Drug Discovery News and Research

RSS

The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

PPD licenses dyslipidemia statin from Ranbaxy

Ranbaxy Laboratories and PPD, Inc. have announced that PPD has acquired an exclusive worldwide license to develop, manufacture and market Ranbaxy's novel statin for the treatment of dyslipidemia.

27 Feb 2007

New patented technology for next generation of DNA and RNA microarrays

A novel invention developed by a scientist from New York Institute of Technology (NYIT) could revolutionize biological and clinical research and may lead to treatments for cancer, AIDS, Alzheimer's, diabetes, and genetic and infectious diseases.

13 Feb 2007

New technologies boost production of malaria drug artemisinin

New technologies that make the large-scale extraction of a natural antimalarial ‘wonder drug' both cheaper and greener are to be developed and trialled in a new European effort.

12 Feb 2007

Natural molecules to create pseudo-cell factories

Carnegie Mellon University's Philip LeDuc predicts the use of artificially created cells could be a potential new therapeutic approach for treating diseases in an ever-changing world.

7 Feb 2007

Ranbaxy and GlaxoSmithKline form alliance

Ranbaxy Laboratories announced today that the Company and GlaxoSmithKline have signed a new, multiyear R&D agreement that modifies and expands the terms of their strategic alliance established in 2003 to provide Ranbaxy expanded drug-development responsibilities and further financial opportunities.

6 Feb 2007

4SC granted U.S. patent for drug to treat rheumatoid arthritis

Martinsried-based drug discovery and development company 4SC AG announced today that the US Patent and Trademark Office (ASPTO) has granted the patent with the US patent number 7,176,241 for its drug candidate SC12267.

6 Feb 2007

Apolipoprotein E gene raises newborns' cerebral palsy risk

Apolipoprotein E (APOE), a gene associated with heightened risk for Alzheimer's disease in adults, can also increase the likelihood that brain-injured newborns will develop cerebral palsy, researchers at Children's Memorial Research Center have discovered.

5 Feb 2007

FoxOs shown to be potential new targets for cancer drugs

In an elegant, multiple-gene knockout experiment, a team of Boston scientists has discovered that a trio of molecules, called FoxOs, are fundamentally critical in preventing some cancers, maintaining blood vessel stability, and in keeping blood-forming stem cells healthy.

29 Jan 2007

Emory University announces new health institute

Emory University announced today a new Global Health Institute that will help address the most pressing health challenges around the world, particularly in poorer nations.

10 Jan 2007

BIO urges Congress to pass Stem Cell Research Enhancement Act

Jim Greenwood, president and CEO of the Biotechnology Industry Organization (BIO), has issued the following statement on H.R. 3, the Stem Cell Research Enhancement Act of 2007.

9 Jan 2007

Amphora sells oncology target to Genentech

Amphora Discovery Corporation, a small molecule drug discovery company, announced today that it has entered into an agreement with Genentech, Inc. pursuant to which Genentech will purchase Amphora's entire program for an unnamed oncology target with the potential to treat multiple oncology indications.

9 Jan 2007

Cytogen issued new patent covering oral drug delivery agents

Cytogen Corporation has announced that it has been issued United States patent number 7,135,457 covering its oral drug delivery agents - random peptide compositions that bind to gastro-intestinal tract (GIT) transport receptors.

28 Nov 2006

Master stem cell capable of producing new heart tissue

Researchers in the United States believe they have discovered a "master" embryonic cardiac stem cell.

22 Nov 2006

New protein structure found - important for drug discovery

Understanding and replicating the diverse ways in which cellular proteins fold and interconnect is key to understanding life processes and major disorders, such as Parkinson's disease.

15 Nov 2006

Bionomics delivers on milestones for cancer, anxiety and multiple sclerosis programs

Australian drug discovery company Bionomics Limited today updated shareholders at its Annual General Meeting on the recent progress of its anti-cancer drug BNC105 and drug discovery programs in anxiety and Multiple Sclerosis.

8 Nov 2006

Lab-on-a-chip nanoscale array monitors cellular processes

Researchers at Tel-Aviv University in Israel have developed a lab-on-a-chip device that can incorporate enzymes and even living cells in a nanoscale array capable of monitoring electrochemical reactions.

30 Oct 2006

New study emphasizes the importance of metabolomics to the advent of personalized medicine

International experts have collaborated on a comprehensive collection of reviews focusing on the emerging interface between metabolomics and pharmacogenomics.

24 Oct 2006

New method of developing antibiotics

University of Minnesota and University of Michigan researchers have discovered a new method of developing antibiotics, an important step in fighting the growing number of drug-resistant infections.

12 Sep 2006

New map for human genome expression

ExonHit Therapeutics has announced the completion of a new messenger RNA (transcripts) map coming from human genome expression.

5 Sep 2006

New drug improves blood flow in diseased arteries

A new drug has been shown to improve blood flow in diseased arteries, reducing the risk of high blood pressure and heart attacks, a Monash University study published today reveals.

4 Sep 2006