Cell Death News and Research

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Biomass smoke compounds linked to lung damage and respiratory diseases

Biomass burning-whether from wildfires, wood stoves or agricultural fires-sends massive amounts of tiny particles and chemicals into the air.

27 Feb 2025

Single-cell analysis reveals key chondrocyte subpopulations in osteoarthritis

Chondrocytes are specialized cells that are essential for cartilage maintenance and repair, and their dysfunction is central to the development of joint diseases like osteoarthritis (OA).

26 Feb 2025

LJI scientists discover a potential new target for treating Parkinson's disease

Scientists at La Jolla Institute for Immunology (LJI) have found a potential new target for treating Parkinson's disease.

25 Feb 2025

New mechanism uncovered to combat therapy-resistant cancer cells

One particular challenge in the treatment of cancer is therapy resistance. An international research team has now discovered a mechanism that opens up new treatment strategies for tumors in which conventional chemotherapeutic agents have reached their limits.

25 Feb 2025

New photosensitizer shows promise in treating colorectal cancer

Colorectal cancer (CRC) is a highly malignant disease that readily metastasizes to vital organs. Many strategies have been employed for clinical CRC therapy.

22 Feb 2025

Exploring the dual role of LKB1 in tumor suppression and promotion

Mutations in serine-threonine kinase 11 (STK11) and liver kinase B1 (LKB1) are associated with disease progression in Peutz-Jeghers syndrome (PJS), which can progress to cancer.

22 Feb 2025

Targeted mRNA therapy shows promise for healing damaged lungs

A combination of mRNA and a new lipid nanoparticle could help heal damaged lungs, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

21 Feb 2025

Exploring how 25-hydroxycholesterol triggers ferroptosis in glial cells

Oxysterols are a class of molecules derived from cholesterol via oxidation or as byproducts of cholesterol synthesis.

20 Feb 2025

New mRNA technique targets disease cells while sparing healthy ones

Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients with abnormal protein synthesis are treated to produce a healthy protein.

19 Feb 2025

Strengthening the gut barrier may halt Crohn’s disease progression

Researchers at the University of Gothenburg, Sweden, have uncovered a critical mechanism that may pave the way for innovative treatments for Crohn's disease.

18 Feb 2025

Sweat fails to match blood in tracking inflammation after heart attacks

Researchers found that while sweat biomarkers remain stable, plasma biomarkers show significant inflammatory changes after a heart attack, highlighting the limitations of sweat analysis for tracking recovery.

17 Feb 2025

Stanford researchers identify key variants linked to inherited cancer risk

Thousands of single changes in the nucleotides that make up the human genome have been associated with an increased risk of developing cancer.

17 Feb 2025

Study reveals key mechanisms behind cancer cells adapting to extra chromosomes

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

13 Feb 2025

UCLA study reveals key role of mismatch repair genes in Huntington’s disease

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies.

11 Feb 2025