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Trial shows no meaningful gains with mavacamten in nonobstructive hypertrophic cardiomyopathy

Mavacamten treatment at 48 weeks was not associated with significant improvements in patient-reported health status or peak oxygen consumption compared with placebo in patients with symptomatic nonobstructive hypertrophic cardiomyopathy, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in New England Journal of Medicine.

1 Sep 2025

REBOOT trial finds no benefit of beta blockers after uncomplicated heart attacks

Beta blockers-drugs commonly prescribed for a range of cardiac conditions, including heart attacks-provide no clinical benefit for patients who have had an uncomplicated myocardial infarction with preserved heart function.

30 Aug 2025

Sharp rise in pertussis hospitalizations highlights need for timely vaccination

Pertussis, commonly known as whooping cough, is a vaccine-preventable disease which continues to circulate even in areas where vaccination coverage is high, and outbreaks may still occur. A study published in Eurosurveillance and conducted at Meyer Children's Hospital in Florence, Italy, has found a sharp increase in hospitalisations for pertussis among children and adolescents (patients aged 16 years or under) in 2024.

29 Aug 2025

Most Americans unaware that early prostate cancer shows no symptoms

A recent survey commissioned by The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) focused on Americans' awareness of the signs and symptoms of prostate cancer.

28 Aug 2025

High protein diet linked to increased risk of cancer-associated venous thromboembolism

Next to cancer recurrence or progression, cardiovascular diseases are the leading causes of death in cancer survivors.

28 Aug 2025

Do GLP-1 drugs shrink your muscles? New study explains the risks and what to do

GLP-1 receptor agonists are transforming obesity and diabetes care, but may reduce skeletal muscle mass, raising concerns about sarcopenic obesity. This comprehensive review explores the mechanisms, clinical implications, and mitigation strategies, including exercise, protein intake, and adjunct therapies.

26 Aug 2025

Researchers discover why smoking tobacco helps people with ulcerative colitis

Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered why smoking tobacco helps people suffering from ulcerative colitis, a chronic disease typified by inflammation of the large intestine.

25 Aug 2025

The challenges of shift work on diet, sleep, and well-being

Healthcare shift workers face dietary and sleep challenges, leading to burnout and health issues. Effective interventions are crucial for their well-being.

25 Aug 2025

INTEGRA's PIPETBOY GENIUS provides superior ergonomics and liquid control for cell culture

Scientists at the Max Planck Institute of Biochemistry in Munich, Germany, use 4 PIPETBOY GENIUS serological pipet controllers from INTEGRA Biosciences to streamline their cell culture workflows.

From INTEGRA Biosciences 20 Aug 2025

How a Réunion Island outbreak sparked France’s record chikungunya season

Mainland France recorded its earliest-ever local chikungunya outbreaks in May 2025, with 10 clusters (27 cases) across five regions, driven by travelers importing the virus from Réunion Island. The surge highlights growing vulnerability to mosquito-borne diseases in Europe as Aedes albopictus expands northward.

18 Aug 2025

Study links COVID-19 infection to accelerated blood vessel aging in women

A Covid infection, particularly in women, may lead to blood vessels aging around five years, according to research published in the European Heart Journal on 18th August, 2025.

18 Aug 2025

Lifestyle choices and irregular sleep patterns drive weekend spike in OSA severity

Late nights, alcohol, and smoking on weekends may be doing more than disrupting your Monday mornings, they could be triggering a newly identified sleep health concern known as 'social apnea', warn researchers from Flinders University.

13 Aug 2025

Study shows how targeted communication can aid online patient engagement

A new study by researchers at the University of Amsterdam (UvA) and Amsterdam UMC shows how targeted communication can help patients engage more with online health communities.

13 Aug 2025

Study links baseline fatigue with higher inflammation in breast cancer survivors

For many breast cancer survivors, fatigue may linger long after treatment ends, which can have a significant impact on cognitive function, ability to work, and overall quality of life.

12 Aug 2025

Polyphenols and exercise show promise in fighting gliomas

A new review in Food Science & Nutrition highlights how combining dietary polyphenols with structured exercise can enhance brain function, regulate epigenetics, and support glioma management. The authors outline mechanisms, patient-centered strategies, and research gaps for turning this synergy into clinical practice.

12 Aug 2025

Contact lens with OLED offers safer simpler retinal diagnosis

Electroretinography (ERG) is an ophthalmic diagnostic method used to determine whether the retina is functioning normally.

12 Aug 2025

Plant-based protein blends can match whey for muscle recovery

Recent research reveals effective plant-based protein blends for muscle recovery, highlighting the need for higher doses to match whey's benefits.

12 Aug 2025

Researchers develop machine learning models to identify biomarkers for chronic fatigue syndrome

When cells expire, they leave behind an activity log of sorts: RNA expelled into blood plasma that reveal changes in gene expression, cellular signaling, tissue injury and other biological processes.

11 Aug 2025

Many patients with high-risk myelodysplastic syndromes do not receive guideline-recommended treatment

Most patients with high-risk myelodysplastic syndromes (MDS) do not receive guideline-recommended treatment with hypomethylating agents (HMAs), according to results published in Blood Neoplasia.

6 Aug 2025

Are all healthy diets equal or does food processing make a difference?

A randomized crossover trial in the UK found that both ultra-processed (UPF) and minimally processed food (MPF) diets, when aligned with national guidelines, led to weight loss in adults with overweight or obesity. However, the MPF diet produced significantly greater reductions in weight, fat mass, and food cravings, highlighting the added benefits of limiting food processing.

5 Aug 2025

Fatigue News and Research

Trial shows no meaningful gains with mavacamten in nonobstructive hypertrophic cardiomyopathy

REBOOT trial finds no benefit of beta blockers after uncomplicated heart attacks

Sharp rise in pertussis hospitalizations highlights need for timely vaccination

Most Americans unaware that early prostate cancer shows no symptoms

High protein diet linked to increased risk of cancer-associated venous thromboembolism

Do GLP-1 drugs shrink your muscles? New study explains the risks and what to do

Researchers discover why smoking tobacco helps people with ulcerative colitis

The challenges of shift work on diet, sleep, and well-being

INTEGRA's PIPETBOY GENIUS provides superior ergonomics and liquid control for cell culture

How a Réunion Island outbreak sparked France’s record chikungunya season

Study links COVID-19 infection to accelerated blood vessel aging in women

Lifestyle choices and irregular sleep patterns drive weekend spike in OSA severity

Study shows how targeted communication can aid online patient engagement

Study links baseline fatigue with higher inflammation in breast cancer survivors

Polyphenols and exercise show promise in fighting gliomas

Contact lens with OLED offers safer simpler retinal diagnosis

Plant-based protein blends can match whey for muscle recovery

Researchers develop machine learning models to identify biomarkers for chronic fatigue syndrome

Many patients with high-risk myelodysplastic syndromes do not receive guideline-recommended treatment

Are all healthy diets equal or does food processing make a difference?

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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