Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Scientists find new way to produce brain cells from single iPSC

Li Gan, PhD, wants to find treatments to help patients with Alzheimer's disease. Like most researchers, she's hit a few major roadblocks.

10 Oct 2017

Patients unaware of memory loss more likely to develop Alzheimer's disease, study shows

While memory loss is an early symptom of Alzheimer's disease, its presence doesn't mean a person will develop dementia. A new study at the Centre for Addiction and Mental Health has found a clinically useful way to predict who won't develop Alzheimer's disease, based on patients' awareness of their memory problems.

10 Oct 2017

Scientists show how a trio of key molecules directs learning and memory

Learning and memory are two important functions of the brain that are based on the brain's plasticity. Scientists from Goethe University Frankfurt report in the latest issue of the scientific journal "Cell Reports" how a trio of key molecules directs these processes.

9 Oct 2017

Alzheimer's gene can protect against and promote neurological damage

Scientists drilling down to the molecular roots of Alzheimer's disease have encountered a good news/bad news scenario. A major player is a gene called TREM2, mutations of which can substantially raise a person's risk of the disease.

9 Oct 2017

New $7.6 million NIA grant awarded to IU for Longitudinal Early-onset AD Study

Indiana University School of Medicine has been awarded a one-year, $7.6 million grant from the National Institute on Aging to establish a network of sites to study early-onset Alzheimer's disease.

9 Oct 2017

Researchers propose LSD1 protein as central player in Alzheimer's and FTD

Removal of a regulatory gene called LSD1 in adult mice induces changes in gene activity that that look unexpectedly like Alzheimer's disease, scientists have discovered.

9 Oct 2017

Powerful clot-busting drugs found safe for treating stroke patients with dementia

Stroke patients with dementia treated with intravenous thrombolysis using powerful clot-busting drugs are at no higher risk of brain hemorrhage or death than other patients receiving the same treatment, a study from Karolinska Institutet published in the journal Neurology reports.

9 Oct 2017

Study captures economic burden of frontotemporal degeneration in the United States

You may not have heard of it, but frontotemporal degeneration (FTD) accounts for 20 to 50 percent of dementia cases in people under the age of 65. FTD ravages an individual's quality of life by dramatically altering their language, personality, behavior, cognition and motor function. But it doesn't end there.

4 Oct 2017

Women with high blood pressure in their 40s may more likely develop dementia later

Women who develop high blood pressure in their 40s may be more likely to develop dementia years later, according to a study published in the October 4, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology.

4 Oct 2017

New non-invasive biomarker detects Alzheimer's disease before occurrence of first symptoms

Absence of a prefrontal activation during sensory gating of simple tones detects the Alzheimer's disease (AD) before the occurrence of the first symptoms. Sanja Josef Golubic Ph.D., physicists at the Department of Physics, Faculty of Science, University of Zagreb, reveals the high potential, absolutely non-invasive biomarker of AD pathology in a new study published in the journal Human Brain Mapping. Josef Golubic found a discrete, individual biomarker of AD with "ideal" properties.

3 Oct 2017

Losing sense of smell linked to dementia

Scientists have found that losing the sense of smell is an early sign that a person is at risk of development of dementia later in life. The study entitled “Olfactory Dysfunction Predicts Subsequent Dementia in Older US Adults,” was published in the latest issue of the Journal of the American Geriatrics Society.

2 Oct 2017

Impairing critical partnership between brain cells can lead to Alzheimer's disease

Researchers have discovered that impairing a critical partnership between brain cells can lead to neurodegeneration. The study published in Cell Metabolism reports a mechanism by which two types of brain cells, neurons and glia, normally support each other's functions.

30 Sep 2017

NIH awards $1.5 million grant to support education in Alzheimer's disease at RPI

We know Alzheimer's as a brutal disease that dismantles our loved ones and condemns them to death. But science and engineering researchers look inside the disease to identify early warning signs and develop the imaging techniques to see them, to unravel the biochemical puzzle that creates a toxic clump of misfolded proteins, and to develop and test new drugs and therapies that chip away at cognitive decline.

28 Sep 2017

Caffeine may not relieve movement symptoms for people with Parkinson's

Contrary to previous research, caffeine may not relieve movement symptoms for people with Parkinson's disease, according to a study published in the September 27, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology.

28 Sep 2017

FAU neuroscientist develops innovative program to prevent dementia

More than 5 million Americans today are affected by Alzheimer's disease (AD). If nothing is done to stop this upward trajectory, there will be more than 16 million people with AD in the United States and more than 60 million people with AD worldwide by 2050.

27 Sep 2017

Researchers reveal reason for olfactory dysfunction in initial stage of Alzheimer's disease

A research team led by DGIST Professor Moon Cheil at the Department of Brain and Cognitive Sciences has identified the reason why the patients with the early stage of Alzheimer's fail to smell.

27 Sep 2017

Study identifies novel molecular interactions that explain cognitive defects in Parkinson's disease

A study published in the journal Nature Neuroscience, from Nature publishing group, describes the identification of a novel molecular pathway that can constitute a therapeutic target for cognitive defects in Parkinson's disease.

25 Sep 2017

Multi-gene test found to be better at identifying older adults at risk for Alzheimer's

A new test that combines the effects of more than two dozen genetic variants, most associated by themselves with only a small risk of Alzheimer's disease, does a better job of predicting which cognitively normal older adults will go on to develop Alzheimer's dementia than testing only for the well-known genetic variant APOE E4, a scientific team led by researchers at UC San Francisco and UC San Diego has found.

22 Sep 2017

Personality changes do not appear before clinical onset of MCI or dementia

For years, scientists and physicians have been debating whether personality and behavior changes might appear prior to the onset of Alzheimer's disease and related dementias.

21 Sep 2017

New discovery about high-risk Alzheimer’s gene suggests potential therapeutic target

Nearly a quarter century ago, a genetic variant known as ApoE4 was identified as a major risk factor for Alzheimer's disease- one that increases a person's chances of developing the neurodegenerative disease by up to 12 times.

21 Sep 2017

Alzheimer's Disease News and Research

Further Reading

Scientists find new way to produce brain cells from single iPSC

Patients unaware of memory loss more likely to develop Alzheimer's disease, study shows

Scientists show how a trio of key molecules directs learning and memory

Alzheimer's gene can protect against and promote neurological damage

New $7.6 million NIA grant awarded to IU for Longitudinal Early-onset AD Study

Researchers propose LSD1 protein as central player in Alzheimer's and FTD

Powerful clot-busting drugs found safe for treating stroke patients with dementia

Study captures economic burden of frontotemporal degeneration in the United States

Women with high blood pressure in their 40s may more likely develop dementia later

New non-invasive biomarker detects Alzheimer's disease before occurrence of first symptoms

Losing sense of smell linked to dementia

Impairing critical partnership between brain cells can lead to Alzheimer's disease

NIH awards $1.5 million grant to support education in Alzheimer's disease at RPI

Caffeine may not relieve movement symptoms for people with Parkinson's

FAU neuroscientist develops innovative program to prevent dementia

Researchers reveal reason for olfactory dysfunction in initial stage of Alzheimer's disease

Study identifies novel molecular interactions that explain cognitive defects in Parkinson's disease

Multi-gene test found to be better at identifying older adults at risk for Alzheimer's

Personality changes do not appear before clinical onset of MCI or dementia

New discovery about high-risk Alzheimer’s gene suggests potential therapeutic target

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