Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

North American arrival of A(H5N1) influenza raises concerns of potential pandemic outbreak

Rapid global expansion of highly pathogenic avian influenza A(H5N1) viruses in 2021, including reassortment with North American strains, highlights the need for proactive measures to combat their spread and mitigate the risk of a potential pandemic originating from these reassortants.

31 May 2023

Hydrogen inhalation provides a potential protective strategy for astronauts' brain health

Astronauts are affected by various physical and chemical factors during spaceflight, resulting in a series of pathological and physiological changes.

30 May 2023

Modest reduction in beta-amyloidogenic processing of APP may be a viable strategy to prevent Alzheimer's disease

A new study conducted by researchers at the University of Eastern Finland discovered that the APP A673T genetic variant, which protects against Alzheimer’s disease, alters levels of several proteins and peptides linked to amyloid-beta metabolism in human biofluids and cell culture models, including amyloid beta itself.

26 May 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

Higher sunlight and vitamin D exposure is associated with a lower likelihood of having high perceived stress

Researchers from Italy evaluated the association between perceived stress levels and dietary and lifestyle factors.

16 May 2023

Carotenoids' potential in reducing chronic disease risk

Researchers explore the association between the gastrointestinal delivery system and carotenoids.

15 May 2023

A machine-learning approach for the early diagnosis of Parkinson's disease

Scientists discuss a machine learning-based tool that can detect Parkinson's disease years before the first onset of symptoms.

11 May 2023

Healthier diets may lead to greater physical fitness

A healthy diet is associated with greater physical fitness in middle-aged adults, according to research published today in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology.

11 May 2023

Ketogenic diet: A metabolic makeover boosting immunity and battling inflammation

A recent study discusses alterations in the human metabolic fingerprint associated with the keto diet.

8 May 2023

Cannabis product authenticity: a metabolomic big data approach

Researchers examined the aspects of the authentomics of cannabis products.

5 May 2023

The dynamics and interactions between the skin metabolome, microbiome, and UV exposure

Researchers evaluated metabolic profile changes of the skin in relation to microbiota and UV exposure.

5 May 2023

Does carrot-derived rhamnogalacturonan I positively impact gut microbiota composition and function?

Researchers assessed how carrot-derived rhamnogalacturonan I (cRG-I) impacted the human gut microbiota.

28 Apr 2023

Understanding how consumption of beef vs. plant-based burgers alters the lipemic response and gut microbiota

Researchers reviewed the differences in the digestive process between beef and plant-based burgers from ingestion to excretion.

25 Apr 2023

New machine-learning method could help gauge body clock timing to make better health decisions

A new machine-learning method could help us gauge the time of our internal body clock, helping us all make better health decisions, including when and how long to sleep.

24 Apr 2023

Dietary dicarbonyls may improve insulin sensitivity and reduce type 2 diabetes risk

A recent study investigates how dietary intake of dicarbonyls impacts insulin sensitivity and β-cell function and, as a result, the incidence of type 2 diabetes.

18 Apr 2023

Ecological and evolutionary implications of the sharing of metabolites between different microbes in the gut microbiome

The researchers provide important insights into the cross-feeding mechanisms of nutrients in the gut microbiome and their impacts on host health.

18 Apr 2023

Immune checkpoint inhibitor treatment is facilitated by dietary tryptophan metabolite synthesized by Lactobacillus reuteri

Researchers highlight how dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment.

10 Apr 2023

Alzheimer's risk patients may benefit from Mediterranean keto diet, study shows gut microbiome changes

In a recent study published in the Journal of the Alzheimer's Association (AA), researchers examined the effects of a low-carbohydrate-modified Mediterranean ketogenic diet (MMKD) on the gut microbiome and metabolome of patients at risk for Alzheimer's disease (AD).

9 Apr 2023

The impact of perinatal low-calorie sweetener exposure on the development of neural systems involved in metabolic regulation

A study published in the Journal of Clinical Investigation Insight reveals that consumption of low-calorie sweeteners during pregnancy can affect the metabolism and neural development of the offspring.

6 Apr 2023

Interplay between Western diet, gut microbiota, and cancer development

In a review article published in the journal Seminars in Immunology, scientists have explored the relationship between the Western diet, gut microbiota, and cancer development.

4 Apr 2023