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Engineering extracellular vesicles for potential treatment of type 1 diabetes

Within each of us lies an army of cells whose topmost duty is protecting against external pathogens and internal threats such as proliferating cancer cells.

14 Aug 2024

New trial explores BAFF CAR T-cell therapy for relapsed myeloma

University Hospitals (UH) Seidman Cancer Center hematologist-oncologist Leland Metheny, MD, is leading the trial.

14 Aug 2024

Study shows how segregated communities face challenges in filling OUD medications

Patients with a prescription for an opioid use disorder medication may have a tough time getting it filled if their pharmacy is in a community that's racially and economically segregated, according to a new study led by scientists at Oregon State University and Johns Hopkins University.

14 Aug 2024

KERI advances neuromodulation technology for appetite suppression in obesity treatment

The R&D on neuromodulation technology for the treatment and management of metabolic syndrome conducted by a team led by Dr. Ki-young Shin of Human Care Electro-Medical Device Research Center, Electro-Medical Equipment Research Division of KERI is underway smoothly.

14 Aug 2024

Ketogenic diet can boost efficacy of pancreatic cancer therapy

A study of fasting and the ketogenic diet reveals a new vulnerability of pancreatic tumors to an existing cancer drug.

14 Aug 2024

Liver stiffness becomes crucial indicator for post-treatment hepatitis C risk assessment

Hepatitis C can be cured in almost all cases with modern medication. However, if advanced liver damage is already present at the time of cure, there is still a residual risk of liver cancer and complications of portal hypertension, such as abdominal fluid, bleeding from the digestive tract and confusion.

14 Aug 2024

Menopause linked to increased risk of cognitive issues

With more than 24 million people globally living with dementia without a cure in sight, there is a lot of focus on ways to prevent and delay cognitive impairment. A new study suggests that severe menopause symptoms such as hot flashes and depression can negatively affect cognitive function in postmenopausal women. Results of the study are published online today in Menopause, the journal of The Menopause Society.

14 Aug 2024

Preterm babies show diverse cognitive and behavioral patterns

About thirteen million babies each year are born prematurely, with preterm birth linked to increases in risk for attention-deficit/hyperactivity disorder (ADHD), problems with social development, and lower grades.

13 Aug 2024

Nanoparticles offer new hope for treating red meat allergies linked to tick bites

Nanoparticles delivered intravenously in mice can block the allergic reactions to red meat caused by the bite of the lone star tick, new research led by the University of Michigan shows.

13 Aug 2024

Personalized treatment strategies based on calcification status in breast cancer

Mammographic calcifications, a common feature of breast cancer, have remained enigmatic in terms of their molecular underpinnings and clinical implications, particularly in the hormone receptor-positive, HER2-negative subtype.

13 Aug 2024

McGill discovery offers hope for targeted stem cell treatments

A new technique developed by McGill researchers for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential.

13 Aug 2024

New insights into the pharmacokinetics of remdesivir in treating SARS-CoV-2 in pregnant women

A new study provides important insights into the pharmacokinetics and safety of intravenous remdesivir in treating the SARS-CoV-2 coronavirus in pregnant women.

13 Aug 2024

Two studies uncover how immunotherapies work together to activate immune responses in melanoma

Two studies published in the latest issue of the journal Cell by University of Pittsburgh researchers uncover how immunotherapies targeting the immune checkpoints PD1 and LAG3 work together to activate immune responses.

13 Aug 2024

Scientists awarded $7.7 million grant to develop treatment for rare brain disorder

Children born with a damaged gene needed for healthy brain development, SYNGAP1, experience seizures, sensory processing disorders, difficulty speaking, intellectual disability, and autism-like behaviors.

13 Aug 2024

NCI awards $3.1 million to support new mental health model for cancer patients

Depression is common among people with likely incurable cancer – understandably so. But studies have shown that it can be treated, and if the goal is for individuals to be able to engage as much as possible with family, friends, hobbies or whatever gives them joy and purpose in whatever amount of time they have, then treating depression becomes imperative.

13 Aug 2024

Expanding horizons in Parkinson's disease care with non-pharmacological interventions

The field of non-pharmacological interventions for the treatment of individuals with Parkinson's disease (PD) is reaching maturity and has the potential to substantially improve patient care in the future.

13 Aug 2024

Mayo Clinic pioneers use of pulsed field ablation to treat atrial fibrillation

Cardiologists in Mayo Clinic's Heart Rhythm Clinic are using a new innovative energy source to safely and successfully treat a common type of heart arrhythmia.

13 Aug 2024

Early detection of cardiovascular diseases using advanced machine learning

How can diseases of the cardiovascular system be detected before symptoms appear? Researchers at Graz University of Technology (TU Graz) have found a way to track them down at an early stage.

13 Aug 2024

New genomic predictors of relapse in childhood B-cell acute lymphoblastic leukemia uncovered

Scientists from St. Jude Children's Research Hospital, Seattle Children's and the Children's Oncology Group (COG) have identified novel genetic variations that influence relapse risk in children with standard risk B-cell acute lymphoblastic leukemia (SR B-ALL), the most common childhood cancer.

12 Aug 2024

Novel exosome-based drug delivery system for synergistic cancer treatment

Ovarian cancer is one of the most common malignancies in women worldwide. Unlike breast cancer, ovarian cancer lacks early diagnostic markers and does not show noticeable symptoms until cancer metastases, leading to a low survival rate for ovarian cancer patients.

12 Aug 2024

Therapy News and Research

Engineering extracellular vesicles for potential treatment of type 1 diabetes

New trial explores BAFF CAR T-cell therapy for relapsed myeloma

Study shows how segregated communities face challenges in filling OUD medications

KERI advances neuromodulation technology for appetite suppression in obesity treatment

Ketogenic diet can boost efficacy of pancreatic cancer therapy

Liver stiffness becomes crucial indicator for post-treatment hepatitis C risk assessment

Menopause linked to increased risk of cognitive issues

Preterm babies show diverse cognitive and behavioral patterns

Nanoparticles offer new hope for treating red meat allergies linked to tick bites

Personalized treatment strategies based on calcification status in breast cancer

McGill discovery offers hope for targeted stem cell treatments

New insights into the pharmacokinetics of remdesivir in treating SARS-CoV-2 in pregnant women

Two studies uncover how immunotherapies work together to activate immune responses in melanoma

Scientists awarded $7.7 million grant to develop treatment for rare brain disorder

NCI awards $3.1 million to support new mental health model for cancer patients

Expanding horizons in Parkinson's disease care with non-pharmacological interventions

Mayo Clinic pioneers use of pulsed field ablation to treat atrial fibrillation

Early detection of cardiovascular diseases using advanced machine learning

New genomic predictors of relapse in childhood B-cell acute lymphoblastic leukemia uncovered

Novel exosome-based drug delivery system for synergistic cancer treatment

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