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Posterior left pericardiotomy linked to prevention of atrial fibrillation after cardiac surgery

A simple surgical technique during cardiac surgery was associated with a 56 percent reduction in the incidence of an irregular heart rhythm known as atrial fibrillation that can lead to stroke, with no added risks or side effects, according to a new study by Weill Cornell Medicine and NewYork-Presbyterian investigators.

15 Nov 2021

Anti-platelet drug class fails to extend survival in moderately ill COVID-19 patients

A drug class that blocks the activity of blood platelets and prevents clotting—P2Y12 inhibitors—failed to extend survival or lessen disease severity in patients with COVID-19 who were hospitalized but had a relatively moderate case, a new study finds.

15 Nov 2021

Penicillin can prevent progression of latent rheumatic heart disease in children

A regular, affordable antibiotic treatment significantly reduced the risk of underlying rheumatic heart disease progression in children and adolescents, according to a new study.

14 Nov 2021

Study provides a new target for therapeutic intervention in Parkinson's disease

In an unexpected discovery, Georgetown University Medical Center researchers have identified what appears to be a significant vascular defect in patients with moderately severe Parkinson's disease.

14 Nov 2021

Study finds benefits, drawbacks to two-step surgical approach for mitral and tricuspid valve regurgitation

Patients with mitral and tricuspid valve regurgitation, a condition sometimes called "leaky heart valves," appeared to do better after two years if they had a tricuspid valve repair at the time of mitral valve surgery, according to a study supported by the National Heart, Lung, and Blood Institute, a part of the National Institutes of Health.

14 Nov 2021

Study reveals how certain cells drive immunotherapy resistance in ovarian cancer mouse model

Immune checkpoint inhibitors are a type of cancer treatment that help the immune system's T cells recognize and attack tumors. But these immunotherapy drugs aren't effective against all cancers.

12 Nov 2021

Study assesses whether medicinal mushrooms and Chinese herbs can help treat COVID-19

A novel study is assessing whether medicinal mushrooms and Chinese herbs provide therapeutic benefit in treating acute COVID-19 infection.

12 Nov 2021

Regular blood tests can identify prostate cancer patients who are resistant to treatment

Regular blood tests before and during chemotherapy for prostate cancer can detect whether or not a patient is resistant or developing resistance to treatment with docetaxel, according to research presented at the NCRI Festival.

11 Nov 2021

Bariatric surgery lowers risk of liver disease, heart complications in patients with fatty liver disease

A Cleveland Clinic study shows that patients with obesity and advanced fatty liver disease who had bariatric weight loss surgery significantly lowered their future risk of liver disease complications and serious cardiovascular disease compared with patients who did not have surgery.

11 Nov 2021

Analysis of immunodeficient patients granted REGEN-COV under compassionate use COVID-19 program

A team of scientists describe the safety and response to REGEN-COV® for COVID-19 patients with immunodeficiency-associated antibody disorders.

11 Nov 2021

Combination treatment improves overall survival for melanoma patients with brain metastases

Combination treatment with immune checkpoint inhibitors nivolumab and ipilimumab demonstrates overall survival for patients with melanoma that has spread to the brain, according to Phase II study results published today in The Lancet Oncology by researchers from The University of Texas MD Anderson Cancer Center.

11 Nov 2021

Drug combination highly effective in children with standard- and high-risk acute promyelocytic leukemia

A clinical trial has found that the combination of all-trans retinoic acid, which is a metabolite of vitamin A, and arsenic trioxide is highly effective in children with standard- and high-risk acute promyelocytic leukemia, or APL.

11 Nov 2021

Exercise reduces upper limb disability after breast cancer surgery

Women who exercise shortly after having non-reconstructive breast cancer surgery appear to regain better shoulder and arm mobility and experience less pain than those who receive standard care, suggests a study published by The BMJ today.

11 Nov 2021

Immunity following COVID-19 vaccination and natural infection in India

The researchers evaluated immune response markers in a cross-section of people from the Indian state of West Bengal, including those vaccinated with either Covishield or Covaxin, the unvaccinated cohort, and the naturally infected.

11 Nov 2021

Effectiveness of sotrovimab demonstrated in patients with mild to moderate COVID-19

In an attempt to study the safety and effectiveness of sotrovimab in more vulnerable patients suffering from mild to moderate symptoms of COVID-19, a multinational team of researchers conducted the COVID-19 Monoclonal antibody Efficacy Trial-Intent to Care Early (COMET-ICE) trial.

11 Nov 2021

Study reveals ways to debunk highly prevalent health misinformation

The current pandemic shows how quickly health misinformation can spread. However, there are tools to debunk misinformation as demonstrated by a new study on health communication strategies from Karolinska Institutet in Sweden, published in the journal BMJ Global Health.

10 Nov 2021

Immune checkpoint inhibitor therapy results in longer treatment-free survival for patients with advanced renal cell carcinoma

Patients with advanced renal cell carcinoma who received the checkpoint inhibitor combination nivolumab (Opdivo) plus ipilimumab (Yervoy) experienced longer treatment-free survival (TFS) over a 42-month period than patients who received the targeted therapy sunitinib (Sutent), regardless of the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) risk group, according to new analysis of the CheckMate-214 clinical trial.

10 Nov 2021

ACTG announces launch of clinical trial evaluating a three-month TB treatment

The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, today announced the launch of A5362 (CLO-FAST), a clinical trial studying a three-month clofazimine- and high-dose rifapentine-containing treatment regimen for people with drug-susceptible tuberculosis (TB).

10 Nov 2021

Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

Researchers at Yale School of Medicine have discovered that an RNA molecule that stimulates the body's early antiviral defense system can protect mice from a range of emerging SARS-CoV-2 variants.

10 Nov 2021

New method of stem cell transplantation may eliminate the need for radiation or chemotherapy

Studying mice, researchers at Washington University School of Medicine in St. Louis have developed a method of stem cell transplantation that does not require radiation or chemotherapy.

10 Nov 2021

Clinical Trial News and Research

Posterior left pericardiotomy linked to prevention of atrial fibrillation after cardiac surgery

Anti-platelet drug class fails to extend survival in moderately ill COVID-19 patients

Penicillin can prevent progression of latent rheumatic heart disease in children

Study provides a new target for therapeutic intervention in Parkinson's disease

Study finds benefits, drawbacks to two-step surgical approach for mitral and tricuspid valve regurgitation

Study reveals how certain cells drive immunotherapy resistance in ovarian cancer mouse model

Study assesses whether medicinal mushrooms and Chinese herbs can help treat COVID-19

Regular blood tests can identify prostate cancer patients who are resistant to treatment

Bariatric surgery lowers risk of liver disease, heart complications in patients with fatty liver disease

Analysis of immunodeficient patients granted REGEN-COV under compassionate use COVID-19 program

Combination treatment improves overall survival for melanoma patients with brain metastases

Drug combination highly effective in children with standard- and high-risk acute promyelocytic leukemia

Exercise reduces upper limb disability after breast cancer surgery

Immunity following COVID-19 vaccination and natural infection in India

Effectiveness of sotrovimab demonstrated in patients with mild to moderate COVID-19

Study reveals ways to debunk highly prevalent health misinformation

Immune checkpoint inhibitor therapy results in longer treatment-free survival for patients with advanced renal cell carcinoma

ACTG announces launch of clinical trial evaluating a three-month TB treatment

Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

New method of stem cell transplantation may eliminate the need for radiation or chemotherapy

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