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Blocking ZFP36L2 protein may disrupt colorectal cancer metastatic growth

Digestion is hard on the cells that line the human gut, and they are constantly being shed and replaced. This renewal is driven by a population of tireless stem cells.

5 Aug 2026

Patient-derived tumor models strengthen precision oncology research

A research project funded by the National Institutes of Health (NIH), with collaborators around the country and the world, has generated one of the most extensive and diverse collections of patient-derived tumor models.

5 Aug 2026

Expanded DepMap reveals new cancer vulnerabilities through 3D tumor models

For nearly a decade, the Cancer Dependency Map, or DepMap, at the Broad Institute has helped scientists uncover new cancer dependencies - the genetic changes some cancers need to thrive that can potentially be targeted by new cancer drugs.

5 Aug 2026

New insights highlight Megalin's expanding role in disease management

A comprehensive new analysis is shining a spotlight on Megalin, a powerful and highly versatile receptor that plays a central role in maintaining cellular balance, organ function, and overall human health.

5 Aug 2026

Targeting lactylation could overcome cancer therapy resistance challenges

A growing body of scientific insight is transforming how cancer treatment resistance is understood, highlighting a powerful cellular process known as lactylation as a central driver of disease progression and therapeutic failure.

5 Aug 2026

HMGCR emerges as a promising target for precision cancer therapies

A growing body of evidence is reshaping how scientists and clinicians understand the role of cancer metabolism, placing the enzyme HMGCR at the center of a rapidly evolving therapeutic landscape.

5 Aug 2026

Discovery may help develop new treatments for immunosuppressed skin cancer patients

Researchers at The University of Texas MD Anderson Cancer Center have discovered that immunosuppressed patients with non-melanoma skin cancer are not missing the key cancer-fighting immune cells found in immunocompetent patients, but those cells – known as macrophages – have lost the ability to communicate effectively.

5 Aug 2026

Inherited Neandertal gene variant increases muscle mass in modern humans

Neandertals were generally more strongly built than most people living today. Their bones show signs of large muscles, and they had characteristic features such as prominent brow ridges and relatively short tooth roots.

5 Aug 2026

Cellular senescence drives progression of spinal disc degeneration and pain

A growing body of scientific insight is drawing attention to cellular senescence as a central force in the progression of intervertebral disc degeneration (IDD), a leading contributor to chronic low back pain worldwide.

5 Aug 2026

KCNE gene family emerges as a promising target for future precision medicine

A growing understanding of the KCNE gene family is reshaping how scientists view the regulation of electrical signaling across the human body, highlighting its essential role in maintaining normal physiological function and its connection to a wide range of diseases.

5 Aug 2026

Targeted dendritic cell vaccines emerge as a major step forward in cancer immunotherapy

A major step forward in cancer immunotherapy is emerging through the growing development of dendritic cell vaccines, a highly targeted approach designed to harness the body's own immune system to fight tumors.

5 Aug 2026

Review highlights the importance of miR-23b in shaping cancer development and progression

A new review highlights the growing importance of miR-23b, a small but powerful regulator of gene expression, in shaping the development and progression of a wide range of cancers.

5 Aug 2026

Versatile receptor protein plays critical role in regulating tissue repair

A comprehensive new review highlights the expanding importance of Lgr6, a member of the G protein-coupled receptor family, as a critical regulator of tissue homeostasis, injury repair, and disease development across multiple organ systems.

5 Aug 2026

Specialized selenoproteins play critical role in regulating cellular health

A new review highlights the remarkable importance of selenoproteins, a specialized group of molecules that, despite their small size, play a decisive role in shaping cellular fate and maintaining biological balance.

5 Aug 2026

Obscure X chromosome protein emerges as key driver in several cancers

A little-known protein encoded on the X chromosome is attracting growing attention for its potential role in cancer development and treatment.

5 Aug 2026

Intertwined cellular processes reshape understanding of diabetes

A deeper understanding of how key cellular processes interact is reshaping perspectives on diabetes and its wide-ranging complications.

5 Aug 2026

Scientists unmask immune cells that supercharge the fight against cancer

A little‑known group of hard-to-find immune cells could help transform cancer treatment, scientists at the University of Manchester’s Cancer Research UK Manchester Institute, have found.

5 Aug 2026

New metric detects early Alzheimer’s changes in brain's white matter

Alzheimer's disease has traditionally been studied as a condition that primarily affects the brain's gray matter, where neuronal cell bodies are located and some of the disease's most characteristic lesions accumulate.

5 Aug 2026

New portable blood testing device allows remote health monitoring

A new portable blood testing device could allow patient health to be monitored at home through an app.

5 Aug 2026

Cancer cells exploit liver fat to evade immune system destruction

Liver metastases are among the most common and deadly forms of cancer spread. Now, researchers at VIB and KU Leuven, with international collaborators, have discovered how cancer cells exploit a fatty acid abundant in the liver to evade destruction by the immune system.

5 Aug 2026