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New insights into ribosome collisions and stress response

LMU researchers uncover the mechanism by which ribosomes raise alarms in the cell.

24 Nov 2025

Research explores new solvent strategies to extend shelf life of injectable therapeutics

Sugar-based liquid solvents store crucial injection-based therapeutics such as insulin and vaccines.

22 Nov 2025

New neuron signaling mechanism reveals safer pathway for pain treatment

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead to safer, more effective treatments.

20 Nov 2025

Changes in brain fats play a key role in Alzheimer's development and progression

More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as "lipoid granules," along with the buildup of amyloid-beta (amyloid) plaques and tau protein tangles.

20 Nov 2025

Cancer cells hijack cell death enzyme to regrow after treatment

The emergence of cancer drug resistance remains one of the most pressing problems in cancer care and there is a critical need to devise approaches to mitigate it.

19 Nov 2025

New clinical trial shows promise for shorter TB treatment

New clinical trial results presented by TB Alliance at the Union World Conference on Lung Health show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the potential to improve tuberculosis (TB) treatment when combined with pretomanid and linezolid in a treatment regimen known as "SPaL."

19 Nov 2025

Blocking mir-21 shows promise for slowing bladder cancer growth

Bladder cancer ranks among the ten most common types of cancer worldwide. The main treatment is bladder removal surgery, and despite advances in systemic therapies, recurrence is frequent in the most aggressive forms of the disease.

18 Nov 2025

Cornell team unveils high-resolution tool for tracking kinase activity

Cornell researchers have developed a powerful new biosensor that reveals, in unprecedented detail, how and where kinases – enzymes that control nearly all cellular processes – turn on and off inside living cells.

13 Nov 2025

Scientists discover hidden weakness in Lyme disease bacterium

For decades, Lyme disease has frustrated both physicians and patients alike. Caused by the corkscrew-shaped bacterium Borrelia burgdorferi, the infection, if left untreated, can linger for months, leading to fever, fatigue and painful inflammation.

13 Nov 2025

Collaborative effort advances next-generation therapies for pancreatic and GI cancers

Last year, researchers at the University of California, Riverside, developed a novel "molecular crowbar" strategy to degrade the oncogenic enzyme Pin1, a protein that is overexpressed in many tumors including pancreatic cancer.

12 Nov 2025

Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

Replacing APOE4 with APOE2 in adult mice rapidly reshapes brain lipids and gene expression, even after development is complete. This switch, especially when targeted to astrocytes, reduces amyloid burden, dampens gliosis, and improves associative memory despite E2-like peripheral lipid risks.

12 Nov 2025

Breakthroughs in theranostic nanomaterials for traumatic brain injury management

Traumatic brain injury (TBI) remains one of the most pressing public health challenges, leaving millions with lasting disabilities each year.

12 Nov 2025

Simple blood test may be a better guide treatment for ovarian cancer

More than 300,000 women are diagnosed with ovarian cancer globally each year.

12 Nov 2025

Scientists reveal mathematical law governing limits of biological growth

A research team including a scientist of Earth-Life Science Institute (ELSI) at Institute of Science Tokyo, Japan, has identified a novel principle in biology that mathematically explains why the growth of organisms slows as nutrients become more abundant-a phenomenon known as "the law of diminishing returns."

11 Nov 2025

Study provides insights into the obesity–breast cancer link

Obesity and cancer are two major health challenges of our time, yet the link between them remains only partially understood.

10 Nov 2025

Uppsala researchers develop Trojan horse approach for medulloblastoma treatment

The malignant pediatric brain tumor medulloblastoma is driven by proteins deep within the cancer cells, for which there are often no effective drugs available.

10 Nov 2025

Study uncovers a surprising connection between sugar metabolism and alcohol addiction

Scientists have uncovered a surprising connection between sugar metabolism and alcohol addiction, identifying a potential new therapeutic target for treating alcohol-associated liver disease (ALD) and alcohol use disorder (AUD).

10 Nov 2025

Complete revascularization reduces the risk of death from cardiovascular causes

Opening all blocked arteries with stents in patients with a heart attack, known as complete revascularization, reduces the risk of death from cardiovascular causes, death from any cause and future heart attacks compared with opening only culprit artery causing the heart attack according to a new, large international study led by researchers at the Population Health Research Institute (PHRI), a joint organization of McMaster University and Hamilton Health Sciences.

10 Nov 2025

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

Regular orange juice consumption reprograms immune-cell gene activity linked to blood pressure, lipid metabolism, and inflammation in healthy adults. The molecular effects differ by body weight, suggesting BMI-tailored benefits from this everyday beverage.

9 Nov 2025

New molecule offers a promising avenue to treat triple-negative breast cancer

A new molecule developed by researchers at Oregon Health & Science University offers a promising avenue to treat intractable cases of triple-negative breast cancer - a form of cancer that is notoriously aggressive and lacks effective treatments.

7 Nov 2025

Enzyme News and Research

New insights into ribosome collisions and stress response

Research explores new solvent strategies to extend shelf life of injectable therapeutics

New neuron signaling mechanism reveals safer pathway for pain treatment

Changes in brain fats play a key role in Alzheimer's development and progression

Cancer cells hijack cell death enzyme to regrow after treatment

New clinical trial shows promise for shorter TB treatment

Blocking mir-21 shows promise for slowing bladder cancer growth

Cornell team unveils high-resolution tool for tracking kinase activity

Scientists discover hidden weakness in Lyme disease bacterium

Collaborative effort advances next-generation therapies for pancreatic and GI cancers

Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

Breakthroughs in theranostic nanomaterials for traumatic brain injury management

Simple blood test may be a better guide treatment for ovarian cancer

Scientists reveal mathematical law governing limits of biological growth

Study provides insights into the obesity–breast cancer link

Uppsala researchers develop Trojan horse approach for medulloblastoma treatment

Study uncovers a surprising connection between sugar metabolism and alcohol addiction

Complete revascularization reduces the risk of death from cardiovascular causes

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

New molecule offers a promising avenue to treat triple-negative breast cancer

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