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FDA approves first drug for treatment of adult AML patients with specific genetic mutation

The U.S. Food and Drug Administration today approved Tibsovo (ivosidenib) tablets for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) who have a specific genetic mutation.

20 Jul 2018

AbbVie submits supplemental NDA to FDA for venetoclax to treat acute myeloid leukemia

AbbVie, a research-based global biopharmaceutical company, today announced it submitted a supplemental New Drug Application to the U.S. Food and Drug Administration for venetoclax in combination with a hypomethylating agent or in combination with low-dose cytarabine for the treatment of newly diagnosed patients with acute myeloid leukemia who are ineligible for intensive chemotherapy.

20 Jul 2018

Older people with broken bones face higher risk of death for up to 10 years

Broken bones among older people increase their risk of death for up to 10 years, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

19 Jul 2018

New Finnish study compares surgical treatment of shoulder impingement syndrome to placebo surgery

In a landmark study published this week in the BMJ, Finnish researchers show that one of the most common surgical procedures in the Western world is probably unnecessary.

19 Jul 2018

Phase 3 study of tanezumab in patients with osteoarthritis pain meets all three co-primary endpoints

Pfizer Inc. and Eli Lilly and Company today announced that a 16-week Phase 3 study in patients with osteoarthritis pain evaluating subcutaneous administration of tanezumab, an investigational humanized monoclonal antibody, met all three co-primary endpoints.

19 Jul 2018

Children with disabilities endure long waits for life-changing medical equipment

Bev Baker-Ajene waited so long to get an adult-sized wheelchair for her teenage daughter, Savitri, that she eventually forgot she'd ordered it.

19 Jul 2018

Researchers unravel how ALL invades the central nervous system

A deadly feature of acute lymphoblastic leukemia is its invasion of the central nervous system.

19 Jul 2018

Prolonged preoperative opioid use linked to adverse outcomes after total knee and hip arthroplasty

Patients who take prescription opioids for more than 60 days before total knee or hip replacement surgery are at significantly higher risk of being readmitted to the hospital and of undergoing repeat joint-replacement surgery, compared to patients with no preoperative opioid use, reports a study in the July 18 issue of The Journal of Bone & Joint Surgery.

19 Jul 2018

New technique allows researchers to create large scale, personalized bone grafts

Scientists from the New York Stem Cell Foundation Research Institute have developed a new bone engineering technique called Segmental Additive Tissue Engineering.

18 Jul 2018

Novel bioengineering technique could help repair bone defects

Researchers have developed a bone engineering technique that uses stem cells to improve bone grafts for the treatment of bone injury or disease.

18 Jul 2018

New study demonstrates little effect of hormone therapy on artery thickness

Heart disease is still the number one killer of US women, and hormone therapy remains a top treatment for menopause symptoms.

18 Jul 2018

CT scans may raise brain tumor risk

A new study in the Journal of the National Cancer Institute suggests that CT scans, commonly used in medical imaging, may increase the risk of brain tumors.

18 Jul 2018

Vallum receives FDA clearance to market PEEK spinal interbody fusion device

Vallum Corporation, a medical device company, today announced that it has received clearance from the U.S. Food and Drug Administration to market a polyetheretherketone spinal interbody fusion device with a PEEKplus nanotextured surface created by Vallum's proprietary and patented Accelerated Neutral Atom Beam technology.

17 Jul 2018

Homogenous BTK occupancy assay used in tirabrutinib clinical studies

In a new SLAS Discovery article, Helen Yu and a team of researchers at Gilead Sciences, Inc. present a time-resolved fluorescence resonance energy transfer-based Bruton's tyrosine kinase occupancy assay that can measure target engagement in peripheral blood mononuclear cells and in lymph-node and bone-marrow samples.

17 Jul 2018

Researchers map family trees of cancer cells to understand how AML responds to new drug

For the first time, a team of international researchers have mapped the family trees of cancer cells in acute myeloid leukemia to understand how this blood cancer responds to a new drug, enasidenib.

17 Jul 2018

Electronic system to speed up facial pain diagnosis may improve quality of life and save money

Patients with persistent facial pain are costing the economy more than £3,000 each per year, new research has revealed.

17 Jul 2018

Researchers reduce size of tumors in mice by artificially activating the brain's reward system

By artificially activating the brain's reward system, researchers at the Technion-Israel Institute of Technology have dramatically reduced the size of cancerous tumors in mice. The findings were published recently in the journal Nature Communications.

16 Jul 2018

Bone News and Research

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

AbbVie submits supplemental NDA to FDA for venetoclax to treat acute myeloid leukemia

Older people with broken bones face higher risk of death for up to 10 years

New Finnish study compares surgical treatment of shoulder impingement syndrome to placebo surgery

Phase 3 study of tanezumab in patients with osteoarthritis pain meets all three co-primary endpoints

Children with disabilities endure long waits for life-changing medical equipment

Researchers unravel how ALL invades the central nervous system

Prolonged preoperative opioid use linked to adverse outcomes after total knee and hip arthroplasty

New technique allows researchers to create large scale, personalized bone grafts

Novel bioengineering technique could help repair bone defects

New study demonstrates little effect of hormone therapy on artery thickness

CT scans may raise brain tumor risk

Vallum receives FDA clearance to market PEEK spinal interbody fusion device

Homogenous BTK occupancy assay used in tirabrutinib clinical studies

Researchers map family trees of cancer cells to understand how AML responds to new drug

Electronic system to speed up facial pain diagnosis may improve quality of life and save money

Researchers reduce size of tumors in mice by artificially activating the brain's reward system

Study highlights potential of fetal gene therapy to prevent lethal neurodegenerative disease

University of Illinois buys 3D-Bioplotter for regenerative biology, tissue engineering research

Study: Football training could improve bone mineral density in prostate cancer patients

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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