Lymph Node News and Research

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Lymph is clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean. After passing through the channels of the lymphatic system they drain into the lymph nodes. The lymph nodes act as filters along the lymphatic system. These nodes trap germs like bacteria, viruses, toxins as well as cancer cells and ensure that these are removed from the body.

Two cell types partner to protect pancreatic tumors from immune attack

Two cell types work together to protect pancreatic tumors from destruction by the immune system. But, blocking this partnership may restore the system's ability to attack these same tumor cells.

19 Jul 2017

Lymph node removal may not be needed for all melanoma patients, study finds

Many patients with melanoma need a sentinel-lymph-node biopsy to determine if cancer cells have spread there, but a positive finding doesn't mean all the lymph nodes in the area must be removed, according to new international study.

17 Jul 2017

Cancer metastases may originate from primary tumor without involving lymph system

Research by several leading scientists including Rakesh Jain, PhD, Director of the Edwin L. Steele Laboratory for Tumor Biology at the Massachusetts General Hospital and supported in part by the National Foundation for Cancer Research, has provided the first evidence that the century-old model for cancer metastasis - where cancer spreads from primary tumor to nearby lymph nodes, and then to other organs - may not apply in all cases.

13 Jul 2017

Study: Postponing lymph node biopsy after melanoma diagnosis does not affect long-term outcomes

Postponing lymph node biopsy more than 30 days after melanoma diagnosis doesn't adversely impact long-term clinical outcomes, according to new study findings published online as an "article in press" on the Journal of the American College of Surgeons website ahead of print publication.

28 Jun 2017

Two further cases of plague reported in Santa Fe, New Mexico

The New Mexico Department of Health (NMDOH) has reported two new cases of plague infecting a 52- year old woman and a 62-year old woman, in the Santa Fe County.

28 Jun 2017

Study emphasizes importance of molecule in maintaining balanced immune system in the gut

A healthy gut requires a molecule called gp96 to train the immune system to tolerate food and normal microbes, report researchers at the Medical University of South Carolina in the May 19, 2017 issue of Scientific Reports.

14 Jun 2017

Study shows effectiveness of 3 months of chemotherapy in colon cancer patients after surgery

After surgery for lymph-node positive colon cancer (stage III), some patients may only need half of the long-standing standard course of chemotherapy.

5 Jun 2017

Study identifies two T cell biomarkers that may predict survival trajectory of IPF patients

Two T cell biomarkers appear to predict the survival trajectory of patients with idiopathic pulmonary fibrosis (IPF), a lung disease that has a varied, but ultimately devastating, impact on patients, according to new research presented at the ATS 2017 International Conference.

22 May 2017

Traveling to academic medical center for surgical removal of pancreatic cancer linked to longer survival

New study findings link traveling to an academic medical center for surgical removal of pancreatic or thyroid cancer with higher quality surgical care for both cancers, and longer survival for patients with pancreatic cancer compared with patients who receive treatment at a hospital closer to home.

2 May 2017

Study finds shorter course of radiation therapy given after mastectomy to be safe and effective

A shorter course of radiation therapy given to breast cancer patients following mastectomy is safe and effective and cuts treatment time in half. That is according to data from a phase II clinical trial conducted by Rutgers Cancer Institute of New Jersey investigators and other colleagues who examined a hypofractionated regimen given over three weeks versus the traditional six week course of treatment.

2 May 2017

AI key to driving precision medicine in cancer?

It is worth noting that in the U.S. and in many countries, digital pathology is still at a very early stage, compared to many other fields that were digitized 15 or 20 years ago such as radiology. There have been some barriers to the adoption of digital pathology such as regulatory challenges that are only just now being overcome. Recently, the FDA approved the use of whole slide imaging software for primary diagnostics.

27 Apr 2017

Combined treatment regimen shows early promise in eliminating metastatic prostate cancer

In the past, all forms of metastatic prostate cancer have been considered incurable. In recent years, the FDA has approved six drugs for men with metastatic disease, all of which can increase survival.

18 Apr 2017

Targeting cancer stem cells may be effective way to prevent spread of squamous cell carcinoma

Targeting cancer stem cells may be a more effective way to overcome cancer resistance and prevent the spread of squamous cell carcinoma — the most common head and neck cancer and the second-most common skin cancer, according to a new study by cancer researchers at the UCLA School of Dentistry.

10 Mar 2017

Study identifies sentinel-lymph-node mapping as safe, accurate way to stage endometrial cancer

Emma Rossi, MD, in the UNC Department of Obstetric and Gynecology's Division of Gynecologic Oncology, has published a study in Lancet Oncology online that identifies sentinel-lymph-node mapping as a safer and less-invasive method of staging endometrial cancer that is equally as accurate as the more traditional lymphadenectomy.

21 Feb 2017

Proscia collaborates with Samsung Medical Center to develop tools for metastasis prediction in lung cancer

Proscia Inc., a data solutions provider for digital pathology, and Samsung Medical Center, South Korea’s preeminent clinical and biomedical research institute, today announced a partnership focused on developing tools that enable predictive medicine in the fight against cancer.

16 Feb 2017

Experts establish first set of diagnostic criteria for life-threatening idiopathic multicentric CD

More than six decades after Castleman disease was first described, a group of experts from Penn Medicine and other institutions around the world has established the first set of diagnostic criteria for a life-threatening subtype of the condition, idiopathic multicentric CD, which is often misdiagnosed as other illnesses.

16 Feb 2017

Drug given to reduce side effects of pain medication may facilitate gastrointestinal recovery after testicular cancer surgery

Post-operative recovery and length of hospital stay are critical things to consider when having major surgery. A drug commonly given to reduce the side effects of strong post-surgery pain medications has been found to reduce the length of hospital stays for patients who have undergone major gastrointestinal or bladder cancer procedures.

15 Feb 2017

Study explores links between genetic susceptibility and heterogeneous phenotypes of lymphedema

Each year, about 1.38 million women worldwide are diagnosed with breast cancer. Advances in diagnosis and treatment have facilitated a 90-percent, five-year survival rate, among those treated.

9 Feb 2017

Scientists develop 3-D organoid to unravel immune response during infection

What if you could design an adaptable, biomaterials-based model of an organ to track its immune response to any number of maladies, including cancer, transplant rejection and the Zika virus? The lab of Ankur Singh, assistant professor in the Sibley School of Mechanical and Aerospace Engineering, has asked - and begun to answer - that very question.

6 Jan 2017

Study shows promising results for treating lymphoma patients with immune cell therapy

Lymphoma is the most common blood cancer. The disease occurs when immune cells called lymphocytes multiply uncontrollably. Cancerous lymphocytes can travel throughout the body and form lymph node tumors.