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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Scientists develop a novel and potent SARS-CoV-2 RBD-homodimer vaccine

A recent report published in the journal Cell Discovery has described the immunogenicity and protective efficacy of a novel coronavirus disease 2019 (COVID-19) subunit vaccine candidate. The vaccine induces robust immune responses in rodents and non-human primates and protects the animals against severe disease.

12 Sep 2021

Researchers discover transposon-encoded RNA-guided nucleases with potential for genome editing

Researchers seeking to understand the origins of CRISPR-Cas9 systems have uncovered a class of transposon-encoded RNA-guided nucleases, which they dubbed "OMEGA," that could be harnessed for genome editing in human cells.

12 Sep 2021

Drugs that mimic effects of cigarette smoke could become a potential tool to fight COVID-19

Researchers have identified two drugs that mimic the effect of chemicals in cigarette smoke to bind to a receptor in mammalian cells that inhibits production of ACE2 proteins, a process that appears to reduce the ability of the SARS-CoV-2 virus to enter the cell.

12 Sep 2021

UGA research offers hope for a viable therapeutic to combat COVID-19

As COVID-19 cases continue to skyrocket across the U.S. and the world, few options are available for treating patients infected with the SARS-CoV-2.

11 Sep 2021

NIH researchers develop a detailed cellular map of chronic MS lesions

Chronic lesions with inflamed rims, or "smoldering" plaques, in the brains of people with multiple sclerosis (MS) have been linked to more aggressive and disabling forms of the disease.

10 Sep 2021

Nanoparticles-assisted delivery of antiviral-siRNA for treatment of COVID-19

A review aimed to determine the potential of siRNA as a potential COVID-19 treatment by reviewing the currently available literature.

10 Sep 2021

Breastfeeding women and their babies: the outcomes after mRNA COVID-19 vaccination

Scientists evaluated the effect of vaccination in breastfeeding women and its possible effects in infants in a study involving 180 fully vaccinated, breastfeeding women.

10 Sep 2021

New gene-delivering workhorse could make gene therapy safer, more effective for muscle diseases

Genetic muscle diseases lead to progressive muscle wasting and often early death, with few treatment options and no cure.

9 Sep 2021

The role of nanobodies in capturing and containing SARS-CoV-2

Scientists have repurposed the Nb Ty1 for the detection and neutralization of SARS-CoV-2.

8 Sep 2021

Research reveals a new role for platelets in COVID-19 blood vessel damage

Abnormal crosstalk between blood platelets and cells lining blood vessels is one cause of deadly organ damage in patients with severe COVID-19, a new study finds.

8 Sep 2021

Study finds no serious side effects of mRNA COVID-19 vaccines in lactating women, breastfed infants

In December 2020, two novel messenger RNA (mRNA) vaccines for SARS-CoV-2 received emergency use authorization from the U.S. Food and Drug Administration; however, the early trials excluded lactating women, leading to questions about their safety in this specific population.

8 Sep 2021

Understanding platelets in COVID-19 may help identify diagnostic markers and treatments

Researchers in the United States and Japan have provided novel insights into the pathologic mechanisms underlying coronavirus disease 2019 (COVID-19) that may aid the identification of potential diagnostic biomarkers and treatment targets.

8 Sep 2021

Potential pancoronavirus fusion inhibitors that are effective against SARS-CoV-2 variants

A new study successfully identifies a series of inhibitors that possesses pancoronavirus activity against SARS-CoV, SARS-CoV-2, and MERS-CoV.

7 Sep 2021

Highly neutralizing human convalescent plasma reduces lung inflammation in SARS-CoV-2-infected macaques

A new study reignites the debate regarding the therapeutic utility of convalescent plasma in treating others with the COVID-19.

7 Sep 2021

Research reveals a previously unknown role for a key transcription regulator linked to cancer

CTCF is a transcription factor that has been a research target due to its role in regulating a critical oncogene called MYC.

7 Sep 2021

High COVID-19 vaccine effectiveness in Israeli HCP

A study aimed to evaluate the VE against SARS-CoV-2 infection by carrying out a prospective cohort study that included healthcare personnel (HCP) in six hospitals in Israel.

7 Sep 2021

Multiplexed electrochemical sensor platform enables simultaneous detection of SARS-CoV-2 RNA and host antibodies

Scientists from the UK and USA have developed an antifouling nanocomposite-coated multiplexed electrochemical sensor platform that can simultaneously detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA and virus-specific antibodies. The platform has shown 100% accuracy in detecting viral RNA and IgG-specific anti-SARS-CoV-2 antibodies. The study is currently available on the medRxiv* preprint server.

6 Sep 2021

RNA News and Research

Further Reading

Scientists develop a novel and potent SARS-CoV-2 RBD-homodimer vaccine

Researchers discover transposon-encoded RNA-guided nucleases with potential for genome editing

Drugs that mimic effects of cigarette smoke could become a potential tool to fight COVID-19

UGA research offers hope for a viable therapeutic to combat COVID-19

NIH researchers develop a detailed cellular map of chronic MS lesions

Nanoparticles-assisted delivery of antiviral-siRNA for treatment of COVID-19

Breastfeeding women and their babies: the outcomes after mRNA COVID-19 vaccination

New gene-delivering workhorse could make gene therapy safer, more effective for muscle diseases

The role of nanobodies in capturing and containing SARS-CoV-2

Research reveals a new role for platelets in COVID-19 blood vessel damage

Study finds no serious side effects of mRNA COVID-19 vaccines in lactating women, breastfed infants

Understanding platelets in COVID-19 may help identify diagnostic markers and treatments

Potential pancoronavirus fusion inhibitors that are effective against SARS-CoV-2 variants

Highly neutralizing human convalescent plasma reduces lung inflammation in SARS-CoV-2-infected macaques

Research reveals a previously unknown role for a key transcription regulator linked to cancer

High COVID-19 vaccine effectiveness in Israeli HCP

Multiplexed electrochemical sensor platform enables simultaneous detection of SARS-CoV-2 RNA and host antibodies

Simple, non-invasive tool obviates unnecessary surgery in patients with colorectal cancer

Reduction in infectious SARS-CoV-2 shedding in vaccine breakthrough infections

Characterization of SARS-CoV-2 viral trajectory

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