Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

RNA profiles of tumor-educated platelets may diagnose cancer, identify potential therapeutic approaches

Analysis of tumor RNA carried in platelets - blood components best known for their role in clotting - may prove to be more useful than other "liquid biopsy" technologies for diagnosing cancer and determining its primary location and potential therapeutic approaches.

31 Oct 2015

Q BioMed signs definitive license agreement with Mannin Research

Q BioMed Inc., a biotechnology acceleration company is pleased to announce it has signed a definitive license, with the option to acquire, the platform technology assets of Mannin Research Inc.

30 Oct 2015

New online tool may allow researchers explore formation of hair follicles

A new online database will empower researchers exploring how hair follicles and the surrounding skin develop, according to an article published recently in the journal Developmental Cell. The work is central to understanding the interactions between stem cells and their environment - or "niche cells" - during fetal development, and will specifically facilitate future attempts to make skin grafts with functional hair follicles or to regenerate lost hair in patients.

30 Oct 2015

New research shows that autophagy can operate in cell nucleus to guard against start of cancer

Autophagy, literally self-eating or the degradation of unwanted cellular bits and pieces by the cell itself, has been shown for the first time to also work in the cell nucleus. In addition, in this setting it plays a role in guarding against the start of cancer, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

29 Oct 2015

UAB researcher awarded NIH grant to study pathogenesis of thrombotic microangiopathy

University of Alabama at Birmingham researcher X. Long Zheng, M.D., Ph.D., has received a five-year, $2.5 million National Institutes of Health grant to study the pathogenesis of thrombotic microangiopathy, or TMA. In simple terms, this means looking for factors that cause or aid the onset of extensive microscopic clots in small blood vessels throughout the body. Though tiny, these spots can damage kidneys, heart and brain, and they can cause death.

29 Oct 2015

Latitude, summer daylight exposure make difference in results for children treated with growth hormone

The rate of growth in children varies with the season while higher latitude and greater summer daylight exposure makes a significant difference in results for children treated with growth hormone, according to new research from The University of Manchester.

29 Oct 2015

Testing amniotic fluid could guide doctors to make delivery planning decisions for preterm births

Analyzing gene expression of an expectant mother's amniotic fluid could give doctors an important tool for deciding when it is safe to deliver premature babies.

28 Oct 2015

Virginia Tech researchers study how specific cytokine influences gene expression patterns in T helper cells

Environment can make all the difference in behavior - even at the cellular level. Scientists at the Virginia Tech Carilion Research Institute have discovered even a small shift in environmental factors can change how a cell in the immune system matures.

28 Oct 2015

Targeting invasive cells could be a new strategy to treat metastatic cancer, say Stony Brook researchers

Most cancer drugs are designed to target dividing cells, but a new study by Stony Brook University researchers suggests that targeting invasive cells may be a new strategy to treat metastatic cancer.

27 Oct 2015

Researchers develop new method to predict people's biological age

New research has shed light on the molecular changes that occur in our bodies as we age. In the largest study of its kind, an international group of researchers, including experts from the University of Exeter's Medical School, examined expression of genes in blood samples from 15,000 people across the world.

26 Oct 2015

Potential new drug target for acute myeloid leukemia

New treatment options are badly needed for acute myeloid leukemia, a relatively rare form of cancer. The malignancy begins in the bone marrow, and from there can spread rapidly to the bloodstream, depriving the body of the essential blood cells that carry oxygen and fight infections.

23 Oct 2015

New test may help predict spread of breast cancer to the brain

Women with particularly aggressive forms of breast cancer could be identified by a test that predicts whether the disease is likely to spread to the brain.

22 Oct 2015

Viking successfully completes safety, tolerability and pharmacokinetic study of VK5211 in elderly subjects

Viking Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on the development of novel, first-in-class or best-in-class therapies for metabolic and endocrine disorders, today announced the successful completion of a short-term safety, tolerability, and pharmacokinetic study of VK5211 in healthy elderly subjects. VK5211, the company's lead program for muscle and bone disorders, is an orally available, non-steroidal selective androgen receptor modulator (SARM) being developed for the treatment of patients recovering from non-elective hip fracture surgery.

20 Oct 2015

Discovery may lead to new anti-metastasis therapies for advanced-stage brain cancer patients

It's no surprise that people enjoy warm places like Hawaii but may suffer in hostile locales such as Antarctica. A tumor suppressor gene called PTEN is similar in that it is affected by the microenvironments of certain bodily organs to which it travels.

20 Oct 2015

New genetic discovery could lead to better treatment for X-linked diseases

Think back to middle school biology class, when you learned that boys have an X and a Y chromosome inside each cell, and girls have two X's.

20 Oct 2015

BET protein family plays key role in regulation of normal neuronal development and function

Regulation of a family of brain proteins known as bromodomain and extra-terminal domain containing transcription regulators (BETs) plays a key role in normal cognition and behavior, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published advanced online on September 21 and in print October 19 in The Journal of Experimental Medicine.

19 Oct 2015

NEB releases new NEBNext Ultra II DNA Library Prep Kit

New England Biolabs today announced the release of the NEBNext Ultra II DNA Library Prep Kit for Illumina next generation sequencing systems. The new Ultra II kit substantially improves upon its predecessor to produce libraries of both higher quality and higher yield from a variety of sample types, including challenging ones, such as formalin-fixed, paraffin-embedded (FFPE) samples and those containing low amounts of input DNA.

From New England Biolabs 16 Oct 2015

Gene Expression News and Research

Further Reading

RNA profiles of tumor-educated platelets may diagnose cancer, identify potential therapeutic approaches

Q BioMed signs definitive license agreement with Mannin Research

New online tool may allow researchers explore formation of hair follicles

New research shows that autophagy can operate in cell nucleus to guard against start of cancer

UAB researcher awarded NIH grant to study pathogenesis of thrombotic microangiopathy

Latitude, summer daylight exposure make difference in results for children treated with growth hormone

Testing amniotic fluid could guide doctors to make delivery planning decisions for preterm births

Virginia Tech researchers study how specific cytokine influences gene expression patterns in T helper cells

Targeting invasive cells could be a new strategy to treat metastatic cancer, say Stony Brook researchers

Researchers develop new method to predict people's biological age

Potential new drug target for acute myeloid leukemia

New test may help predict spread of breast cancer to the brain

Viking successfully completes safety, tolerability and pharmacokinetic study of VK5211 in elderly subjects

Discovery may lead to new anti-metastasis therapies for advanced-stage brain cancer patients

New genetic discovery could lead to better treatment for X-linked diseases

BET protein family plays key role in regulation of normal neuronal development and function

NEB releases new NEBNext Ultra II DNA Library Prep Kit

Study identifies proteins that could help in treating deafness

Scientists use new technology to create gene expression map of inner ear cell development

Thyroid hormone treatment improves cardiac health in female rats with high blood pressure

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