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Study finds evidence of injury in placentas from COVID-19-positive pregnant women

The placentas from 16 women who tested positive for COVID-19 while pregnant showed evidence of injury, according to pathological exams completed directly following birth, reports a new Northwestern Medicine study.

22 May 2020

Study identifies risk factors for severe COVID-19 or death in the UK

Age, male sex, obesity, and underlying illness have emerged as risk factors for severe covid-19 or death in the UK, according to the largest cohort study to date published by The BMJ today.

22 May 2020

Study reveals mechanism involved in the development of diabetes, fatty liver

A research group including Professor OGAWA Wataru (Division of Diabetes and Endocrinology, Kobe University Graduate School of Medicine) and Project Associate Professor HOSOOKA Tetsuya (Division of Development of Advanced Therapy for Metabolic Disease, Kobe University Graduate School of Medicine) has clarified the mechanism underlying the development of diabetes and non-alcoholic steatohepatitis (NASH), a severe form of fatty liver.

22 May 2020

Indica Labs and Octo announce launch of online COVID Digital Pathology Repository

Indica Labs, a leading provider of computational pathology software, and Octo, a premiere information technology systems provider to the U.S. Federal Government, are pleased to announce the online COVID Digital Pathology Repository, a virtual collection of high resolution microscopic COVID-related human tissue images hosted at the National Institutes of Health.

22 May 2020

Environmental chemicals linked to changes in the gut microbiome and health

The microbes that inhabit our bodies are influenced by what we eat, drink, breathe and absorb through our skin, and most of us are chronically exposed to natural and human-made environmental contaminants.

21 May 2020

COVID-19 in farmed Mink in the Netherlands

A new study published on the preprint server bioRxiv in May 2020 reports the development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in farmed mink in two locations in the Netherlands.

21 May 2020

Researchers receive $5 million to study two types of parasitic infection

Researchers at Washington University School of Medicine in St. Louis have received two grants from the National Institutes of Health totaling more than $5 million to study two types of parasitic worm infection that cause devastating illness in millions of people worldwide.

21 May 2020

Scientists use new model to develop cancer stem cells

Liver cancer is one of the deadliest cancers. It is insidious and does not present symptoms until it has progressed considerably, at which point, treatment options are limited and chances of survival are low. The most common type of liver cancer is hepatocellular carcinoma (HCC).

21 May 2020

Study focuses on COVID-19 patients with inflammatory rheumatic diseases

The ongoing COVID-19 pandemic has caused nearly five million cases and over 327,000 deaths worldwide. The signs and symptoms of this disease are varied, although there are typical features which assist diagnosis.

20 May 2020

'Senolytic' therapy blunts liver tumor progression in animal models

"Senotherapy," a treatment that uses small molecule drugs to target "senescent" cells, or those cells that no longer undergo cell division, blunts liver tumor progression in animal models according to new research from a team led by Celeste Simon, Ph.D., a professor of Cell and Developmental Biology in the Perelman School of Medicine at the University of Pennsylvania and scientific director of the Abramson Family Cancer Research Institute.

20 May 2020

Diagnosis and treatment of nonalcoholic fatty liver disease

Gastroenterology, the official journal of the American Gastroenterological Association (AGA), has released a special issue providing clinicians and researchers an up-to-date resource on the risk factors, natural history, diagnosis and treatment of nonalcoholic fatty liver disease (NAFLD).

20 May 2020

Chemicals found in consumer products could contribute to onset of lipid-related diseases

Chemical compounds found in many consumer products could be major contributors to the onset of lipid-related diseases, such as obesity, in humans, according to a Baylor University study.

19 May 2020

MGH researchers identify potential molecular targets for ALD drug development

Alcohol-related liver disease (ALD) is a deadly condition affecting more than 150 million people worldwide with no treatment available besides transplant.

19 May 2020

DZD researchers discover additional genetic cause for non-alcoholic fatty liver disease

In Germany about 18 million people suffer from non-alcoholic fatty liver. The causes of this disease are manifold and include environmental as well as genetic factors.

19 May 2020

Phase IIB clinical trial initiated for treating hepatitis B-associated liver cancer

The first patients have been dosed in a multi-regional Phase IIB randomized, placebo-controlled clinical trial for the treatment of hepatitis B-associated liver cancer.

19 May 2020

Fewer traffic collisions during shutdown means longer waits for organ donations

On Day Two of the San Francisco Bay Area's stay-at-home orders in March, Nohemi Jimenez got into her car in San Pablo, California, waved goodbye to her 3-year-old son and drove to her regular Wednesday dialysis appointment.

19 May 2020

Binge drinking causes' drunkorexia in young women

Binge drinking may lead to a condition called "drunkorexia," a new study from the University of South Australia found.

18 May 2020

Study shows how cancer protein changes may accelerate tumorigenesis and metastasis

Understanding the genetic mutations and protein changes that take place in the progression of cancer is key to its treatment. Mutations in the gene TP53 and concomitant mutant p53 proteins in cancer cells have become notorious over the course of multiple studies of several different types of cancers.

18 May 2020

ECMO machine can be useful for treating critically ill COVID-19 patients

When COVID-19 patients are critically ill, the biggest threat to their lives is lung dysfunction. If their lungs don't work, their blood can't circulate enough oxygen to the brain, the liver and other organs.

18 May 2020

People with Hepatitis D have up to three times the risk of developing fatal liver cancer

Of all the hepatitis viruses, D is the most poorly known. This small virus, which can only infect people already infected with Hepatitis B, has so far been little studied.

18 May 2020