Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

4SC granted U.S. patent for drug to treat rheumatoid arthritis

Martinsried-based drug discovery and development company 4SC AG announced today that the US Patent and Trademark Office (ASPTO) has granted the patent with the US patent number 7,176,241 for its drug candidate SC12267.

6 Feb 2007

Apolipoprotein E gene raises newborns' cerebral palsy risk

Apolipoprotein E (APOE), a gene associated with heightened risk for Alzheimer's disease in adults, can also increase the likelihood that brain-injured newborns will develop cerebral palsy, researchers at Children's Memorial Research Center have discovered.

5 Feb 2007

FoxOs shown to be potential new targets for cancer drugs

In an elegant, multiple-gene knockout experiment, a team of Boston scientists has discovered that a trio of molecules, called FoxOs, are fundamentally critical in preventing some cancers, maintaining blood vessel stability, and in keeping blood-forming stem cells healthy.

29 Jan 2007

Emory University announces new health institute

Emory University announced today a new Global Health Institute that will help address the most pressing health challenges around the world, particularly in poorer nations.

10 Jan 2007

BIO urges Congress to pass Stem Cell Research Enhancement Act

Jim Greenwood, president and CEO of the Biotechnology Industry Organization (BIO), has issued the following statement on H.R. 3, the Stem Cell Research Enhancement Act of 2007.

9 Jan 2007

Amphora sells oncology target to Genentech

Amphora Discovery Corporation, a small molecule drug discovery company, announced today that it has entered into an agreement with Genentech, Inc. pursuant to which Genentech will purchase Amphora's entire program for an unnamed oncology target with the potential to treat multiple oncology indications.

9 Jan 2007

Cytogen issued new patent covering oral drug delivery agents

Cytogen Corporation has announced that it has been issued United States patent number 7,135,457 covering its oral drug delivery agents - random peptide compositions that bind to gastro-intestinal tract (GIT) transport receptors.

28 Nov 2006

Master stem cell capable of producing new heart tissue

Researchers in the United States believe they have discovered a "master" embryonic cardiac stem cell.

22 Nov 2006

New protein structure found - important for drug discovery

Understanding and replicating the diverse ways in which cellular proteins fold and interconnect is key to understanding life processes and major disorders, such as Parkinson's disease.

15 Nov 2006

Bionomics delivers on milestones for cancer, anxiety and multiple sclerosis programs

Australian drug discovery company Bionomics Limited today updated shareholders at its Annual General Meeting on the recent progress of its anti-cancer drug BNC105 and drug discovery programs in anxiety and Multiple Sclerosis.

8 Nov 2006

Lab-on-a-chip nanoscale array monitors cellular processes

Researchers at Tel-Aviv University in Israel have developed a lab-on-a-chip device that can incorporate enzymes and even living cells in a nanoscale array capable of monitoring electrochemical reactions.

30 Oct 2006

New study emphasizes the importance of metabolomics to the advent of personalized medicine

International experts have collaborated on a comprehensive collection of reviews focusing on the emerging interface between metabolomics and pharmacogenomics.

24 Oct 2006

New method of developing antibiotics

University of Minnesota and University of Michigan researchers have discovered a new method of developing antibiotics, an important step in fighting the growing number of drug-resistant infections.

12 Sep 2006

New map for human genome expression

ExonHit Therapeutics has announced the completion of a new messenger RNA (transcripts) map coming from human genome expression.

5 Sep 2006

New drug improves blood flow in diseased arteries

A new drug has been shown to improve blood flow in diseased arteries, reducing the risk of high blood pressure and heart attacks, a Monash University study published today reveals.

4 Sep 2006

Ranbaxy wins two additional Atorvastatin patents in Norway

Ranbaxy Laboratories Limited has announced that a Norwegian court handed down a favorable decision for Ranbaxy in its case against Pfizer, involving two patents on atorvastatin in Norway.

30 Aug 2006

SRU Biosystems OK'd to conduct business

SRU Biosystems announces the United States District Court for the District of Delaware has resolved in SRU's favor a dispute over the content and scope of a permanent injunction order sought by Corning.

2 Aug 2006

US patent granted for 4SC's clinical Project

The Munich-based drug discovery and development company 4SC AG has been informed by the US Patent and Trademark Office (PTO) that the office has granted the patent with the US patent number 7,071,355.

27 Jul 2006

Evotec sells single molecule detection technology to Olympus

Evotec AG has announced that its Tools and Technologies Division has sold the core of its Single Molecule Detection Technology and transferred or licensed the corresponding IP portfolio to Olympus Corporation, Tokyo, Japan.

From Evident Corporation - Life Sciences 24 Jul 2006

Ranbaxy to acquire the Mundogen generic business from GlaxoSmithKline

Ranbaxy, India's largest pharmaceutical company, and among the top ten generic pharmaceutical companies in the world, announced today that the Company has acquired the Mundogen generic business of GlaxoSmithKline.

19 Jul 2006