Angina News and Research

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Angina is chest pain or discomfort that occurs when an area of your heart muscle doesn't get enough oxygen-rich blood. Angina may feel like pressure or squeezing in your chest. The pain also may occur in your shoulders, arms, neck, jaw, or back. It can feel like indigestion.

Preventive PCI for patients with ST elevation myocardial infarction results in better outcomes

Heart attack patients with ST elevation who undergo a preventive procedure to unblock additional coronary arteries have significantly better outcomes than those whose treatment is confined to the culprit blockage only, according to the results of the Preventive Angioplasty in Myocardial Infarction (PRAMI) Trial

5 Sep 2013

Golgi apparatus: New target for treatment of acute cerebral infarction

Expression of soluble CD40L has been shown to increase sig-nificantly in conditions such as stroke, myocardial infarction, unstable angina, high cholesterol, or other cardiovascular events. 95% of the circulating CD40L exists in activated platelets.

5 Sep 2013

Sanofi, POZEN ink license agreement to commercialize PA8140 and PA32540 tablets in US

Sanofi US and POZEN Inc. announced the signing of an exclusive license agreement for the commercialization of POZEN's proprietary, investigational, coordinated-delivery tablets combining immediate-release omeprazole, a proton pump inhibitor, and enteric-coated aspirin in a single tablet ("PA"), PA8140 and PA32540.

5 Sep 2013

Study: Children born to obese mothers are more likely to die early as adults

Children born to obese mothers are more likely to die early as adults than those whose mothers were a normal weight, a study has found.

16 Aug 2013

Boehringer Ingelheim, Lilly initiate linagliptin clinical trial in adults with Type 2 Diabetes

Boehringer Ingelheim and Eli Lilly and Company today announced enrollment of the first patient into a cardiovascular and renal outcomes trial for linagliptin (Trajenta).

1 Aug 2013

AstraZeneca, FibroGen partner to develop, commercialize anemia drug candidate FG-4592

AstraZeneca and FibroGen today announced that they have entered into a strategic collaboration to develop and commercialize FG-4592, a first-in-class oral compound in late stage development for the treatment of anemia associated with chronic kidney disease and end-stage renal disease.

31 Jul 2013

Many women die due to Cad, yet less likely to receive preventive recommendations

Despite coronary artery disease (CAD) killing at least as many women as men each year, women are still today less likely to receive preventive recommendations, such as lipid-lowering therapy, aspirin, and lifestyle advice, than are men at a similar risk level.

29 Jul 2013

Study: Daily dietary supplementation with blend of omega fatty acids improves severe dry eye

Study findings published online, ahead of print, in Cornea show that daily dietary supplementation with a unique combination of omega fatty acids (GLA, EPA and DHA) for six months is effective in improving ocular irritation symptoms and halting the progression of inflammation that characterizes moderate to severe dry eye.

25 Jul 2013

Report reveals off-pump CABG surgery failed to show any improvement in short-term mortality

In a Special Report in the current issue of Circulation, Boston Medical Center cardiothoracic surgeon Harold Lazar, MD, has found that off-pump coronary artery bypass graft (OPCAB) surgery has failed to show any significant improvement in short-term morbidity or mortality as compared to the traditional on-pump coronary artery bypass graft (CABG) surgery.

23 Jul 2013

Tianyin Pharmaceutical provides further updates on Gingko Mihuan Oral Liquid

Tianyin Pharmaceutical Co., Inc., a pharmaceutical company that specializes in patented biopharmaceutical, modernized traditional Chinese medicine, branded generics and active pharmaceutical ingredients today provided further updates on the business development of its flagship product: Gingko Mihuan Oral Liquid with the SFDA approval number: H20013079.

19 Jul 2013

Dual antiplatelet therapy improves outcomes in patients undergoing coronary stenting

Emmanouil S. Brilakis, M.D., Ph.D., of the VA North Texas Health Care System and University of Texas Southwestern Medical Center at Dallas, and colleagues conducted a review of medical literature regarding optimal medical therapy after percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries).

10 Jul 2013

Low vitamin D blood levels associated with greater risk of heart disease varies by race, ethnicity

Low vitamin D blood levels are linked to greater risk of heart disease in whites and Chinese, but not in blacks and Hispanics, according to a study appearing this week in JAMA, a journal published by the American Medical Association.

