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Gene offers some level of protection from severe Covid

The first evidence of a genetic link explaining why some people who catch Covid-19 don't become sick has been discovered.

5 Jun 2021

A lack of oversight for unproven stem cell interventions is a global public health problem

Authors are urging the WHO to establish an Exert Advisory Committee on Regenerative Medicine to provide harmony to the national regulations on the SCI industry.

4 Jun 2021

Study identifies new genetic variants that cause developmental disorders in children

Non-coding regions of DNA could hold the key to diagnosing developmental disorders in children, new research suggests.

4 Jun 2021

World Health Organization simplifies names of SARS-CoV-2 variants

Now, the World Health Organization (WHO) has assigned simple and easy-to-say labels for key variants of SARS-CoV-2 using letters of the Greek alphabet. The health agency selected these labels after a thorough review of many potential naming systems.

4 Jun 2021

NIH study identifies promising oral antiviral treatment for COVID-19

The experimental drug TEMPOL may be a promising oral antiviral treatment for COVID-19, suggests a study of cell cultures by researchers at the National Institutes of Health.

3 Jun 2021

How bacterial cells have been engineered to produce virus-resistant synthetic polymers

A recent Science paper discusses the utilization of a previously reported synthetic Escherichia coli to produce virus-resistant synthetic polymers.

3 Jun 2021

Study shows how the physical nature of genome changes before and after cell differentiation

The organization of the human genome relies on physics of different states of matter - such as liquid and solid - a team of scientists has discovered. The findings, which reveal how the physical nature of the genome changes as cells transform to serve specific functions, point to new ways to potentially better understand disease and to create improved therapies for cancer and genetic disorders.

3 Jun 2021

Single mutation to bat virus spike protein allows cell entry using human ACE2

In a paper recently uploaded to the preprint server bioRxiv by Kirchhoff et al. (May 31st, 2021) it is demonstrated that a single mutation to the RaTG13 spike protein results in significantly greater affinity towards the human receptor, indicating that the presence of a positively charged amino group at this position better facilitates interaction with the human ACE2 receptor, and helping to identify other viruses with zoonotic potential.

3 Jun 2021

Epigenetic regulation affects the 3D structure of genome

All the cells of an organism share the same DNA sequence, but their functions, shapes or even lifespans vary greatly. This happens because each cell "reads" different chapters of the genome, thus producing alternative sets of proteins and embarking on different paths.

3 Jun 2021

Scientists develop new gene drive with a built-in genetic barrier

CRISPR-based technologies offer enormous potential to benefit human health and safety, from disease eradication to fortified food supplies. As one example, CRISPR-based gene drives, which are engineered to spread specific traits through targeted populations, are being developed to stop the transmission of devastating diseases such as malaria and dengue fever.

3 Jun 2021

Nanopore sequencing contradicts human genome integration of SARS-CoV-2

Now a new preprint research paper posted to the bioRxiv* server dismisses the possibility, raised by that study, that the virus inserts its genetic material into the host cell’s genome.

2 Jun 2021

Newly identified protein could become a target for future cancer treatments

Researchers at the Francis Crick Institute have identified a protein that helps tumours evade the immune system and, in certain types of cancers, is linked to a poorer chance of survival. The protein could become a target for future cancer treatments.

2 Jun 2021

Sinai Health researchers provide an ultra-detailed look at the organization of human cells

Researchers from Sinai Health have published a study providing an ultra-detailed look at the organization of a living human cell, providing a new tool that can help scientists around the world better understand what happens during disease.

2 Jun 2021

Could higher carnitine levels in the blood protect against severe COVID-19?

Researchers at the MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK, found that carnitine and its derivative acetyl-carnitine provide a protective effect against severe COVID-19. Doubling of carnitine or acetyl-carnitine is tied to a 40-percent reduction risk of disease progression.

2 Jun 2021

Could certain genes be associated with a loss of smell in some COVID-19 patients?

Researchers at the 23andMe COVID-19 Team, who help search for genetic links associated with the severity of COVID-19, found that the genes UGT2A1 and UGT2A2 may be associated with the loss of smell in those infected with SARS-CoV-2.

2 Jun 2021

New vaccine candidate with RBD and N protein targets protects against SARS-CoV-2 in preclinical trials

A recent study published in the journal Science Advances, explores the immunization of RBD with the P2 epitope of tetanus toxoid, to enhance its immunogenicity, and also tests the benefit of N protein in the vaccine.

2 Jun 2021

Coronavirus strain associated with dogs found in humans

Coronavirus strain associated with dogs found in swabs taken from pneumonia patients in Malaysia.

2 Jun 2021

Researchers identify new approach to clear toxic Huntingtin protein

Researchers world-wide are focused on clearing the toxic mutant Huntingtin protein that leads to neuronal cell death and systemic dysfunction in Huntington's disease (HD), a devastating, incurable, progressive neurodegenerative genetic disorder.

2 Jun 2021

Molecular subtype of cancer preferentially affects people with Indigenous ancestry

Oncotarget published "Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry" which reported that contrasting with this pattern, the age structure of HCC in Andean people displays a bimodal distribution with half of the patients developing HCC in adolescence and early adulthood.

2 Jun 2021

Study provides new knowledge about molecular mechanisms underlying human traits, diseases

A new study analyzing the association between an individual's genetics (genotype) and their observable characteristics resulting from the interaction of genetics and the environment (phenotype), contributes new knowledge to the understanding of human complex traits and diseases.

1 Jun 2021

Genome News and Research

Gene offers some level of protection from severe Covid

A lack of oversight for unproven stem cell interventions is a global public health problem

Study identifies new genetic variants that cause developmental disorders in children

World Health Organization simplifies names of SARS-CoV-2 variants

NIH study identifies promising oral antiviral treatment for COVID-19

How bacterial cells have been engineered to produce virus-resistant synthetic polymers

Study shows how the physical nature of genome changes before and after cell differentiation

Single mutation to bat virus spike protein allows cell entry using human ACE2

Epigenetic regulation affects the 3D structure of genome

Scientists develop new gene drive with a built-in genetic barrier

Nanopore sequencing contradicts human genome integration of SARS-CoV-2

Newly identified protein could become a target for future cancer treatments

Sinai Health researchers provide an ultra-detailed look at the organization of human cells

Could higher carnitine levels in the blood protect against severe COVID-19?

Could certain genes be associated with a loss of smell in some COVID-19 patients?

New vaccine candidate with RBD and N protein targets protects against SARS-CoV-2 in preclinical trials

Coronavirus strain associated with dogs found in humans

Researchers identify new approach to clear toxic Huntingtin protein

Molecular subtype of cancer preferentially affects people with Indigenous ancestry

Study provides new knowledge about molecular mechanisms underlying human traits, diseases

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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