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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Proteomics approach helps identify protein signatures that can improve detection of prediabetes

Scientists have used a proteomics approach to identify a three-protein signature in the blood that can improve detection of isolated impaired glucose tolerance, a form of prediabetes.

10 Nov 2022

Study illuminates how a typical gut bacterium spreads through the body

A typical gut bacterium that can spread through the body and cause a serious infection resists natural immune defenses and antibiotics by enhancing its protective outer layer, known as the cell envelope, according to a new study by Weill Cornell Medicine investigators.

10 Nov 2022

High-quality reference genome assembly of the Nile rat facilitates diabetes research

Model organisms are essential for biomedical research and have enabled many important scientific discoveries. The ability to sequence the genomes of these models is a powerful tool to study the genetic factors that impact human health.

9 Nov 2022

New tool maps how breast cancer grows in previously unseen detail

New technology can trace which populations of breast cancer cells are responsible for the spread of the disease, and for the first time highlights how the location of cancer cells could be as important as mutations in tumor growth.

9 Nov 2022

What are the eye complications associated with monkeypox infection?

A new study describes the association between monkeypox infection and eye complications in humans.

9 Nov 2022

What is the role of adenoviruses in human health?

With advances in molecular biology informing recent developments in vaccinology, gene therapy, and other fields of medicine, human adenoviruses (HAdVs) have been of primary importance in medical research. A recent review looks at the promises of HAdVs, their potential dangers, and future challenges.

9 Nov 2022

Scientists determine 5,072 essential human genes

In a recent study published in the journal Cell, researchers examined the phenotypic landscape of multiple elusive essential human genes to create a detailed genotype-phenotype resource outlining the phenotypic consequences of disrupting fundamental cellular processes.

8 Nov 2022

Protein complex may present strong therapeutic target for lethal breast cancer

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have shown that a protein complex that governs gene expression (called CoREST) sometimes gets rewired during breast cancer to help estrogen receptor positive (ER+) tumors resist endocrine therapies and become more aggressive.

8 Nov 2022

Study shows the added value of genetic information in measuring inherited disease risk

A new study from the University of Helsinki demonstrates the added value of genetic information in measuring inherited disease risk, alongside the widely used assessment of family history.

8 Nov 2022

Researchers unravel genetic changes in a region that controls the activity of the genome

Scientists have discovered the cause of a rare condition within a part of the genome that has been largely unexplored in medical genetics. A team at the University of Exeter has found genetic changes in a region that controls the activity of the genome, turning on or off genes, and in doing so they have found a key that could unlock other causes of rare conditions.

8 Nov 2022

Study confirms the implication of Mib1 mutations in non-compaction cardiomyopathy

Non-compaction cardiomyopathy is a heart condition caused by defects that arise during fetal development and can have diverse health impacts in affected individuals, including sudden cardiac death.

7 Nov 2022

Viral whole genome study in the United States identifies ORF-disrupting mutations in monkeypox virus

Researchers used whole genome sequencing to evaluate monkeypox virus samples from Washington and Ohio states in the United States and identified 25 samples with open reading frame (ORF)-disrupting mutations.

7 Nov 2022

Phylodynamic analysis of the monkeypox virus genome suggests low genetic variation and evolutionary rates

Researchers explored the genetic variability among the monkeypox virus genomes of Clade IIb lineage B.1 using a phylodynamic and genetic survey to confirm the epidemic cluster in the clade and understand the evolution of the virus.

7 Nov 2022

Chromosomal microarray analysis could help identify the cause of SIDS or SUDC in older children

A genetic test known as chromosomal microarray analysis (CMA) could help identify the cause of sudden infant death syndrome (SIDS) or its counterpart in older children, known as sudden unexplained death in childhood (SUDC), finds a study led by Boston Children's Hospital.

7 Nov 2022

DNA barcoding shows how cancer cells evade the immune system's defenses

Some cancer cells can deploy parallel mechanisms to evade the immune system's defences as well as resist immunotherapy treatment, according to a new study from the Garvan Institute of Medical Research.

7 Nov 2022

Personalized whole genome sequencing approach could double the diagnostic rates of rare diseases

Tailoring the analysis of whole genome sequencing to individual patients could double the diagnostic rates of rare diseases, finds a new study led by UCL researchers.

7 Nov 2022

Developing art and creativity to help fight cancer

Developing art and creativity to improve the effectiveness and delivery of healthcare. From narrative medicine to the disclosure of one's medical records on the net: how "open sourcing" feelings and fears can help fight cancer and reshape the concept of "cure".

4 Nov 2022

DNA News and Research

Further Reading

Proteomics approach helps identify protein signatures that can improve detection of prediabetes

Study illuminates how a typical gut bacterium spreads through the body

High-quality reference genome assembly of the Nile rat facilitates diabetes research

New tool maps how breast cancer grows in previously unseen detail

What are the eye complications associated with monkeypox infection?

What is the role of adenoviruses in human health?

Scientists determine 5,072 essential human genes

Protein complex may present strong therapeutic target for lethal breast cancer

Study shows the added value of genetic information in measuring inherited disease risk

Researchers unravel genetic changes in a region that controls the activity of the genome

Study confirms the implication of Mib1 mutations in non-compaction cardiomyopathy

Viral whole genome study in the United States identifies ORF-disrupting mutations in monkeypox virus

Phylodynamic analysis of the monkeypox virus genome suggests low genetic variation and evolutionary rates

Chromosomal microarray analysis could help identify the cause of SIDS or SUDC in older children

DNA barcoding shows how cancer cells evade the immune system's defenses

Personalized whole genome sequencing approach could double the diagnostic rates of rare diseases

Developing art and creativity to help fight cancer

Charles River Laboratories: New Center Expands Cell and Gene Therapy Capabilities

Specific mutations in the monkeypox virus contribute to its continued infectiousness

Novel monoclonal antibodies NA8 and NE12 can neutralize most SARS-CoV-2 variants and Omicron subvariants

Understanding the DNA Damage Response in Innate Immunity eBook

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