Immune System News and Research

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A potential way for overcoming immunotherapy resistance in patients with mucosal melanomas

The development of the anti-cancer immunotherapy drugs called immune checkpoint inhibitors has improved treatment for many cancer patients, but patients with mucosal melanomas - melanomas that occur not on the skin but in the mucous membranes in the head, neck, eyes, respiratory tract, and genitourinary region - are particularly resistant to immune checkpoint inhibitors for reasons researchers don't fully understand.

25 Apr 2022

New COVID-19 vaccine proven to be safe and effective in late-stage clinical testing

A COVID-19 vaccine developed at the University of Washington School of Medicine has proven safe and effective in late-stage clinical testing.

25 Apr 2022

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

As part of World Malaria Day 2022, we interview Karine Le Roch PH.D., about her latest research into how novel antimalarial therapeutic strategies could be on the horizon, after identifying two proteins that are critical to the survival of the malaria parasite, Plasmodium falciparum.

25 Apr 2022

Researchers identify cytokines that can help predict negative outcomes in COVID-19 patients

New research being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Lisbon, Portugal (23-26 April) has identified a panel of cytokines that can help predict which COVID-19 patients are at risk of serious illness and death.

23 Apr 2022

An abnormally suppressed immune system may be to blame in some cases of long COVID-19

A UCLA-led team of researchers studying the effect of the monoclonal antibody Leronlimab on long COVID-19 may have found a surprising clue to the baffling syndrome, one that contradicts their initial hypothesis.

22 Apr 2022

Antibodies that neutralize most sarbecoviruses, including SARS-CoV-2 variants

Researchers isolate three mAbs that broadly neutralized sarbecoviruses and carried out virological and structural studies of these mAbs.

21 Apr 2022

Interleukin-3 may contribute to alleviating asthma, research suggests

The messenger substance interleukin-3 produced by the body was previously considered to be pro-inflammatory in bronchial asthma.

21 Apr 2022

Study reveals how fungus blocks and bursts blood vessels in the brain

New research from the University of Sheffield has revealed how fungus blocks and bursts blood vessels in the brain, helping scientists better understand how meningitis starts.

21 Apr 2022

Researchers discover potential targets for treating perivascular fibrosis

Elevated blood pressure can cause a condition known as perivascular fibrosis, where the outside wall of a blood vessel thickens due to connective tissue build-up.

21 Apr 2022

Using CR2Crry to reduce the negative effects of brain hemorrhaging in premature infants

A little over 1% of babies born in the U.S. in 2020 fell under the category of very low birthweight, meaning they weighed less than 1,500 grams at birth or 3 pounds, 4 ounces. And considering that the Centers for Disease Control and Prevention says more than 3.5 million babies were born that year, almost 48,500 were considered to be at very low birthweight.

21 Apr 2022

Researchers test an experimental treatment for metastatic cancer

Researchers at the University of Oklahoma are testing an experimental treatment for metastatic cancer focusing on pancreatic cancer.

20 Apr 2022

Revolutionary mRNA vaccine technology: History, facts and the future

mRNA vaccine technology is a field full of promise – as well as unanswered questions – for communities living with the burden of the world’s most deadly infectious diseases.

20 Apr 2022

Newly discovered immune cell "soldier" could be a good target for immunotherapy

Despite the success of immunotherapy in helping many people with cancer, the majority of patients still do not respond to these treatments. There is need for continued research.

20 Apr 2022

Lab grown, self-renewing muscle stem cells can repair muscle tissue damage in mice

In proof-of-concept experiments, Johns Hopkins Medicine scientists say they have successfully cultivated human muscle stem cells capable of renewing themselves and repairing muscle tissue damage in mice, potentially advancing efforts to treat muscle injuries and muscle-wasting disorders in people.

20 Apr 2022

A new approach for treating multiple-drug resistant bacteria

Antibiotic-resistant hospital pathogens are not to be underestimated as a health risk. A research team has now introduced a new approach for treating multiple-drug resistant Staphylococcus in the journal Angewandte Chemie.

20 Apr 2022

CAR T-Cell Therapy: The Future of Cancer and HIV Treatment?

In this interview, News-Medical speaks to Professor Jun Huang about CAR T-cell therapy and its future as a potential treatment for cancer or HIV.

20 Apr 2022

Study reveals a complexity to how the body "regulates the regulators" of the immune system

Checkpoint inhibitors have become important tools in the cancer-fighting arsenal. By blocking proteins that normally restrain the immune response, these drugs can help the immune system destroy cancer cells.

20 Apr 2022

Research sheds new light on how the body's immune system deals with malaria

By analyzing samples from patients who have been treated for malaria in Sweden, researchers at Karolinska Institutet can now describe how the immune system acts to protect the body after a malaria infection.

19 Apr 2022

Scientists create a bioengineered 3D model that mimics the biology of two rare neuromuscular diseases

A scientific team supported by the National Institutes of Health has created a tiny, bioengineered 3-D model that mimics the biology of chronic inflammatory demyelinating polyneuropathy and multifocal motor neuropathy, a pair of rare, devastating neuromuscular diseases.

19 Apr 2022

Researchers discover a novel signaling pathway that defines interferon responses in blood cancers

Northwestern Medicine investigators have discovered a novel signaling pathway activated by interferons, a group of immune system proteins, that suppresses the anti-tumor response of interferons in patients with a particular type of blood cancer, according to findings published in Nature Communications.

19 Apr 2022

Immune System News and Research

A potential way for overcoming immunotherapy resistance in patients with mucosal melanomas

New COVID-19 vaccine proven to be safe and effective in late-stage clinical testing

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

Researchers identify cytokines that can help predict negative outcomes in COVID-19 patients

An abnormally suppressed immune system may be to blame in some cases of long COVID-19

Antibodies that neutralize most sarbecoviruses, including SARS-CoV-2 variants

Interleukin-3 may contribute to alleviating asthma, research suggests

Study reveals how fungus blocks and bursts blood vessels in the brain

Researchers discover potential targets for treating perivascular fibrosis

Using CR2Crry to reduce the negative effects of brain hemorrhaging in premature infants

Researchers test an experimental treatment for metastatic cancer

Revolutionary mRNA vaccine technology: History, facts and the future

Newly discovered immune cell "soldier" could be a good target for immunotherapy

Lab grown, self-renewing muscle stem cells can repair muscle tissue damage in mice

A new approach for treating multiple-drug resistant bacteria

CAR T-Cell Therapy: The Future of Cancer and HIV Treatment?

Study reveals a complexity to how the body "regulates the regulators" of the immune system

Research sheds new light on how the body's immune system deals with malaria

Scientists create a bioengineered 3D model that mimics the biology of two rare neuromuscular diseases

Researchers discover a novel signaling pathway that defines interferon responses in blood cancers

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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