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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Novel spike NTD mutations in SARS-CoV-2 Delta variant associated with increased viral loads and immune evasion

Researchers from the University of Southern California investigated mutations in the N-terminal and RBD domains of the spike protein.

20 Sep 2021

Medical staff with a history of allergy suffered adverse reactions to BNT162b2 COVID-19 vaccine

Scientists have addressed the gap in the research regarding the adverse reactions to the COVID-19 vaccine among individuals with allergies.

20 Sep 2021

First dose of COVID-19 mRNA vaccine (BNT162b2) reduced platelet polyP levels in young females

In a recent study, scientists have tested the hypothesis that indicates the role of polyP in the COVID-19 mRNA vaccine-induced immune responses.

20 Sep 2021

COVID-19 vaccine-related allergies are rare, typically mild and treatable, finds study

Allergic reactions to the new mRNA-based COVID-19 vaccines are rare, typically mild and treatable, and they should not deter people from becoming vaccinated, according to research from the Stanford University School of Medicine.

20 Sep 2021

A new synthetic multiantigen MVA vaccine COH04S1 effective against SARS-CoV-2

A new study utilized MVA to develop vaccine candidates that were subsequently evaluated in animal models of congenital cytomegalovirus disease.

19 Sep 2021

A variant analysis approach for SARS-CoV-2 in wastewater samples

A recent study proposes a simple and specific method for the enhanced detection of the SARS-CoV-2 VOCs in wastewater samples.

19 Sep 2021

Study shows efficacy of mRNA vaccines against SARS-CoV-2 in individuals with obesity

A new study evaluated the antibody response against SARS-CoV-2 between individuals who were affected by abdominal obesity (AO) and those who were not,

19 Sep 2021

A 100% French nasal vaccine against SARS-CoV-2 to move into the clinical phase in 2022

In contrast to intramuscular vaccines, only nasal vaccines are able to block the virus in the nose by inducing local immunity in the nasal mucosa, i.e. the portal of entry and multiplication of the virus.

18 Sep 2021

Scientists discover new cell type in human skin that contributes to inflammatory skin diseases

A team of international scientists and clinical experts have unraveled a new cell type in human skin that contributes to inflammatory skin diseases such as atopic dermatitis (AD) and psoriasis (PSO). Their study findings were published in the Journal of Experimental Medicine in September 2021.

17 Sep 2021

Pfizer vaccine induces strong immunity in elderly with prior COVID-19

A new study discusses the vaccination response in elderly who were vaccinated with one dose of the Pfizer vaccine 15 months after contracting COVID-19.

16 Sep 2021

New NIH-funded research to solve the male infertility and spermatogenesis puzzle

Male infertility is on the rise, with significant declines in sperm quantity and quality occurring across the human population worldwide in the past two decades.

16 Sep 2021

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

A new study describes a small molecule referred to as RG10 that may have potent antiviral activity against SARS-CoV-2 in human cells.

16 Sep 2021

Neutralizing monoclonal antibodies provide Fc receptor-independent SARS-CoV-2 protection in Hamsters

A study published in the journal mBio analyzes the capacity of the neutralizing MAb 2B04 to protect different antibody titers.

16 Sep 2021

Novel cell reprogramming offers a promising therapeutic strategy to slow down glioblastomas

Gliomas are the most common primary brain tumors in adults. Among them, high-grade glioblastomas (GBMs) are particularly known to be notoriously aggressive and invasive, which makes it challenging to treat them. The disease rapidly progresses to an advanced stage in a short span of time, and the survival of such patients is often dismal.

16 Sep 2021

Researchers aim to develop edible plant-based mRNA vaccines

The future of vaccines may look more like eating a salad than getting a shot in the arm. UC Riverside scientists are studying whether they can turn edible plants like lettuce into mRNA vaccine factories.

16 Sep 2021

UTHSC researcher receives funding to advance The Cancer Genome Atlas project

Neil Hayes, MD, MPH, director of the Center for Cancer Research at the University of Tennessee Health Science Center, is one of two principal investigators for a $1.8 million grant that extends the work of The Cancer Genome Atlas (TCGA), a groundbreaking multisite project to understand cancer at its molecular level through genome sequencing and extensive data analysis.

16 Sep 2021

Live oral SARS-CoV-2 vaccine provides partial protection in Rhesus Macaques

A new study describes the partial protection against respiratory infection with SARS-CoV-2 following gut inoculation with a live attenuated virus.

16 Sep 2021

Study provides the most detailed view of how ribosomes are assembled in human cells

All cells need ribosomes to make the proteins necessary for life. These multi-component molecular machines build complex proteins by stitching building blocks together according to instructions encoded in the cell's messenger RNAs.

16 Sep 2021

Study looks at drug resistance in BRAF-mutated gliomas

Looking to understand why some brain tumors with a specific mutation can start to reject drugs commonly used to treat them, CU Cancer Center member Jean Mulcahy Levy, MD, led researchers from institutions around the country - including several from the University of Colorado School of Medicine - to study samples of brain tumors before and after being treated with the drug.

16 Sep 2021

Evolved SARS-CoV-2 viruses gain higher infectivity and cause more rapid infection spread

Viruses accumulate mutations as they replicate in infected cells. Repeated replication can lead to viral strains that show attenuated virulence. Such strains may act as vaccines if the attenuated virus can produce immunity without serious disease.

16 Sep 2021

RNA News and Research

Further Reading

Novel spike NTD mutations in SARS-CoV-2 Delta variant associated with increased viral loads and immune evasion

Medical staff with a history of allergy suffered adverse reactions to BNT162b2 COVID-19 vaccine

First dose of COVID-19 mRNA vaccine (BNT162b2) reduced platelet polyP levels in young females

COVID-19 vaccine-related allergies are rare, typically mild and treatable, finds study

A new synthetic multiantigen MVA vaccine COH04S1 effective against SARS-CoV-2

A variant analysis approach for SARS-CoV-2 in wastewater samples

Study shows efficacy of mRNA vaccines against SARS-CoV-2 in individuals with obesity

A 100% French nasal vaccine against SARS-CoV-2 to move into the clinical phase in 2022

Scientists discover new cell type in human skin that contributes to inflammatory skin diseases

Pfizer vaccine induces strong immunity in elderly with prior COVID-19

New NIH-funded research to solve the male infertility and spermatogenesis puzzle

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

Neutralizing monoclonal antibodies provide Fc receptor-independent SARS-CoV-2 protection in Hamsters

Novel cell reprogramming offers a promising therapeutic strategy to slow down glioblastomas

Researchers aim to develop edible plant-based mRNA vaccines

UTHSC researcher receives funding to advance The Cancer Genome Atlas project

Live oral SARS-CoV-2 vaccine provides partial protection in Rhesus Macaques

Study provides the most detailed view of how ribosomes are assembled in human cells

Study looks at drug resistance in BRAF-mutated gliomas

Evolved SARS-CoV-2 viruses gain higher infectivity and cause more rapid infection spread

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