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Common anti-inflammatory drug could combat deadly gut fungus, study finds

A team of UC Davis Health researchers discovered that a common anti-inflammatory drug, mesalamine, can replace the work of good bacteria in fighting the nasty fungus Candida albicans in the gut.

4 Jun 2024

Wistar scientists develop Persistent Multivalent T Cell Engager for advanced kidney cancer

Advanced clear cell renal cell carcinoma (ccRCC) is a deadly form of kidney cancer with few treatment options; even with new immunotherapies, only around one in 10 patients ultimately survive.

4 Jun 2024

Proteomic profiling reveals sexual dimorphism and immune system alterations in Werner syndrome

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, "Integrated liver and serum proteomics uncover sexual dimorphism and alteration of several immune response proteins in an aging Werner syndrome mouse model."

4 Jun 2024

Headband meditation may offer pain relief and improved function after Cushing's surgery

Patients with Cushing's syndrome who are recovering from surgery and wear a headband that tracks brain activity while they meditate may have less pain and better physical functioning compared with patients not using the device, suggests a study being presented Monday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

3 Jun 2024

Two diabetes medications more beneficial in preventing major cardiovascular events

GLP-1 receptor agonists (GLP-1s) and SGLT-2 inhibitors lower the risk of major cardiovascular events like heart attacks and severe liver complications compared to other diabetes treatments, according to data being presented Sunday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

3 Jun 2024

Insurance denials hinder GLP1Ra use in children and teens with type 2 diabetes

Health insurance companies often deny coverage for new medications that treat children and teens with obesity and type 2 diabetes, meaning many patients who need treatment are unable to afford it, according to a study presented at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

3 Jun 2024

GLP-1 drugs may reduce pancreatitis risk in obese and diabetic patients

Medications for type 2 diabetes and obesity known as GLP-1 receptor agonists may lower the risk of acute pancreatitis recurrence in people with obesity and those with type 2 diabetes, according to a study presented Saturday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

3 Jun 2024

Experimental treatment for metastatic pancreatic cancer shows promise in phase 2 clinical trial

Clinicians at Georgetown University's Lombardi Comprehensive Cancer Center reported promising preliminary findings based on outcomes in the first six patients with metastatic pancreatic cancer enrolled in a phase 2 clinical trial of the experimental drug BXCL701 in combination with the immunotherapy drug pembrolizumab (Keytruda).

3 Jun 2024

DefiniGEN and Atelerix collaborate to ship in vitro cell models internationally without the need for freezing or cryopreservation

DefiniGEN Ltd., and Atelerix Ltd., today announced they have successfully shipped in vitro liver models from the UK to a top tier pharma customer in the US. The agreement between the companies combines DefiniGEN’s mechanistically relevant iPSC hepatocytes (Opti-Heps) with Atelerix's hydrogel preservation technology, which prevents loss of function and enables even sensitive samples to remain stable at ambient temperatures for up to two weeks.

From Defini Gen 3 Jun 2024

Canagliflozin enhances senescent cell clearance, improving aging-related conditions

Whether sodium-glucose co-transporter 2 (SGLT2) inhibitors induce senolysis.

3 Jun 2024

New treatment approach could offer longer lasting protection to people with breast cancer

Killing breast cancer cells in a way that trains the immune system to recognize and destroy residual cancer cells could offer longer lasting protection to people with the disease, according to new research funded by Breast Cancer Now.

3 Jun 2024

Space experiment offers new path to fighting osteoarthritis

More than 650 million people worldwide are affected by osteoarthritis, and few treatment options exist. However, new promising results from an International Space Station (ISS) National Laboratory-sponsored experiment detail a tissue chip model that accurately reproduces the conditions under which post-traumatic osteoarthritis (PTOA) is initiated. Published in Frontiers in Space in March, these findings mark an important step forward in understanding and testing treatments for the underlying causes of osteoarthritis and related conditions.

3 Jun 2024

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Liquid foam gene delivery significantly enhances transfection efficiency and safety, offering a cost-effective alternative to conventional methods.

3 Jun 2024

Garlic proves potent in reducing blood sugar and cholesterol, study reveals

Study confirms garlic's significant benefits in lowering blood glucose and lipid levels, offering a natural remedy for metabolic disorders.

2 Jun 2024

Precision medicine doubles progression-free survival in young cancer patients

Cancer is the leading cause of disease-related death in children in most developed countries, and at least a quarter of these patients are diagnosed with aggressive high-risk or relapsed cancers, with an expected five-year survival rate of less than 30%.

31 May 2024

Drugs News and Research

Common anti-inflammatory drug could combat deadly gut fungus, study finds

Wistar scientists develop Persistent Multivalent T Cell Engager for advanced kidney cancer

Proteomic profiling reveals sexual dimorphism and immune system alterations in Werner syndrome

Headband meditation may offer pain relief and improved function after Cushing's surgery

Two diabetes medications more beneficial in preventing major cardiovascular events

Insurance denials hinder GLP1Ra use in children and teens with type 2 diabetes

GLP-1 drugs may reduce pancreatitis risk in obese and diabetic patients

Experimental treatment for metastatic pancreatic cancer shows promise in phase 2 clinical trial

DefiniGEN and Atelerix collaborate to ship in vitro cell models internationally without the need for freezing or cryopreservation

Canagliflozin enhances senescent cell clearance, improving aging-related conditions

New treatment approach could offer longer lasting protection to people with breast cancer

Space experiment offers new path to fighting osteoarthritis

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Garlic proves potent in reducing blood sugar and cholesterol, study reveals

Precision medicine doubles progression-free survival in young cancer patients

Integrating PGx testing for personalized prostate cancer treatment

Super-resolution microscopy offers high-resolution view of virus replication inside cells

New vessel-chip deployment platform holds promise for personalized drug testing

Mindfulness as medicine: A powerful tool for pain and addiction

VUMC researchers discover potent antibody against influenza B

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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