Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

New biomarker paves way for personalized bladder cancer treatments

Researchers have identified a potential new target for the treatment of a particularly aggressive form of bladder cancer, in the form of microRNA.

2 Jul 2018

Streamlining and translating basic science discoveries into the clinic

To make sure that good ideas to enhance healthcare are not lost due to a lack of resources, a growing number of centers at Penn Medicine organize forums to pitch ideas to improve medical devices and technology, hold annual competitions to fund studies to improve patient care while keeping costs down, and sponsor seed grants for programs focused on patients who need individualized tailoring of their treatment.

2 Jul 2018

Research shows why new cancer therapies fail to work on some patients

University of Otago research provides insights into an underlying mechanism that could explain why new cancer therapies to help treat metastatic melanoma do not always work on patients, paving the way for predicting which patients will benefit from certain drugs.

30 Jun 2018

Scientists focus on critical regulatory protein to find clues on cancer, neurodegenerative diseases

James McNew's and Michael Stern's biochemical hunt for the root cause of a rare, paralyzing genetic disorder is a 10-year quest that's taken an unexpected turn toward everyday killers such as Alzheimer's disease, cancer and aging.

30 Jun 2018

Scientists discover way to increase efficiency of mature blood production in a dish

Scientists at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago discovered a way to increase the efficiency of mature blood production in a dish.

29 Jun 2018

Obesity together with aging may contribute to development of Alzheimer's disease

A new study suggests that when a high-fat, high-sugar diet that leads to obesity is paired with normal aging, it may contribute to the development of Alzheimer's disease.

29 Jun 2018

New mouse model could shed light on autism subtype

Researchers at the UC Davis MIND Institute have created a mouse model for maternal antibody- related (MAR) autism spectrum disorder that closely mimics the physiology and behaviors seen in people with this form of ASD.

29 Jun 2018

Scientists pinpoint new mechanism to explain progression of Alzheimer's disease

Scientists have pinpointed minute exosomes as the main vehicle that allow the spread of toxic proteins that trigger the onset of Alzheimer's Disease across a person's brain network.

29 Jun 2018

Achieving the WHO’s Global Action Plan for Dementia

One year on from the WHO's Global Action Plan for Dementia, Dr. Matthew Norton from Alzheimer's Research UK discusses the steps that have been taken so far, and whether we are likely to meet the 2025 target.

28 Jun 2018

Researchers target K17 in the fight against pancreatic cancer

Keratin 17 (K17), a protein that promotes cancer, may prove to be a key target gene in the battle against pancreatic cancer.

28 Jun 2018

Researchers discover immune cells that create and sustain chronic inflammatory bowel disease

In preclinical experiments, Laurie Harrington, Ph.D., and colleagues at the University of Alabama at Birmingham have discovered a subset of immune cells that create and sustain chronic inflammatory bowel disease.

27 Jun 2018

Researchers develop new approach for studying Cryptosporidium in healthy human tissues

Washington State University researchers have developed a new approach for studying Cryptosporidium, a waterborne gastrointestinal parasite now recognized as one of the leading causes of potentially life-threatening diarrheal disease in young children worldwide.

26 Jun 2018

A systematic approach towards diagnosis and treatment of rheumatoid arthritis

Rheumatoid Arthritis: A systematic approach (edited by Dr. Syuichi Koarada) comprehensively covers each aspect of the pathology, diagnosis and treatment of rheumatoid arthritis.

26 Jun 2018

UVA research shows true nature of immune cells blamed in Alzheimer's

Immune cells commonly blamed in Alzheimer's and other neurodegenerative diseases are actually precision cleaning machines protecting the central nervous system, new research from the University of Virginia School of Medicine shows.

26 Jun 2018

Researchers discover immune profile for effective cancer immunotherapy

In a new study published online June 25, 2018 in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs known as checkpoint inhibitors.

25 Jun 2018

UC San Diego launches new bacteriophage therapy center

With microbial resistance to antibiotics growing into a major global health crisis, researchers at University of California San Diego School of Medicine, in collaboration with national research institutions and private industry, are leveraging hard-won expertise to exploit a natural viral enemy of pathogenic bacteria, creating North America's first Center for Innovative Phage Applications and Therapeutics

22 Jun 2018

Researchers discover shared genetic basis for psychiatric disorders

A new study conducted by Spanish researchers has shown that psychiatric disorders, but not non-psychiatric neurological disorders have a shared genetic basis.

22 Jun 2018

'Antifreeze' molecules may hold key to better treatments for brain injuries

The key to better treatments for brain injuries and disease may lie in the molecules charged with preventing the clumping of specific proteins associated with cognitive decline and other neurological problems, researchers from the Perelman School of Medicine at the University of Pennsylvania report in a new study published in Neurobiology of Disease.

22 Jun 2018

Researchers report unusually high levels of herpesvirus in the brains of people with Alzheimer's disease

Two strains of human herpesvirus - human herpesvirus 6A (HHV-6A) and human herpesvirus 7 (HHV-7) - are found in the brains of people with Alzheimer's disease at levels up to twice as high as in those without Alzheimer's, researchers from the Icahn School of Medicine at Mount Sinai report.

21 Jun 2018

Study finds cell-free DNA profiling as versatile method to monitor UTIs

Using shotgun DNA sequencing, Cornell University researchers have demonstrated a new method for monitoring urinary tract infections that surpasses traditional methods in providing valuable information about the dynamics of the infection as well as the patient's biological response.

21 Jun 2018