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Comprehensive study of Middle Eastern DNA reveals ancient human adaptation to agriculture, climate change

The most comprehensive study so far of genetic diversity in the Middle East has given a glimpse into the lives of ancient humans who lived through such seismic events as the development of agriculture and the formation of the Arabian Desert.

4 Aug 2021

Next-generation CRISPR tools and therapies improved by modified RNA guides

A new type of gene-editing tool, CRISPR-Cas13, has shown promise in RNA targeting. Previous studies have shown the tool as a potential treatment method for viral diseases, including coronavirus disease (COVID-19).

3 Aug 2021

PROTEIN-ID project aims to develop a device able to generate identity card of proteins

A device able to generate proteins identity card: this is the ambitious goal of the "PROTEIN ID" project, funded by the European Union with about 3 million euro for the next 3 years and coordinated by the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology).

3 Aug 2021

Innovative strategy for early diagnosis of schizophrenia

An innovative strategy that analyzes a region of the genome offers the possibility of early diagnosis of schizophrenia, reports a team led by researchers at Baylor College of Medicine.

3 Aug 2021

Purifying selection drives time-dependency of short-term mutation rates in SARS-CoV-2 and pH1N1 influenza

A new paper, available on the medRxiv* preprint server, indicates the adaptation undergone by the SARS-CoV-2 molecular genome and the pH1N1 influenza pandemic strain during the first year of their spread, separately. Using statistical and phylogenetic skills, the researchers present a picture of the emergence, rates of change, and of growth, of these two viruses as time passes.

3 Aug 2021

Study conducts systematic review of the pre- and asymptomatic SARS-CoV-2 transmission

Researchers at Oxford University, UK, have conducted a systematic review of the available studies to address the role of presymptomatic and asymptomatic transmission of SARS-CoV-2.

3 Aug 2021

Antibiotic-resistant salmonella bacteria packs a punch for U.S. travelers

One type of the salmonella bacteria is much more likely to cause disease and fend off frontline antibiotics when acquired in Europe, Asia, and parts of Africa rather than domestically in the United States.

2 Aug 2021

Pfizer moves towards an oral anti-COVID-19 therapy

Researchers in the United States have described a novel antiviral agent against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) currently being evaluated in clinical trials as a treatment for coronavirus disease 2019 (COVID-19).

2 Aug 2021

Researchers discover titanium oxide nanoparticle that recognizes SARS-CoV-2’s non-structural protein 1

A pioneering study reports on the interaction of a tailored titanium oxide nanoparticle (NP) with the full-length SARS-CoV-2 non-structural protein 1 (nsp1). This should be of value in developing new therapeutic tools against coronaviruses that act by targeting their proteins. It could also help map the structure of activated proteins.

2 Aug 2021

Polyuridine sequence of mouse coronavirus can be targeted to prevent host cell death

A new study reports the use of a modified deoxyribonucleic acid (DNA) oligonucleotide that has a 3’ polyadenine (polyA) tail to bind to the 5’-polyU tract in the mouse coronavirus (MHV-A59). Treatment of mouse cells infected with MHV-A59 with this molecule led to a marked reduction in cell deaths.

2 Aug 2021

Could novel biosensors facilitate SARS-CoV-2 antiviral drug research?

An intriguing new study presents a novel approach to biosensor-based evaluation of promising drugs that could inhibit the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) via its 3C-like protease (3CLpro), a viral protease.

2 Aug 2021

In-depth sequencing of SARS-CoV-2 variants crucial in controlling outbreaks

In this interview, News-Medical speaks to Professor Dana Crawford about her research efforts during the COVID-19 pandemic.

2 Aug 2021

Study examined 1,497 full-vaccinated healthcare workers for breakthrough infections

A new study published in The New England Journal of Medicine found that in a very small number of cases, people with breakthrough infections might suffer long-lasting COVID-19 symptoms.

2 Aug 2021

Finding potential microRNAs from humans and plants against SARS-CoV-2

A new study focuses on the identification of probable miRNA candidates from three medicinal plants.

1 Aug 2021

Newly identified genetic mutation causes rare, early onset inflammatory bowel disease

Johns Hopkins Medicine researchers, in collaboration with national and international researchers, have identified a genetic mutation in a small number of children with a rare type of inflammatory bowel disease.

30 Jul 2021

New integrative NGS panel for analysis of standard and novel biomarkers in lymphoid neoplasms

Increasing knowledge about genomic biomarkers has facilitated better monitoring and personalized management of patients with B-cell malignant tumors.

29 Jul 2021

World's most sophisticated COVID-19 sequencing system

In response to the ongoing SARS-CoV-2 infections in the United Kingdom, the COVID-19 Genomics UK (COG-UK) consortium was formed to rapidly sequence SARS-CoV-2 genomes as part of a national-scale genomic surveillance strategy.

29 Jul 2021

Mass spectrometry used to develop N-glycosylation profiles for SARS-CoV-2 D614G

A new study has characterized and compared the N-glycosylation of the wild type (S-614D) and variant (S-614G) of SARS-CoV-2 S glycoproteins using MS techniques.

28 Jul 2021

A quantitative assessment of SARS-CoV-2 bioaerosol production

In an effort to improve the sensitivity and sample recovery of mask sampling, researchers developed a mask sampling tool to assess bioaerosol variation.

28 Jul 2021

Cats could be a valuable model organism for geneticists, expert says

Although cats have lived alongside humans for millennia, it remains a dogs' world. This bias has historically bled into science as well.

28 Jul 2021

Genome News and Research

Comprehensive study of Middle Eastern DNA reveals ancient human adaptation to agriculture, climate change

Next-generation CRISPR tools and therapies improved by modified RNA guides

PROTEIN-ID project aims to develop a device able to generate identity card of proteins

Innovative strategy for early diagnosis of schizophrenia

Purifying selection drives time-dependency of short-term mutation rates in SARS-CoV-2 and pH1N1 influenza

Study conducts systematic review of the pre- and asymptomatic SARS-CoV-2 transmission

Antibiotic-resistant salmonella bacteria packs a punch for U.S. travelers

Pfizer moves towards an oral anti-COVID-19 therapy

Researchers discover titanium oxide nanoparticle that recognizes SARS-CoV-2’s non-structural protein 1

Polyuridine sequence of mouse coronavirus can be targeted to prevent host cell death

Could novel biosensors facilitate SARS-CoV-2 antiviral drug research?

In-depth sequencing of SARS-CoV-2 variants crucial in controlling outbreaks

Study examined 1,497 full-vaccinated healthcare workers for breakthrough infections

Finding potential microRNAs from humans and plants against SARS-CoV-2

Newly identified genetic mutation causes rare, early onset inflammatory bowel disease

New integrative NGS panel for analysis of standard and novel biomarkers in lymphoid neoplasms

World's most sophisticated COVID-19 sequencing system

Mass spectrometry used to develop N-glycosylation profiles for SARS-CoV-2 D614G

A quantitative assessment of SARS-CoV-2 bioaerosol production

Cats could be a valuable model organism for geneticists, expert says

Genetics & Genomics - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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