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New findings raise questions about process used to identify experimental drug

A study by National Institutes of Health (NIH) researchers has revealed surprising new insights into the process used to initially identify an experimental drug now being tested in people with cystic fibrosis and muscular dystrophy.

3 Feb 2009

Major malaria breakthrough

A team of Monash University researchers led by Professor James Whisstock has made a major breakthrough in the international fight against malaria, which claims the life of a child across the world every 30 seconds.

3 Feb 2009

Green tea may counteract anticancer effects of cancer therapy, bortezomib (Velcade)

Green tea products have become regarded as a valuable health supplement, as studies have shown evidence of its benefit against a variety of diseases, including cancer.

3 Feb 2009

Fractures due to osteoporosis in seniors a signal for premature death

An Australian study has found that people over 60 years old who have had a fracture because of reduced bone density, or osteoporosis, face a higher risk of death over the next 5 to 10 years compared to the general population and those who experience additional fractures increase their risk of death further.

3 Feb 2009

Genetics may predict risk for relapse among alcohol-dependent patients

In Poland, alcohol dependence (AD) affects about four percent of the population, causing about 10,000 deaths per year.

3 Feb 2009

Revealed! - Missing link in how cells protect themselves from cancer

An international team of scientists have discovered a missing link in the method used by cells to protect themselves from cancer.

3 Feb 2009

Drugs may be 'magic bullet' for infants born with rare form of diabetes

Infants born with a rare form of inherited diabetes might avoid irreversible damage to their pancreases if they are treated immediately with sulfonylurea drugs rather than insulin, according to a new report in the February 4th issue of Cell Metabolism , a Cell Press publication.

3 Feb 2009

New inhibitors could be new class of cancer drugs

A team of Vanderbilt University Medical Center investigators has developed a group of chemical compounds that could represent a new class of drugs for treating cancer.

3 Feb 2009

Robot scientist promises to dig up new drugs

A robot scientist that can make informed guesses about how effective different chemical compounds will be at fighting different diseases could revolutionise the pharmaceutical industry by developing more effective treatments more cheaply and quickly than current methods.

3 Feb 2009

Scientists use non-invasive approach to watch chemo drug working inside the living body in real time

For many cancer patients, chemotherapy can be worse than cancer itself.

2 Feb 2009

Fasudil could reduce risk of Alzheimer's

A drug used to improve blood flow to the brain also could help improve learning and memory and reduce the risk of Alzheimer's disease, according to a new study released today by investigators at the Translational Genomics Research Institute (TGen) and Arizona State University.

2 Feb 2009

Teens who frequently go out with friends more likely to use marijuana

Marijuana use appears to have decreased among most European and North American adolescents between 2002 and 2006, and those who went out with friends on fewer evenings of the week were less likely to report using the drug, according to a report in the February issue of Archives of Pediatrics & Adolescent Medicine.

2 Feb 2009

New technology rapidly detects tumor response to chemotherapy

New technology developed by Duke University bioengineers can help clinicians more precisely detect whether specific cancer drugs are working, and should give basic researchers a powerful new tool to better understand the underlying mechanisms of cancer development.

2 Feb 2009

Sedative dexmedetomidine may offer advantages over agents often used for sedation in ICU

Use of the sedative dexmedetomidine for critically ill patients resulted in less time on a ventilator and less delirium compared to patients administered a more commonly used drug, according to a study in the February 4 issue of JAMA, the Journal of the American Medical Association.

2 Feb 2009

New technique images tumor vessel leakiness to predict breast cancer chemotherapy outcome

Chemotherapy is an integral part of modern cancer treatment, but it's not always effective.

2 Feb 2009

Insulin may slow or prevent damage caused by toxic proteins in Alzheimer's disease

A Northwestern University-led research team reports that insulin, by shielding memory-forming synapses from harm, may slow or prevent the damage and memory loss caused by toxic proteins in Alzheimer's disease.

2 Feb 2009

Gene expression signature associated with survival in advanced ovarian cancer

A new study published this week in the open-access journal PLoS Medicine identifies molecular pathways associated with outcomes in ovarian cancer.

2 Feb 2009

Genetic change prevents cell death in mouse model of Parkinson's disease

By shifting a normal protective mechanism into overdrive, a University of Wisconsin-Madison scientist has completely shielded mice from a toxic chemical that would otherwise cause Parkinson's disease.

2 Feb 2009

Study looks at effects of 9/11 attacks on drink driving

The September 11 terrorist attacks had a profound impact on this country's psyche.

2 Feb 2009

The end of sex as we once knew it

Women are not from Venus any more than men are from Mars. But even though both sexes are perfectly terrestrial beings, they are not lacking in other differences. And not only in their reproductive organs and behavior, either, but in such unsexy characteristics as the propensity for drug abuse, fine motor control, reaction to stress, moods and many brain structures.

2 Feb 2009