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GlaxoSmithKline to cut some drug costs in emerging markets

GlaxoSmithKline (GSK) plans to decrease the prices of many of its leading medicines in emerging markets following the success of a pilot program in the Philippines, Andrew Witty, GSK's chief executive, said, Financial Times reports. Witty said the price cuts are part of an effort to diversify and expand globally.

15 Jun 2009

Reuters examines WHO efforts to fight H1N1 in developing countries

Reuters examines the WHO's battle against the H1N1 (swine flu) virus in "[d]eveloping countries, where medical care systems are weak and supplies of antivirals insufficient." In addition to "supplying countries with diagnostic kits, medicines and masks and gloves to protect health care workers and minimize the further spread of the new virus," the WHO is continuing to distribute doses of the antiviral Tamiflu, which has been "shown to be effective so far against H1N1," according to Reuters.

15 Jun 2009

Boston Globe examines the U.S. strategy towards global health

The Boston Globe examines the U.S. strategy towards global health aid. "President George W. Bush scored major advances in his administration's worldwide campaign against AIDS," and "[t]he Obama administration believes it can leverage Bush's successes into an assault against a much broader array of diseases that afflict poor countries," writes the Globe.

15 Jun 2009

Inflammation of microglia may not be associated with dementia in Alzheimer's disease

The idea that anti-inflammatory drugs might protect people struggling with dementia from Alzheimer's disease has received a blow with the online release of a study of human brain tissue in Acta Neuropathologica.

15 Jun 2009

Positron emission tomography scans may improve the accuracy of dementia diagnosis

A new study shows that the use of positron emission tomography (PET) scans may improve the accuracy of dementia diagnoses early in disease onset for more than one out of four patients. The results were presented at SNM's 56th Annual Meeting.

15 Jun 2009

Discovery of key molecular target in age-related macular degeneration

A team of researchers led by Dr. Jayakrishna Ambati at the University of Kentucky has discovered a biological marker for neovascular age-related macular degeneration (AMD), the leading cause of blindness in older adults.

15 Jun 2009

Research finds Tamiflu and Relenza relatively safe for use in pregnancy

With the H1N1 flu outbreak now elevated to pandemic level, a new article in CMAJ (Canadian Medical Association Journal) reports that oseltamivir (Tamiflu) and zanamivir (Relenza) are relatively safe drugs for use in pregnant and breast-feeding women.

15 Jun 2009

Discovery in dendritic cell signalling pathways pave way for new therapeutic targets

Scientists from A*STAR's Singapore Immunology Network (SIgN) and the University of Milano-Bicocca, Italy, have discovered another signaling pathway for the activation and apoptosis, or programmed cell death, of dendritic cells. This discovery was published in the advanced online publication of Nature on 15 Jun 2009.

15 Jun 2009

FDA releases fraudulent H1N1 flu virus product list

The U.S. Food and Drug Administration is enforcing the laws that protect consumers from illegal products marketed through the Internet that claim to diagnose, prevent, mitigate, treat or cure the 2009 H1N1 flu virus.

15 Jun 2009

Cancer immunotherapy can use small numbers of ‘stem-like’ immune cells to destroy large tumors in mice

A new approach to stimulating immune cells enhances their anticancer activity, resulting in a powerful anti-tumor response in mice, according to a study by researchers at the National Cancer Institute, a part of the National Institutes of Health. This work represents an important advance in the development of immunotherapy for cancer and appears online June 14, 2009 in Nature Medicine.

15 Jun 2009

A new way to tackle age-related macular degeneration

Researchers at the University of North Carolina at Chapel Hill School of Medicine in collaboration with lead investigators at the University of Kentucky have identified a new target for the diagnosis and treatment of age-related macular degeneration, the most common cause of blindness in older Americans.

15 Jun 2009

Discovery of key gene in deadly inflammatory breast cancer

Aggressive, deadly and often misdiagnosed, inflammatory breast cancer (IBC) is the most lethal form of primary breast cancer, often striking women in their prime and causing death within 18 to 24 months.

15 Jun 2009

Scientists launch Gene Expression Atlas

Today, researchers at the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) launch a new database, the Gene Expression Atlas, which allows scientists to search and compare gene expression data at unprecedented detail and scope. Observing how gene expression varies in different cell types, tissues and under disease conditions can help researchers understand gene function and to develop new drugs and therapies.

15 Jun 2009

Groundbreaking research may bring novel oral anti-diabetic drugs

Promise is held out for the development of novel oral drugs to control blood glucose levels in diabetes patients as the result of research by a Hebrew University of Jerusalem scientist.

15 Jun 2009

FSAs could end up on chopping block in hunt for health overhaul money

Around Christmas a few years ago, Princeton University economist Uwe Reinhardt was looking forward to a holiday dinner when his wife told him he shouldn't bother setting a place for himself. She had scheduled a colonoscopy for him for the next day.

13 Jun 2009

India to promote drugs in Africa after fake Chinese drugs 'made in India' seized

India launched a project to promote its $10.7 billion pharmaceutical industry in Africa after fake drugs labeled "Made in India," but with actual origins in China were seized on the continent, IANS/Hindu reports.

13 Jun 2009

International scientists' network to map drug-resistant malaria

PTI/Hindu reports on the Worldwide Antimalarial Resistance Network (WWARN) – an "international network of malaria scientists," which will be "established to map the emergence of resistance" to malaria drugs and "guide global efforts to control and eradicate the disease."

13 Jun 2009

Wall Street Journal examines program to spur vaccine development for developing world diseases

The Wall Street Journal examines a $1.5 billion program supported by Italy, the U.K., Canada, Russia, Norway and the Bill & Melinda Gates Foundation that hopes "to encourage pharmaceutical companies to develop vaccines for diseases common to poor countries," which is expected to be announced Friday "on the sidelines of a meeting of top finance officials from the Group of Eight major industrial powers."

13 Jun 2009

Diabetes drug exenatide promotes weight loss when added to diet and exercise

In combination with diet and exercise, the diabetes drug exenatide helped nondiabetic, obese individuals lose over three times more weight than those receiving a placebo, or dummy treatment, for 6 months.

13 Jun 2009

Waste disposal protein key to cancer tumor suppression in autophagy

"Taking out the trash" takes on a whole new meaning, as investigators at The Cancer Institute of New Jersey (CINJ) and Rutgers, The State University of New Jersey, have discovered that a waste disposal protein is the key to cancer tumor suppression in a process known as autophagy. CINJ is a Center of Excellence of UMDNJ-Robert Wood Johnson Medical School.

13 Jun 2009