Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

New recommendations aim to identify children with familial hypercholesterolemia

The Family Heart Foundation, a leading research and advocacy organization, announced the online publication of recommendations from a multidisciplinary panel in the Journal of Pediatrics to promote the early identification of children living with familial hypercholesterolemia (FH).

23 Sep 2025

Orforglipron pill improves heart and metabolic risk factors in trial

Patients taking an experimental oral GLP-1 drug lost significant weight and improved their heart and metabolic risk factors in a large, international, phase 3 clinical trial led by investigators at Weill Cornell Medicine, McMaster University, York University and other institutions.

22 Sep 2025

Scientists use blood chemistry to predict disease years before it strikes

Researchers built the largest plasma metabolome-phenome atlas using 274,241 UK Biobank participants, linking over 73,000 metabolite-trait and 52,000 metabolite-disease associations. The study shows metabolic risk scores can predict diseases years before diagnosis, with strong accuracy for diabetes and kidney complications.

22 Sep 2025

Coffee protects the liver by blocking inflammation and scarring, review finds

A new review in Biochemical Pharmacology synthesizes decades of research showing consistent links between regular coffee consumption and reduced risk of liver disease, including cirrhosis and liver cancer. Coffee’s bioactive compounds act on antioxidant, anti-inflammatory, antifibrotic, and metabolic pathways to slow liver damage progression.

21 Sep 2025

Glucose-fructose mix found in sugary drinks fuels colorectal cancer metastasis

A new study from researchers at The University of Texas MD Anderson Cancer Center shows that the glucose-fructose mix found in sugary drinks directly fuels metastasis in preclinical models of advanced colorectal cancer.

19 Sep 2025

Replacing red meat with legumes improves heart health and supports weight management

A University of Helsinki study found that partially replacing red and processed meat with pea- and faba bean–based foods resulted in reduced total and 'bad' LDL cholesterol levels in men, along with weight loss.

19 Sep 2025

Can eating style affect how well GLP-1 drugs control diabetes and weight?

Research indicates that external eating behavior is a key predictor of weight loss in type 2 diabetes patients receiving GLP-1 receptor agonists.

19 Sep 2025

Study reveals how a little-understood protein contributes to blood vessel leakage

A new study from the University of Oklahoma reveals how a little-understood protein, CD82, contributes to blood vessel leakage, a process that initiates inflammation but becomes dangerous when it occurs during severe inflammatory diseases such as sepsis, acute respiratory distress syndrome and COVID-19.

18 Sep 2025

Oral GLP-1 drug orforglipron achieves significant weight loss in global trial

Patients taking an experimental oral GLP-1 drug lost significant weight and improved their heart and metabolic risk factors in a large, international, phase III clinical trial led by investigators at Weill Cornell Medicine, McMaster University, York University and other institutions

18 Sep 2025

Daily orforglipron GLP-1 pill achieves over 11% weight loss in global obesity trial

In a phase 3 trial, once-daily oral orforglipron induced significant, dose-dependent weight loss over 72 weeks in adults with obesity but no diabetes. It also improved multiple cardiometabolic markers with a safety profile similar to other GLP-1 receptor agonists.

18 Sep 2025

Cholesterol control improves but cardiovascular disease still increases in Mexico

Despite improved statin use and cholesterol control, cardiovascular disease risk rose in Mexico between 2016 and 2023, according to a study being presented at ACC Latin America 2025 that used region-specific tools to more accurately predict the local disease burden.

18 Sep 2025

University of Maine team develops sustainable method to cut drug production costs

One of the main factors driving prices in pharmaceuticals, such as cholesterol-lowering drugs and antibiotics, is the cost of production and materials.

17 Sep 2025

A new tool in the fight against obesity: Orforglipron's substantial weight loss results

New research presented at the Annual Meeting of the European Association for the Study of Diabetes in Vienna, Austria (Sept 15-19) and simultaneously published in NEJM shows that daily treatment with the new once-daily GLP-1 agonist orforglipron results in substantial weight loss in people living with obesity that do not have type 2 diabetes.

17 Sep 2025

The mind-gut connection: How emotional eating affects GLP-1 drug success

GLP-1 receptor agonists like Ozempic can be a lifeline for people with diabetes - helping stabilize blood glucose and lose weight which contributes to diabetes complications. But not everyone benefits equally.

17 Sep 2025

Deep learning algorithm uses mammograms and age for heart disease prediction

A new machine learning model developed by The George Institute for Global Health can successfully predict heart disease risk in women by analyzing mammograms. The findings were published today in Heart, the official journal of the British Cardiovascular Society.

17 Sep 2025

Cleveland Clinic study shows lasting benefits of weight-loss surgery over GLP-1 medicines

A large Cleveland Clinic study has found that people with obesity and type 2 diabetes who undergo weight-loss surgery live longer and face fewer serious health problems compared with those treated with GLP-1 receptor agonist medicines alone.

16 Sep 2025

Children show high exposure to PFAS despite regulatory restrictions

These chemical compounds are highly stable and linger in the environment. Thanks to their water-, oil- and stain-repellent properties, they are widely found in everyday items, such as non-stick pans, waterproof clothing, food containers and fire-fighting foams.

15 Sep 2025

Cannabis use may quadruple the risk of developing diabetes

Cannabis use is linked to an almost quadrupling in the risk of developing diabetes, according to an analysis of real-world data from over 4 million adults, being presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 Sept).

15 Sep 2025

Automated AI analysis of mammogram images and age can predict cardiovascular disease risk

An AI algorithm based only on routine mammogram images plus age can predict a woman's risk of major cardiovascular disease as well as standard risk assessment methods, finds research published online in the journal Heart.

13 Sep 2025

Fitness study shows exercise at work can cut chronic disease risks

Researchers evaluate the efficacy of this exercise-based workplace health promotion program at the University of L’Aqulia.

11 Sep 2025

Cholesterol News and Research

Further Reading

New recommendations aim to identify children with familial hypercholesterolemia

Orforglipron pill improves heart and metabolic risk factors in trial

Scientists use blood chemistry to predict disease years before it strikes

Coffee protects the liver by blocking inflammation and scarring, review finds

Glucose-fructose mix found in sugary drinks fuels colorectal cancer metastasis

Replacing red meat with legumes improves heart health and supports weight management

Can eating style affect how well GLP-1 drugs control diabetes and weight?

Study reveals how a little-understood protein contributes to blood vessel leakage

Oral GLP-1 drug orforglipron achieves significant weight loss in global trial

Daily orforglipron GLP-1 pill achieves over 11% weight loss in global obesity trial

Cholesterol control improves but cardiovascular disease still increases in Mexico

University of Maine team develops sustainable method to cut drug production costs

A new tool in the fight against obesity: Orforglipron's substantial weight loss results

The mind-gut connection: How emotional eating affects GLP-1 drug success

Deep learning algorithm uses mammograms and age for heart disease prediction

Cleveland Clinic study shows lasting benefits of weight-loss surgery over GLP-1 medicines

Children show high exposure to PFAS despite regulatory restrictions

Cannabis use may quadruple the risk of developing diabetes

Automated AI analysis of mammogram images and age can predict cardiovascular disease risk

Fitness study shows exercise at work can cut chronic disease risks

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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