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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

New breakthrough in understanding how deletion of certain genes can lead to cancer growth

Genetic mutations kick start cancers. Some mutations shuffle the genetic code, others come from the deletion of key genes.

28 Oct 2022

Proof-of-principle study: Novel tool advances potential way to deliver gene therapy

Johns Hopkins Medicine researchers say they have successfully used a cell's natural process for making proteins to "slide" genetic instructions into a cell and produce critical proteins missing from those cells.

28 Oct 2022

Commensal gut microbes from IBD patients produce genotoxic metabolites

Functional screening of human gut microbiota reveals a family of small molecule genotoxins called indolimines in patients with inflammatory bowel disease (IBD), according to a new study.

27 Oct 2022

Ancient viral DNA in human genomes protects cells against present-day viruses

Viral DNA in human genomes, embedded there from ancient infections, serve as antivirals that protect human cells against certain present-day viruses, according to new research.

27 Oct 2022

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

Researchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have used CRISPR/Cas9 technology to engineer donor T cells to try to treat seriously ill children with resistant leukaemia, who had otherwise exhausted all available therapies.

27 Oct 2022

Study sheds light on why some patients respond better than others to immunotherapy

Immunotherapy, a biotherapy that boosts the ability of the immune system to recognize and attack mutant tumor cells, has transformed the treatment landscape for patients battling cancer, which emerges from the progressive accumulation of DNA mutations.

27 Oct 2022

Researchers find a switch to regulate the diabetes-causing gene

Researchers at the Centre for Genomic Regulation and Imperial College London have found a switch that regulates the activity of a gene that causes diabetes.

27 Oct 2022

Research opens up new avenues for overcoming treatment resistance in colorectal cancer

Colorectal cancer is one of the most common cancers. Its treatment is mainly based on chemotherapy. However, over time, chemotherapy induces resistance in the majority of patients, who end up being unresponsive to the drugs.

27 Oct 2022

Advanced type of nanoparticle could help fight hard-to-treat cancers

Nanoparticles, or tiny molecules that can deliver a payload of drug treatments and other agents, show great promise for treating cancers.

27 Oct 2022

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

A fault in cells that form a key part of the immune system can be repaired with a pioneering gene editing technique, finds new research demonstrated in human cells and mice, led by UCL scientists.

27 Oct 2022

Study finds that ACE-2 is not biochemically required for SARS-CoV2 membrane fusion

A study tested the hypothesis that the ACE-2 receptor of SARS-CoV-2 is not only an attachment factor in viral infection but also plays a role in activating the viral spike protein to facilitate membrane fusion.

27 Oct 2022

What parents need to know about prenatal tests | BGI Perspectives

The birth of every new life is to be celebrated! Expecting parents often advised by doctors from the department of gynecology and obstetrics to consider noninvasive prenatal tests (NIPT).

From BGI Genomics 26 Oct 2022

COVID-19 and the gut

Researchers summarize current knowledge about underlying mechanisms and potential therapeutic approaches for the effects of COVID-19 on the gut.

26 Oct 2022

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Impaired DNA repair capacity among elderly increases expression of ACE2 receptor.

26 Oct 2022

Study offers a combination treatment option for patients with oligometastatic prostate cancer

A new study offers a new option to patients with oligometastatic prostate cancer who want relief from hormone therapy without compromising the risk of their disease spreading.

25 Oct 2022

Researchers focus on the identification of markers to improve head and neck cancer risk assessment

Malignant tumors in the head and neck region are very heterogeneous and therefore difficult to treat. In addition, the lack of prognostic markers is a significant impediment to personalized treatment.

25 Oct 2022

Genomic rearrangements in monkeypox virus could be a sign of adaption to the human host

Researchers explored genomic rearrangements in monkeypox virus genomes and investigated whether such rearrangements represented viral adaption to humans (host).

25 Oct 2022

MSU researchers receive $3 million NIH grant to study testosterone’s role in depression

Major depressive disorder affects women twice as often as men, but researchers are still trying to identify the reasons why.

24 Oct 2022

Variations in low-complexity regions in monkeypox genome found to impact virus transmissibility

In a new study, researchers investigated whether low-complexity regions (LCRs) were more accountable for the current 2022 IIb clade monkeypox (MPX) virus (MPXV) outbreak rather than single-nucleotide polymorphisms (SNPs).

24 Oct 2022

Investigating the evidence of synthetic origins of SARS-CoV-2

Researchers investigated whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) originated naturally from an animal-to-human spillover or synthetically during coronavirus research experiments.

24 Oct 2022

DNA News and Research

Further Reading

New breakthrough in understanding how deletion of certain genes can lead to cancer growth

Proof-of-principle study: Novel tool advances potential way to deliver gene therapy

Commensal gut microbes from IBD patients produce genotoxic metabolites

Ancient viral DNA in human genomes protects cells against present-day viruses

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

Study sheds light on why some patients respond better than others to immunotherapy

Researchers find a switch to regulate the diabetes-causing gene

Research opens up new avenues for overcoming treatment resistance in colorectal cancer

Advanced type of nanoparticle could help fight hard-to-treat cancers

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

Study finds that ACE-2 is not biochemically required for SARS-CoV2 membrane fusion

What parents need to know about prenatal tests | BGI Perspectives

COVID-19 and the gut

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Study offers a combination treatment option for patients with oligometastatic prostate cancer

Researchers focus on the identification of markers to improve head and neck cancer risk assessment

Genomic rearrangements in monkeypox virus could be a sign of adaption to the human host

MSU researchers receive $3 million NIH grant to study testosterone’s role in depression

Variations in low-complexity regions in monkeypox genome found to impact virus transmissibility

Investigating the evidence of synthetic origins of SARS-CoV-2

Understanding the DNA Damage Response in Innate Immunity eBook

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