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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Pinning down Pin1: Potential COVID-19 therapy

In a recent study scientists have demonstrated that Pin1 is one of the key cellular molecules necessary for SARS-CoV-2 propagation.

22 Sep 2021

The role of nanomaterials during the COVID-19 pandemic

A new review published in Rare Metals has focused on the applications of nanomaterials to fight the ongoing COVID-19 pandemic.

22 Sep 2021

SARS-CoV-2 genome signature leads to replicative advantage in presence of Remdesivir

A new study indicates that low-level resistance of SARS-CoV-2 to remdesivir is not widespread and dissimilar to other RNA viruses revealing evolutionary predictability of this pandemic virus.

22 Sep 2021

SARS-CoV-2 delta variant has higher viral RNA levels and increased infectivity, suggests study

The study found that the delta and epsilon variants exhibited significantly higher infectivity than alpha, with delta containing approximately six times as much infectious virus for the same amount of RNA.

22 Sep 2021

Discovery of genes opens the door to new treatments for obesity

Promising news in the effort to develop drugs to treat obesity: University of Virginia scientists have identified 14 genes that can cause and three that can prevent weight gain.

22 Sep 2021

Researchers identify distinctive biological markers for earlier detection of pregnancy risks

Researchers from Flinders University and the Robinson Research Institute at the University of Adelaide have identified distinctive biological markers that could improve the routine blood tests pregnant women already undergo and detect risks for pregnancy complications earlier than currently possible.

22 Sep 2021

Discovery points toward a new strategy for treating Parkinson’s disease

University of Utah Health scientists have identified a molecule that slows cells’ production of alpha-synuclein, a protein that forms toxic aggregates in the brains of people with Parkinson’s disease.

21 Sep 2021

Is the Pfizer-BioNTech COVID vaccine still effective after 6 months?

A team of researchers assessed the effectiveness of the Pfizer-BioNTech BNT162b2 mRNA COVID-19 vaccine.

21 Sep 2021

Study paves the way for development of novel delivery systems to suppress HIV

In a new study supported by the National Institutes of Health, researchers used exosomes, tiny nanoparticles capable of being taken up by cells, to deliver novel protein into the cells of mice infected with HIV. The protein attached to HIVs' genetic material and prevented it from replicating, resulting in reduced levels of HIV in the bone marrow, spleen, and brain.

21 Sep 2021

KU researcher wins $1.25 million award to investigate the vital role of sex hormones in tissue repair

Our ability to heal and regenerate new tissue after an injury has much to do with biological sex. For instance, following menopause, the loss of sex-hormone signaling in women can lead to degenerative diseases such as osteoporosis and osteoarthritis, where bone and cartilage degrade and become more delicate and brittle because of tissue loss.

21 Sep 2021

Scientists identify potential therapeutic targets to alleviate severe COVID-19 in aged patients

The scientists assessed epidemiological data from March to December 2020 from the CDC to investigate the prevalence of COVID-19 disease among different age groups.

21 Sep 2021

Dynamics of innate immune responses decide COVID-19 severity in genetically diverse mice

In a recently published article on the bioRxiv* preprint server, scientists from the USA and UK have described the significance of early inflammatory signaling pathways in determining the severity of coronavirus disease 2019 (COVID-19).

21 Sep 2021

Changes in fibrin clot structure contributes to thrombosis risk in severe COVID-19

Researchers from Europe recently demonstrated altered levels of factor XII (FXII) and its activation products in 2 independent cohorts of critically ill patients with COVID-19 compared to patients suffering from severe acute respiratory distress syndrome caused by the influenza virus (acute respiratory distress syndrome (ARDS)-influenza).

21 Sep 2021

Researchers reveal a mechanism of SHP2-mediated tumor immunosuppression

Colorectal cancer (CRC), a malignant tumor worldwide consists of microsatellite instability (MSI) and stable (MSS) phenotypes. Although SHP2 is a hopeful target for cancer therapy, its relationship with innate immunosuppression remains elusive. To address that, the authors of this article performed single-cell RNA sequencing to explore the role of SHP2 in all cell types of tumor microenvironment (TME) from murine MC38 xenografts.

21 Sep 2021

Differences in DNA methylation could accurately predict progression of liver disease

Findings of a national study led by the Translational Genomics Research Institute, an affiliate of City of Hope, identify potential biomarkers that might eventually be used to diagnose progressive stages of liver disease.

20 Sep 2021

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

In a recent study, researchers study the molecular aspects of SARS-CoV-2 host cell entry and inhibition of host-specific cellular mechanisms.

20 Sep 2021

Scientists simulate SARS-CoV-2 virion envelope using Martini 3

A new study proposes an integrative computational approach to model the structure of the SARS-CoV-2 envelope.

20 Sep 2021

Large scale 'proteogenomics' study could offer hope to patients with deadly pancreatic cancer

A large international collaboration led by researchers from the Johns Hopkins Kimmel Cancer Center has identified promising new targets for pancreatic cancer treatment and early diagnosis after examining various aspects of these tumors' genes and proteins.

20 Sep 2021

Hypertension in COVID-19-affected pregnancy linked to high SARS-CoV-2 load in placenta

A new study finds that hypertension following the viral infection is associated with high placental viral load in pregnant women with COVID-19.

20 Sep 2021

Atopic dermatitis may stem from poorly regulated sex hormones, study suggests

A study led by UT Southwestern dermatologists suggests that a common inflammatory skin condition may stem from poorly regulated sex hormones.

20 Sep 2021

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Further Reading

Pinning down Pin1: Potential COVID-19 therapy

The role of nanomaterials during the COVID-19 pandemic

SARS-CoV-2 genome signature leads to replicative advantage in presence of Remdesivir

SARS-CoV-2 delta variant has higher viral RNA levels and increased infectivity, suggests study

Discovery of genes opens the door to new treatments for obesity

Researchers identify distinctive biological markers for earlier detection of pregnancy risks

Discovery points toward a new strategy for treating Parkinson’s disease

Is the Pfizer-BioNTech COVID vaccine still effective after 6 months?

Study paves the way for development of novel delivery systems to suppress HIV

KU researcher wins $1.25 million award to investigate the vital role of sex hormones in tissue repair

Scientists identify potential therapeutic targets to alleviate severe COVID-19 in aged patients

Dynamics of innate immune responses decide COVID-19 severity in genetically diverse mice

Changes in fibrin clot structure contributes to thrombosis risk in severe COVID-19

Researchers reveal a mechanism of SHP2-mediated tumor immunosuppression

Differences in DNA methylation could accurately predict progression of liver disease

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

Scientists simulate SARS-CoV-2 virion envelope using Martini 3

Large scale 'proteogenomics' study could offer hope to patients with deadly pancreatic cancer

Hypertension in COVID-19-affected pregnancy linked to high SARS-CoV-2 load in placenta

Atopic dermatitis may stem from poorly regulated sex hormones, study suggests

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