerate research

Genomics Medicine Ireland supports scientists participating in global COVID-19 research efforts

Researchers identify transcription factor that preserves the genomic integrity of germline

Samplix introduces comprehensive service program to grant laboratory access to Xdrop technology

AI-enabled precision medicine may increase survival rate of patients with COVID-19-related sepsis

Study discovers inhibition of SARS-CoV-2 entry priming protein by approved drug

How do betacoronaviruses evolve?

Spillover of more bat coronaviruses likely due to destruction of wildlife habitats

Combination therapy trial to understand the biology, spread, treatment of COVID-19

New study shows the importance of genetic testing in people with solid tumor cancers

SARS-CoV-2 genome shows mutation hotspots and type-specific distribution

New therapeutic possibilities for treating intellectual disability in Down syndrome

Patients recently recovered from COVID-19 produce virus-specific antibodies

Researchers discover new gene involved in regulating the body's cholesterol

MU researcher finds four antiviral drugs effective in inhibiting novel coronavirus

Research detects a more dangerous SARS-CoV-2 mutation

Nanostimulators can amp up stem cells' regenerative powers for muscle repair

DNA damage and inaccurate repair mechanisms jointly cause mutational signatures

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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