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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Researchers develop new method to quantify protein droplets involved in neurodegenerative diseases

Some proteins in cells can separate into small droplets like oil droplets in water, but faults in this process may underlie neurodegenerative diseases in the brains of older people. Now, Rutgers researchers have developed a new method to quantify protein droplets involved in these diseases.

13 Aug 2021

Novel CRISPR-based technique could inspire a new class of medical diagnostics

Scientists have repurposed the genetic modification technology CRISPR to identify antibodies in patient blood samples in a move that could inspire a new class of medical diagnostics in addition to a host of other applications.

13 Aug 2021

Researchers develop a new way to tag tumor cells to understand cancer treatment resistance

Despite tremendous advances in medicine, tumors are challenging to cure because they are made up of heterogeneous cells.

13 Aug 2021

Study uncovers a subset of human short introns spliced out by a distinct mechanism

The interrupted non-coding regions in pre-mRNAs, termed “introns,” are excised by “splicing” to generate mature coding mRNAs that are translated into proteins.

13 Aug 2021

Discovery of highly potent neutralizing monoclonal antibodies against SARS-CoV-2

A new study published in the journal Nature Communications has reported two neutralizing antibodies, namely, nCoVmab1 and nCoVmab2, which are potent against SARS-CoV-2.

13 Aug 2021

How replication and recombination contribute to emergence of SARS-CoV-2 variants

The coronavirus disease 2019 (COVID-19) pandemic has been caused by the rapid outbreak of a novel coronavirus, namely, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). SARS-CoV-2 was first reported in late December 2019 in Wuhan, China. Since then, the virus has already claimed more than 4.3 million lives worldwide.

13 Aug 2021

Study highlights the significance of screening for pre-cancerous Barrett’s esophagus

Abnormal cells that go on develop into oesophageal cancer – cancer that affects the tube connecting the mouth and stomach – start life as cells of the stomach, according to scientists at the University of Cambridge.

13 Aug 2021

Optical nanoscopy reveals how SARS-CoV-2 infection alters human airway cells

How do viruses reorganize host cells with spatial and molecular specificity? Researchers from the Netherlands provided new insights in a recent study posted to the bioRxiv* preprint server, where they use optical nanoscopy to look at severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-triggered changes in primary human airway cells.

12 Aug 2021

Innovative therapeutic platform for blood-to-brain delivery of antisense oligonucleotide therapy

Antisense oligonucleotide (ASO) therapy has the potential to ameliorate many neurodegenerative diseases at the genetic level to suppress the production of harmful proteins or non-coding RNAs.

12 Aug 2021

Study finds four circulating miRNAs which could effectively inhibit SARS-CoV-2 replication

In a new study, Chen-Yu Zhang's group from Nanjing University presents a rather striking finding that four circulating miRNAs, which are high in healthy people and much lower in older people and diabetic patients, could effectively inhibit SARS-CoV-2 replication by directly targeting the S protein.

12 Aug 2021

Skin cells could provide better understanding of molecular mechanisms of frontotemporal dementia

A new study from the University of Eastern Finland suggests that skin fibroblasts from frontotemporal dementia patients may be useful in investigating underlying disease mechanisms as well as in biomarker and drug research.

12 Aug 2021

Getting a covid vaccine during pregnancy even more urgent as ICU beds fill up

The Centers for Disease Control and Prevention is doubling down on its recommendation that people who are pregnant get the covid-19 vaccine, in light of new data underscoring its safety and effectiveness throughout pregnancy.

12 Aug 2021

Understanding hypoxia-induced gene expression variations in aggressive type of pancreatic cancer

Cancer cells have evolved a myriad of mechanisms that support their uncontrolled growth. In case of solid tissue tumors, the tumor microenvironment, which consists of extracellular components and conditions surrounding the tumor, is crucial in deciding the fate of the cancer cells.

11 Aug 2021

COVID-19 vaccine likely protects people living with HIV, study shows

A Johns Hopkins Medicine research team has shown that people living with the human immunodeficiency virus (HIV) are likely to be protected against SARS-CoV-2, the virus that causes COVID-19, if they are fully vaccinated.

11 Aug 2021

UC San Diego’s wastewater surveillance system enables early detection of most COVID-19 cases

People infected with SARS-CoV-2, the virus that causes COVID-19, are known to shed it in their stool, even if they aren't experiencing any symptoms.

11 Aug 2021

Mount Sinai study discovers an important clue to multisystem inflammatory syndrome in children

Mount Sinai researchers have found an important clue to a rare but serious aftereffect of COVID-19 in children, known as a multisystem inflammatory syndrome in children or MIS-C.

11 Aug 2021

Scientists develop new approach to identify proteins in the living brain

For the first time, researchers have developed a successful approach for identifying proteins inside different types of neurons in the brain of a living animal.

11 Aug 2021

Fine aerosols generated during talking, singing may play a major role in SARS-CoV-2 transmission

The coronavirus disease 2019 (COVID-19) has been thought to spread primarily when an infected person coughs or sneezes, but little is known about its transmissibility through activities such as breathing, talking, and singing.

11 Aug 2021

A new promising target for broad-spectrum therapeutics against coronaviruses

A recent study by Canadian and US researchers demonstrates how frameshift signals of coronaviruses represent a viable target for developing novel therapeutics with broad-spectrum activity – not only against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but also other constituents of the coronavirus family. The study is currently available on the bioRxiv* preprint server while it undergoes peer review.

11 Aug 2021

Study shows efficacy of gamma irradiation of SARS-CoV-2 vaccine candidate in mouse model

A new study reports a more rapid method of viral inactivation in an effort to increase the appeal of inactivated viral vaccines against the COVID-19 pandemic.

10 Aug 2021

RNA News and Research

Further Reading

Researchers develop new method to quantify protein droplets involved in neurodegenerative diseases

Novel CRISPR-based technique could inspire a new class of medical diagnostics

Researchers develop a new way to tag tumor cells to understand cancer treatment resistance

Study uncovers a subset of human short introns spliced out by a distinct mechanism

Discovery of highly potent neutralizing monoclonal antibodies against SARS-CoV-2

How replication and recombination contribute to emergence of SARS-CoV-2 variants

Study highlights the significance of screening for pre-cancerous Barrett’s esophagus

Optical nanoscopy reveals how SARS-CoV-2 infection alters human airway cells

Innovative therapeutic platform for blood-to-brain delivery of antisense oligonucleotide therapy

Study finds four circulating miRNAs which could effectively inhibit SARS-CoV-2 replication

Skin cells could provide better understanding of molecular mechanisms of frontotemporal dementia

Getting a covid vaccine during pregnancy even more urgent as ICU beds fill up

Understanding hypoxia-induced gene expression variations in aggressive type of pancreatic cancer

COVID-19 vaccine likely protects people living with HIV, study shows

UC San Diego’s wastewater surveillance system enables early detection of most COVID-19 cases

Mount Sinai study discovers an important clue to multisystem inflammatory syndrome in children

Scientists develop new approach to identify proteins in the living brain

Fine aerosols generated during talking, singing may play a major role in SARS-CoV-2 transmission

A new promising target for broad-spectrum therapeutics against coronaviruses

Study shows efficacy of gamma irradiation of SARS-CoV-2 vaccine candidate in mouse model

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