Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Vanderbilt researchers isolate antibody that can neutralize West Nile virus

Researchers at Vanderbilt University Medical Center and colleagues have isolated a human monoclonal antibody that can "neutralize" the West Nile virus and potentially prevent a leading cause of viral encephalitis (brain inflammation) in the United States.

21 Nov 2018

Researchers discover new information on pathological mechanisms of Alzheimer's disease

Researchers at the University of Helsinki have discovered a mechanism by which harmful tau protein aggregates are transmitted between neurons. Alongside amyloid plaques, tau aggregates in the brain are a significant factor in the progression of Alzheimer's disease.

20 Nov 2018

Researchers have trained a computer to analyze breast cancer images and classify tumors

Using technology similar to the type that powers facial and speech recognition on a smartphone, researchers at the University of North Carolina Lineberger Comprehensive Cancer Center have trained a computer to analyze breast cancer images and then classify the tumors with high accuracy.

19 Nov 2018

Researchers develop new drug molecule that inhibits inflammation

A multidisciplinary team of researchers led from Karolinska Institutet in Sweden have developed an anti-inflammatory drug molecule with a new mechanism of action.

15 Nov 2018

Researchers discover molecular basis for therapeutic actions of an African folk medicine

Researchers in the Department of Physiology & Biophysics at the University of California, Irvine School of Medicine have discovered the molecular basis for therapeutic actions of an African folk medicine used to treat a variety of illnesses and disorders including diabetes, pain, headaches, paralysis and epilepsy.

15 Nov 2018

St. Jude Hospital announces availability of largest collections of leukemia samples

St. Jude Children's Research Hospital today announced the availability of one of the world's largest collections of leukemia samples from children and adults.

15 Nov 2018

NIH awards $3.4 million to UC researchers to study gastrointestinal lymphatic system

A team of researchers at the University of Cincinnati College of Medicine have been awarded $3.4 million by the National Institutes of Health to study the role of the gastrointestinal lymphatic system in dietary nutrient absorption and the transport of signaling molecules.

15 Nov 2018

Promising technology could improve detection, diagnosis of fatal ovarian cancer

Ovarian cancer claims the lives of more than 14,000 in the U.S. each year, ranking fifth among cancer deaths in women.

14 Nov 2018

Researchers evaluate efficacy of salivary biomarkers for early detection of oral cancer

Over 90% of malign tumors in the head and neck are originated from carcinomas of squamous cells that appear in superficial areas of the oral cavity. Their detection with salivary biomarkers can contribute to their early treatment, before they transform into tumors.

14 Nov 2018

Inhibition of one protein clears toxic clumps seen in Parkinson's disease, study finds

A defining feature of Parkinson's disease is the clumps of alpha-synuclein protein that accumulate in the brain's motor control area, destroying dopamine-producing neurons.

14 Nov 2018

Study identifies potential therapeutic strategy for patients with clear cell renal cancer

Researchers have provided new insight on the mechanisms behind the development of clear cell Renal Cell Carcinoma (ccRCC), according to new findings published in eLife.

13 Nov 2018

Advanced AI and big data methods to tackle dementia

Sports concussions, Parkinson's disease, and hormone therapy for cancer - all can have memory loss as symptoms. But do the biochemical processes of each type of memory loss have anything to reveal about the memory loss that is part of Alzheimer's disease?

13 Nov 2018

Transgenic rat model may provide new insights into cerebral amyloid angiopathy

In a report in The American Journal of Pathology investigators describe the generation of a successful novel transgenic rat model that accumulates amyloid specifically in brain blood vessels and strongly mimics many of the associated detrimental changes that are observed in humans - a condition known as cerebral amyloid angiopathy, which is also commonly observed in Alzheimer disease.

13 Nov 2018

Gladstone scientists gain new insights into the aging brain

The protein klotho has been shown to promote longevity and counteract aging-related impairments. Having more klotho seems to allow for longer and healthier lives, whereas a depletion of this molecule accelerates aging and may contribute to age-related diseases.

12 Nov 2018

Study shows novel strategy to reduce breast cancer bone metastasis

Uncovering a novel mechanism that promotes growth of breast cancer bone metastasis has revealed a potential Achilles' heel for these cancer cells. Reported in the journal Cancer Cell, the study shows that interfering with this mechanism can reduce the risk of relapses in animal models.

12 Nov 2018

Growth and spread of deadly eye tumor suppressed in cells, animals

By comparing genetic sequences in the eye tumors of children whose cancers spread with tumors that didn't spread, Johns Hopkins Medicine researchers report new evidence that a domino effect in cells is responsible for the cancer spreading.

12 Nov 2018

Shortage of specific gene 'silencing' molecules linked with pediatric low-grade gliomas

Experimenting with lab-grown brain cancer cells, Johns Hopkins Medicine researchers have added to evidence that a shortage of specific tiny molecules that silence certain genes is linked to the development and growth of pediatric brain tumors known as low-grade gliomas.

12 Nov 2018

Fecal microbiota transplantation effective against ICI-associated colitis

For the first time, transplanting gut bacteria from healthy donors was used to successfully treat patients suffering from severe colitis caused by treatment with immune checkpoint inhibitors.

12 Nov 2018

Mild exposure to single blast can induce meaningful pathogenic effects, study shows

As many as 300,000 United States service members deployed to Iraq and Afghanistan since 2001 have suffered traumatic brain injury due to explosions. The vast majority of these blast-induced traumatic brain injuries, or bTBIs, were classified as mild.

12 Nov 2018

Cardiovascular and Alzheimer's disease share common genetics in some individuals, study shows

Genetics may predispose some people to both Alzheimer's disease and high levels of blood lipids such as cholesterol, a common feature of cardiovascular disease, according to a new study by an international team of researchers led by scientists at UC San Francisco and Washington University School of Medicine in St. Louis.

9 Nov 2018

Pathology News and Research

Further Reading

Vanderbilt researchers isolate antibody that can neutralize West Nile virus

Researchers discover new information on pathological mechanisms of Alzheimer's disease

Researchers have trained a computer to analyze breast cancer images and classify tumors

Researchers develop new drug molecule that inhibits inflammation

Researchers discover molecular basis for therapeutic actions of an African folk medicine

St. Jude Hospital announces availability of largest collections of leukemia samples

NIH awards $3.4 million to UC researchers to study gastrointestinal lymphatic system

Promising technology could improve detection, diagnosis of fatal ovarian cancer

Researchers evaluate efficacy of salivary biomarkers for early detection of oral cancer

Inhibition of one protein clears toxic clumps seen in Parkinson's disease, study finds

Study identifies potential therapeutic strategy for patients with clear cell renal cancer

Advanced AI and big data methods to tackle dementia

Transgenic rat model may provide new insights into cerebral amyloid angiopathy

Gladstone scientists gain new insights into the aging brain

Study shows novel strategy to reduce breast cancer bone metastasis

Growth and spread of deadly eye tumor suppressed in cells, animals

Shortage of specific gene 'silencing' molecules linked with pediatric low-grade gliomas

Fecal microbiota transplantation effective against ICI-associated colitis

Mild exposure to single blast can induce meaningful pathogenic effects, study shows

Cardiovascular and Alzheimer's disease share common genetics in some individuals, study shows

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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