10 Jul 2013

Janssen receives complete response letter from FDA for XARELTO sNDA

Janssen Research & Development, LLC today announced the U.S. Food and Drug Administration has issued a complete response letter for the supplemental New Drug Application for XARELTO (rivaroxaban) to reduce the risk of stent thrombosis in patients with acute coronary syndrome.

28 Jun 2013

Men with haplogroup I of Y chromosome have 50% greater risk of developing heart disease

University of Leicester scientists have discovered a potential genetic contributor to the increased risk of heart disease among men.

18 Jun 2013

Amedra Pharmaceuticals re-launches single-dose epinephrine auto-injector, Adrenaclick

Amedra Pharmaceuticals LLC has announced re-launch of Adrenaclick®, a single-dose epinephrine auto-injector, for the emergency treatment of life threatening allergic reactions in people who are at risk for or have a history of anaphylaxis. Adrenaclick® will be available as a two-pack carton in both 0.15 mg and 0.30 mg strengths.

15 Jun 2013

Lineage Therapeutics announces US launch of generic epinephrine auto-injector

Lineage Therapeutics Inc. has announced the US launch of its generic epinephrine injection, USP auto-injector, the authorized generic of Adrenaclick by Amedra Pharmaceuticals LLC, for the emergency treatment of life-threatening allergic reactions in people who are at risk for or have a history of anaphylaxis.

15 Jun 2013

Routine use of FFR at diagnostic coronary angiography changes management in 26% of patients

Routinely measuring fractional flow reserve using pressure wire assessment during coronary angiography for diagnosis of chest pain leads to significant changes in the management of one in four patients, according to results from a study reported at EuroPCR 2013.

27 May 2013

$Study: Long-term mortality in patients with refractory angina is surprisingly low$

Study: Long-term mortality in patients with refractory angina is surprisingly low

Death rates associated with patients with refractory angina, or chronic chest pain, are lower than previously considered; therefore, physicians should focus on relieving the chest pain symptoms and improving the quality of life in these patients according to an article published online this week in the European Heart Journal.

16 May 2013

$COSIRA trial: Enrollment complete for assessing Neovasc Reducer in refractory angina patients$

COSIRA trial: Enrollment complete for assessing Neovasc Reducer in refractory angina patients

Neovasc Inc., today announced the completion of patient enrollment in its COSIRA trial designed to further assess the efficacy and safety of the Neovasc Reducer, a novel percutaneous device for the treatment of refractory angina.

13 May 2013

New protocol for reducing the use of SPECT SPI is found to be diagnostically safe

A new stress test protocol that investigates reducing the use of perfusion imaging in low risk patients undergoing SPECT myocardial perfusion imaging for possible angina symptoms was found to be diagnostically safe, revealed a US retrospective analysis.

6 May 2013

Angina News and Research

Further Reading

Preventive PCI for patients with ST elevation myocardial infarction results in better outcomes

Golgi apparatus: New target for treatment of acute cerebral infarction

Sanofi, POZEN ink license agreement to commercialize PA8140 and PA32540 tablets in US

Study: Children born to obese mothers are more likely to die early as adults

Boehringer Ingelheim, Lilly initiate linagliptin clinical trial in adults with Type 2 Diabetes

AstraZeneca, FibroGen partner to develop, commercialize anemia drug candidate FG-4592

Many women die due to Cad, yet less likely to receive preventive recommendations

Study: Daily dietary supplementation with blend of omega fatty acids improves severe dry eye

Report reveals off-pump CABG surgery failed to show any improvement in short-term mortality

Tianyin Pharmaceutical provides further updates on Gingko Mihuan Oral Liquid

Dual antiplatelet therapy improves outcomes in patients undergoing coronary stenting

Low vitamin D blood levels associated with greater risk of heart disease varies by race, ethnicity

Janssen receives complete response letter from FDA for XARELTO sNDA

Men with haplogroup I of Y chromosome have 50% greater risk of developing heart disease

Amedra Pharmaceuticals re-launches single-dose epinephrine auto-injector, Adrenaclick

Lineage Therapeutics announces US launch of generic epinephrine auto-injector

Routine use of FFR at diagnostic coronary angiography changes management in 26% of patients

Study: Long-term mortality in patients with refractory angina is surprisingly low

COSIRA trial: Enrollment complete for assessing Neovasc Reducer in refractory angina patients

New protocol for reducing the use of SPECT SPI is found to be diagnostically safe

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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